| Full name: WD repeat domain 89 | Alias Symbol: MGC9907 | ||
| Type: protein-coding gene | Cytoband: 14q23.2 | ||
| Entrez ID: 112840 | HGNC ID: HGNC:20489 | Ensembl Gene: ENSG00000140006 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of WDR89:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | WDR89 | 112840 | 238650_x_at | 0.1909 | 0.2840 | |
| GSE26886 | WDR89 | 112840 | 238650_x_at | -0.1186 | 0.4670 | |
| GSE45670 | WDR89 | 112840 | 238650_x_at | 0.1146 | 0.0430 | |
| GSE53622 | WDR89 | 112840 | 16562 | 0.5657 | 0.0000 | |
| GSE53624 | WDR89 | 112840 | 16562 | 0.4627 | 0.0000 | |
| GSE63941 | WDR89 | 112840 | 238650_x_at | 0.6306 | 0.0180 | |
| GSE77861 | WDR89 | 112840 | 238650_x_at | 0.0059 | 0.9653 | |
| GSE97050 | WDR89 | 112840 | A_24_P301186 | 0.3705 | 0.1657 | |
| SRP007169 | WDR89 | 112840 | RNAseq | 0.2969 | 0.4698 | |
| SRP008496 | WDR89 | 112840 | RNAseq | 0.4715 | 0.1119 | |
| SRP064894 | WDR89 | 112840 | RNAseq | 0.5098 | 0.0002 | |
| SRP133303 | WDR89 | 112840 | RNAseq | 0.3775 | 0.0179 | |
| SRP159526 | WDR89 | 112840 | RNAseq | 0.3810 | 0.1149 | |
| SRP193095 | WDR89 | 112840 | RNAseq | 0.0009 | 0.9921 | |
| SRP219564 | WDR89 | 112840 | RNAseq | 0.7966 | 0.0619 | |
| TCGA | WDR89 | 112840 | RNAseq | 0.1240 | 0.0449 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by WDR89 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of WDR89:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | WDR89 | 112840 | 7 | 3 | 20 | |
| GSE20123 | WDR89 | 112840 | 7 | 3 | 20 | |
| GSE43470 | WDR89 | 112840 | 8 | 2 | 33 | |
| GSE46452 | WDR89 | 112840 | 16 | 3 | 40 | |
| GSE47630 | WDR89 | 112840 | 11 | 9 | 20 | |
| GSE54993 | WDR89 | 112840 | 3 | 9 | 58 | |
| GSE54994 | WDR89 | 112840 | 18 | 5 | 30 | |
| GSE60625 | WDR89 | 112840 | 0 | 2 | 9 | |
| GSE74703 | WDR89 | 112840 | 7 | 2 | 27 | |
| GSE74704 | WDR89 | 112840 | 3 | 2 | 15 | |
| TCGA | WDR89 | 112840 | 32 | 14 | 50 |
Total number of gains: 112; Total number of losses: 54; Total Number of normals: 322.
Somatic mutations of WDR89:
Generating mutation plots.
Highly correlated genes for WDR89:
Showing top 20/459 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| WDR89 | TRIM28 | 0.771464 | 3 | 0 | 3 |
| WDR89 | UBTD2 | 0.765706 | 3 | 0 | 3 |
| WDR89 | CD3EAP | 0.761202 | 3 | 0 | 3 |
| WDR89 | GPR153 | 0.758331 | 3 | 0 | 3 |
| WDR89 | TSN | 0.752877 | 4 | 0 | 4 |
| WDR89 | TRAP1 | 0.749492 | 3 | 0 | 3 |
| WDR89 | SLC2A9 | 0.741129 | 3 | 0 | 3 |
| WDR89 | BOD1 | 0.739998 | 3 | 0 | 3 |
| WDR89 | BRAT1 | 0.737989 | 3 | 0 | 3 |
| WDR89 | TPRA1 | 0.729288 | 3 | 0 | 3 |
| WDR89 | FANCM | 0.725732 | 4 | 0 | 4 |
| WDR89 | MIS12 | 0.713196 | 4 | 0 | 4 |
| WDR89 | KHK | 0.712171 | 3 | 0 | 3 |
| WDR89 | MMP15 | 0.712134 | 3 | 0 | 3 |
| WDR89 | SMNDC1 | 0.711712 | 3 | 0 | 3 |
| WDR89 | BSG | 0.711275 | 4 | 0 | 3 |
| WDR89 | APOO | 0.710751 | 3 | 0 | 3 |
| WDR89 | G2E3 | 0.706618 | 4 | 0 | 4 |
| WDR89 | DARS2 | 0.705172 | 5 | 0 | 4 |
| WDR89 | SNX6 | 0.703446 | 4 | 0 | 4 |
For details and further investigation, click here
