| Full name: proline rich 3 | Alias Symbol: CAT56|Em:AB014077.1|Em:AB023052.2 | ||
| Type: protein-coding gene | Cytoband: 6p21.33 | ||
| Entrez ID: 80742 | HGNC ID: HGNC:21149 | Ensembl Gene: ENSG00000204576 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of PRR3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PRR3 | 80742 | 204795_at | 0.4362 | 0.1397 | |
| GSE20347 | PRR3 | 80742 | 204795_at | 0.2389 | 0.0469 | |
| GSE23400 | PRR3 | 80742 | 204795_at | 0.1996 | 0.0001 | |
| GSE26886 | PRR3 | 80742 | 204795_at | -0.3534 | 0.0233 | |
| GSE29001 | PRR3 | 80742 | 204795_at | 0.3509 | 0.1526 | |
| GSE38129 | PRR3 | 80742 | 204795_at | 0.2849 | 0.0081 | |
| GSE45670 | PRR3 | 80742 | 204795_at | 0.1829 | 0.2392 | |
| GSE53622 | PRR3 | 80742 | 27886 | 0.4220 | 0.0024 | |
| GSE53624 | PRR3 | 80742 | 27886 | 0.8071 | 0.0000 | |
| GSE63941 | PRR3 | 80742 | 204795_at | 0.8699 | 0.2410 | |
| GSE77861 | PRR3 | 80742 | 204795_at | 0.3074 | 0.0751 | |
| GSE97050 | PRR3 | 80742 | A_33_P3257170 | 0.3153 | 0.2727 | |
| SRP007169 | PRR3 | 80742 | RNAseq | 1.4009 | 0.0222 | |
| SRP064894 | PRR3 | 80742 | RNAseq | 0.7092 | 0.0001 | |
| SRP133303 | PRR3 | 80742 | RNAseq | 0.1678 | 0.4325 | |
| SRP159526 | PRR3 | 80742 | RNAseq | 1.0304 | 0.0160 | |
| SRP193095 | PRR3 | 80742 | RNAseq | 0.5928 | 0.0000 | |
| SRP219564 | PRR3 | 80742 | RNAseq | 0.6362 | 0.0552 | |
| TCGA | PRR3 | 80742 | RNAseq | 0.1966 | 0.0120 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by PRR3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PRR3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PRR3 | 80742 | 5 | 1 | 24 | |
| GSE20123 | PRR3 | 80742 | 5 | 1 | 24 | |
| GSE43470 | PRR3 | 80742 | 5 | 1 | 37 | |
| GSE46452 | PRR3 | 80742 | 1 | 10 | 48 | |
| GSE47630 | PRR3 | 80742 | 7 | 3 | 30 | |
| GSE54993 | PRR3 | 80742 | 2 | 1 | 67 | |
| GSE54994 | PRR3 | 80742 | 11 | 4 | 38 | |
| GSE60625 | PRR3 | 80742 | 0 | 1 | 10 | |
| GSE74703 | PRR3 | 80742 | 5 | 0 | 31 | |
| GSE74704 | PRR3 | 80742 | 2 | 0 | 18 | |
| TCGA | PRR3 | 80742 | 18 | 16 | 62 |
Total number of gains: 61; Total number of losses: 38; Total Number of normals: 389.
Somatic mutations of PRR3:
Generating mutation plots.
Highly correlated genes for PRR3:
Showing top 20/519 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PRR3 | ORAI1 | 0.807817 | 3 | 0 | 3 |
| PRR3 | FAM53B | 0.805214 | 3 | 0 | 3 |
| PRR3 | RAVER1 | 0.802387 | 3 | 0 | 3 |
| PRR3 | TMTC4 | 0.756241 | 4 | 0 | 4 |
| PRR3 | KDM1B | 0.742732 | 4 | 0 | 4 |
| PRR3 | AKT1S1 | 0.738709 | 3 | 0 | 3 |
| PRR3 | SMAD1 | 0.727771 | 3 | 0 | 3 |
| PRR3 | TPRA1 | 0.721768 | 4 | 0 | 3 |
| PRR3 | CSNK1D | 0.719949 | 4 | 0 | 3 |
| PRR3 | CDCA2 | 0.715373 | 3 | 0 | 3 |
| PRR3 | RAB7A | 0.713516 | 3 | 0 | 3 |
| PRR3 | RFX5 | 0.709464 | 4 | 0 | 3 |
| PRR3 | ZNF644 | 0.709457 | 3 | 0 | 3 |
| PRR3 | NAP1L4 | 0.707262 | 3 | 0 | 3 |
| PRR3 | ZNF567 | 0.706887 | 3 | 0 | 3 |
| PRR3 | APEX2 | 0.702902 | 4 | 0 | 4 |
| PRR3 | MCOLN3 | 0.701971 | 3 | 0 | 3 |
| PRR3 | CHMP7 | 0.699288 | 3 | 0 | 3 |
| PRR3 | MED15 | 0.698379 | 3 | 0 | 3 |
| PRR3 | RNF26 | 0.696394 | 3 | 0 | 3 |
For details and further investigation, click here
