| Full name: zinc and ring finger 3 | Alias Symbol: KIAA1133|BK747E2.3|FLJ22057|RNF203 | ||
| Type: protein-coding gene | Cytoband: 22q12.1 | ||
| Entrez ID: 84133 | HGNC ID: HGNC:18126 | Ensembl Gene: ENSG00000183579 | OMIM ID: 612062 |
| Drug and gene relationship at DGIdb | |||
Expression of ZNRF3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZNRF3 | 84133 | 226360_at | -0.2601 | 0.6623 | |
| GSE26886 | ZNRF3 | 84133 | 226360_at | 0.5027 | 0.1695 | |
| GSE45670 | ZNRF3 | 84133 | 226360_at | -0.2608 | 0.2255 | |
| GSE63941 | ZNRF3 | 84133 | 226360_at | 1.0062 | 0.0732 | |
| GSE77861 | ZNRF3 | 84133 | 226360_at | 0.7201 | 0.1584 | |
| GSE97050 | ZNRF3 | 84133 | A_24_P162373 | -0.0871 | 0.7755 | |
| SRP007169 | ZNRF3 | 84133 | RNAseq | 0.6583 | 0.1313 | |
| SRP008496 | ZNRF3 | 84133 | RNAseq | 1.1727 | 0.0223 | |
| SRP064894 | ZNRF3 | 84133 | RNAseq | -0.0567 | 0.8040 | |
| SRP133303 | ZNRF3 | 84133 | RNAseq | 0.0801 | 0.6698 | |
| SRP159526 | ZNRF3 | 84133 | RNAseq | 0.3889 | 0.1484 | |
| SRP193095 | ZNRF3 | 84133 | RNAseq | 0.1407 | 0.3652 | |
| SRP219564 | ZNRF3 | 84133 | RNAseq | 0.3660 | 0.3732 | |
| TCGA | ZNRF3 | 84133 | RNAseq | -0.0626 | 0.4191 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by ZNRF3 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of ZNRF3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZNRF3 | 84133 | 3 | 3 | 24 | |
| GSE20123 | ZNRF3 | 84133 | 3 | 2 | 25 | |
| GSE43470 | ZNRF3 | 84133 | 4 | 6 | 33 | |
| GSE46452 | ZNRF3 | 84133 | 31 | 1 | 27 | |
| GSE47630 | ZNRF3 | 84133 | 8 | 5 | 27 | |
| GSE54993 | ZNRF3 | 84133 | 3 | 6 | 61 | |
| GSE54994 | ZNRF3 | 84133 | 11 | 8 | 34 | |
| GSE60625 | ZNRF3 | 84133 | 5 | 0 | 6 | |
| GSE74703 | ZNRF3 | 84133 | 4 | 5 | 27 | |
| GSE74704 | ZNRF3 | 84133 | 0 | 1 | 19 | |
| TCGA | ZNRF3 | 84133 | 26 | 17 | 53 |
Total number of gains: 98; Total number of losses: 54; Total Number of normals: 336.
Somatic mutations of ZNRF3:
Generating mutation plots.
Highly correlated genes for ZNRF3:
Showing top 20/221 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZNRF3 | NAP1L1 | 0.800673 | 3 | 0 | 3 |
| ZNRF3 | EP400 | 0.799427 | 3 | 0 | 3 |
| ZNRF3 | PGRMC1 | 0.769695 | 3 | 0 | 3 |
| ZNRF3 | MBTPS2 | 0.768679 | 3 | 0 | 3 |
| ZNRF3 | TCEA1 | 0.767873 | 3 | 0 | 3 |
| ZNRF3 | CHD1L | 0.766766 | 3 | 0 | 3 |
| ZNRF3 | UTP23 | 0.757683 | 3 | 0 | 3 |
| ZNRF3 | SNAPIN | 0.755875 | 3 | 0 | 3 |
| ZNRF3 | ZNF623 | 0.75578 | 3 | 0 | 3 |
| ZNRF3 | PDCD2L | 0.752564 | 3 | 0 | 3 |
| ZNRF3 | AP2A2 | 0.751658 | 3 | 0 | 3 |
| ZNRF3 | TMF1 | 0.741912 | 3 | 0 | 3 |
| ZNRF3 | DET1 | 0.740618 | 3 | 0 | 3 |
| ZNRF3 | ZXDB | 0.738221 | 3 | 0 | 3 |
| ZNRF3 | RAD21 | 0.736859 | 3 | 0 | 3 |
| ZNRF3 | TMEM97 | 0.735409 | 3 | 0 | 3 |
| ZNRF3 | RPS27 | 0.729768 | 3 | 0 | 3 |
| ZNRF3 | HNRNPUL2 | 0.727091 | 3 | 0 | 3 |
| ZNRF3 | FZD6 | 0.727071 | 3 | 0 | 3 |
| ZNRF3 | ZNF292 | 0.726128 | 3 | 0 | 3 |
For details and further investigation, click here
