| Full name: mitochondrial fission regulator 2 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 6q23.3 | ||
| Entrez ID: 113115 | HGNC ID: HGNC:21115 | Ensembl Gene: ENSG00000146410 | OMIM ID: |
Expression of MTFR2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MTFR2 | 113115 | 228069_at | 1.7791 | 0.0386 | |
| GSE26886 | MTFR2 | 113115 | 228069_at | 1.5801 | 0.0010 | |
| GSE45670 | MTFR2 | 113115 | 228069_at | 1.8062 | 0.0000 | |
| GSE53622 | MTFR2 | 113115 | 52455 | 1.0863 | 0.0000 | |
| GSE53624 | MTFR2 | 113115 | 52455 | 1.7704 | 0.0000 | |
| GSE63941 | MTFR2 | 113115 | 228069_at | 2.9514 | 0.0002 | |
| GSE77861 | MTFR2 | 113115 | 228069_at | 1.4886 | 0.0030 | |
| SRP007169 | MTFR2 | 113115 | RNAseq | 2.8337 | 0.0003 | |
| SRP133303 | MTFR2 | 113115 | RNAseq | 1.5844 | 0.0000 | |
| SRP159526 | MTFR2 | 113115 | RNAseq | 0.8933 | 0.0003 | |
| SRP193095 | MTFR2 | 113115 | RNAseq | 1.1438 | 0.0000 | |
| SRP219564 | MTFR2 | 113115 | RNAseq | 1.2711 | 0.0806 |
Upregulated datasets: 10; Downregulated datasets: 0.
Survival by MTFR2 expression:
Note: Click image to view full size file.
Copy number change of MTFR2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MTFR2 | 113115 | 2 | 5 | 23 | |
| GSE20123 | MTFR2 | 113115 | 2 | 3 | 25 | |
| GSE43470 | MTFR2 | 113115 | 5 | 0 | 38 | |
| GSE46452 | MTFR2 | 113115 | 3 | 10 | 46 | |
| GSE47630 | MTFR2 | 113115 | 9 | 4 | 27 | |
| GSE54993 | MTFR2 | 113115 | 3 | 2 | 65 | |
| GSE54994 | MTFR2 | 113115 | 9 | 7 | 37 | |
| GSE60625 | MTFR2 | 113115 | 0 | 1 | 10 | |
| GSE74703 | MTFR2 | 113115 | 4 | 0 | 32 | |
| GSE74704 | MTFR2 | 113115 | 0 | 2 | 18 | |
| TCGA | MTFR2 | 113115 | 12 | 17 | 67 |
Total number of gains: 49; Total number of losses: 51; Total Number of normals: 388.
Somatic mutations of MTFR2:
Generating mutation plots.
Highly correlated genes for MTFR2:
Showing top 20/1460 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MTFR2 | RACGAP1 | 0.878298 | 5 | 0 | 5 |
| MTFR2 | BUB1B | 0.872105 | 5 | 0 | 5 |
| MTFR2 | NCAPH | 0.855967 | 5 | 0 | 5 |
| MTFR2 | TTK | 0.853088 | 7 | 0 | 7 |
| MTFR2 | CDCA2 | 0.845723 | 5 | 0 | 5 |
| MTFR2 | FEN1 | 0.838197 | 5 | 0 | 5 |
| MTFR2 | CENPN | 0.835572 | 7 | 0 | 7 |
| MTFR2 | DTL | 0.833559 | 7 | 0 | 7 |
| MTFR2 | KIF14 | 0.832651 | 7 | 0 | 7 |
| MTFR2 | CCNB2 | 0.831077 | 6 | 0 | 6 |
| MTFR2 | NUF2 | 0.82836 | 7 | 0 | 7 |
| MTFR2 | UHRF1 | 0.827725 | 7 | 0 | 7 |
| MTFR2 | TRIP13 | 0.827383 | 7 | 0 | 7 |
| MTFR2 | RAD51AP1 | 0.827161 | 7 | 0 | 7 |
| MTFR2 | CENPF | 0.825393 | 7 | 0 | 7 |
| MTFR2 | CDCA3 | 0.824861 | 7 | 0 | 7 |
| MTFR2 | KPNA2 | 0.824472 | 5 | 0 | 5 |
| MTFR2 | CDCA5 | 0.822055 | 7 | 0 | 7 |
| MTFR2 | NEK2 | 0.820296 | 7 | 0 | 7 |
| MTFR2 | CDC6 | 0.818842 | 5 | 0 | 5 |
For details and further investigation, click here

