| Full name: transmembrane protein adipocyte associated 1 | Alias Symbol: TPRA40|FLJ32197|TMEM227 | ||
| Type: protein-coding gene | Cytoband: 3q21.3 | ||
| Entrez ID: 131601 | HGNC ID: HGNC:30413 | Ensembl Gene: ENSG00000163870 | OMIM ID: 608336 |
| Drug and gene relationship at DGIdb | |||
Expression of TPRA1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TPRA1 | 131601 | 218855_at | 0.7752 | 0.0711 | |
| GSE20347 | TPRA1 | 131601 | 218855_at | 0.3104 | 0.0272 | |
| GSE23400 | TPRA1 | 131601 | 218855_at | 0.1823 | 0.0029 | |
| GSE26886 | TPRA1 | 131601 | 218855_at | 0.0126 | 0.9613 | |
| GSE29001 | TPRA1 | 131601 | 218855_at | 0.0575 | 0.7968 | |
| GSE38129 | TPRA1 | 131601 | 218855_at | 0.3677 | 0.0003 | |
| GSE45670 | TPRA1 | 131601 | 218855_at | 0.2033 | 0.2067 | |
| GSE53622 | TPRA1 | 131601 | 51357 | 0.1773 | 0.2493 | |
| GSE53624 | TPRA1 | 131601 | 83536 | 0.3165 | 0.0000 | |
| GSE63941 | TPRA1 | 131601 | 218855_at | 0.9761 | 0.0165 | |
| GSE77861 | TPRA1 | 131601 | 218855_at | 0.2061 | 0.2707 | |
| GSE97050 | TPRA1 | 131601 | A_33_P3399373 | -0.0040 | 0.9876 | |
| SRP007169 | TPRA1 | 131601 | RNAseq | -1.0336 | 0.0399 | |
| SRP008496 | TPRA1 | 131601 | RNAseq | -0.8276 | 0.0050 | |
| SRP064894 | TPRA1 | 131601 | RNAseq | 0.3190 | 0.2512 | |
| SRP133303 | TPRA1 | 131601 | RNAseq | 0.1649 | 0.3259 | |
| SRP159526 | TPRA1 | 131601 | RNAseq | 0.5184 | 0.0012 | |
| SRP193095 | TPRA1 | 131601 | RNAseq | 0.1378 | 0.2230 | |
| SRP219564 | TPRA1 | 131601 | RNAseq | 0.6822 | 0.1788 | |
| TCGA | TPRA1 | 131601 | RNAseq | 0.0968 | 0.0772 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by TPRA1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TPRA1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TPRA1 | 131601 | 17 | 0 | 13 | |
| GSE20123 | TPRA1 | 131601 | 17 | 0 | 13 | |
| GSE43470 | TPRA1 | 131601 | 19 | 0 | 24 | |
| GSE46452 | TPRA1 | 131601 | 14 | 5 | 40 | |
| GSE47630 | TPRA1 | 131601 | 17 | 4 | 19 | |
| GSE54993 | TPRA1 | 131601 | 2 | 7 | 61 | |
| GSE54994 | TPRA1 | 131601 | 31 | 3 | 19 | |
| GSE60625 | TPRA1 | 131601 | 0 | 6 | 5 | |
| GSE74703 | TPRA1 | 131601 | 17 | 0 | 19 | |
| GSE74704 | TPRA1 | 131601 | 13 | 0 | 7 | |
| TCGA | TPRA1 | 131601 | 56 | 6 | 34 |
Total number of gains: 203; Total number of losses: 31; Total Number of normals: 254.
Somatic mutations of TPRA1:
Generating mutation plots.
Highly correlated genes for TPRA1:
Showing top 20/714 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TPRA1 | ERGIC2 | 0.806862 | 3 | 0 | 3 |
| TPRA1 | TBC1D25 | 0.799559 | 3 | 0 | 3 |
| TPRA1 | FOXP4 | 0.793617 | 3 | 0 | 3 |
| TPRA1 | RAD18 | 0.776801 | 3 | 0 | 3 |
| TPRA1 | TXLNG | 0.765308 | 3 | 0 | 3 |
| TPRA1 | LRRC58 | 0.742944 | 4 | 0 | 4 |
| TPRA1 | NOM1 | 0.736154 | 3 | 0 | 3 |
| TPRA1 | ALG1 | 0.735613 | 3 | 0 | 3 |
| TPRA1 | KIAA1257 | 0.734134 | 3 | 0 | 3 |
| TPRA1 | NUDT11 | 0.733564 | 3 | 0 | 3 |
| TPRA1 | NCOA6 | 0.729657 | 3 | 0 | 3 |
| TPRA1 | WDR89 | 0.729288 | 3 | 0 | 3 |
| TPRA1 | B3GNT4 | 0.727235 | 3 | 0 | 3 |
| TPRA1 | PRR3 | 0.721768 | 4 | 0 | 3 |
| TPRA1 | QPCTL | 0.719097 | 3 | 0 | 3 |
| TPRA1 | MIS18A | 0.71467 | 4 | 0 | 4 |
| TPRA1 | DUS3L | 0.712314 | 4 | 0 | 4 |
| TPRA1 | USF2 | 0.707913 | 3 | 0 | 3 |
| TPRA1 | LRRC23 | 0.706953 | 3 | 0 | 3 |
| TPRA1 | SLC25A19 | 0.705923 | 4 | 0 | 4 |
For details and further investigation, click here
