| Full name: collagen triple helix repeat containing 1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 8q22.3 | ||
| Entrez ID: 115908 | HGNC ID: HGNC:18831 | Ensembl Gene: ENSG00000164932 | OMIM ID: 610635 |
| Drug and gene relationship at DGIdb | |||
Expression of CTHRC1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CTHRC1 | 115908 | 225681_at | 3.6961 | 0.0086 | |
| GSE26886 | CTHRC1 | 115908 | 225681_at | 5.5653 | 0.0000 | |
| GSE45670 | CTHRC1 | 115908 | 225681_at | 2.5788 | 0.0017 | |
| GSE53622 | CTHRC1 | 115908 | 142300 | 4.3283 | 0.0000 | |
| GSE53624 | CTHRC1 | 115908 | 142300 | 4.4658 | 0.0000 | |
| GSE63941 | CTHRC1 | 115908 | 225681_at | -5.5572 | 0.0054 | |
| GSE77861 | CTHRC1 | 115908 | 225681_at | 3.3725 | 0.0086 | |
| GSE97050 | CTHRC1 | 115908 | A_23_P111888 | 2.3834 | 0.0684 | |
| SRP007169 | CTHRC1 | 115908 | RNAseq | 7.3354 | 0.0000 | |
| SRP008496 | CTHRC1 | 115908 | RNAseq | 9.5284 | 0.0000 | |
| SRP064894 | CTHRC1 | 115908 | RNAseq | 5.2608 | 0.0000 | |
| SRP133303 | CTHRC1 | 115908 | RNAseq | 4.6532 | 0.0000 | |
| SRP159526 | CTHRC1 | 115908 | RNAseq | 3.7719 | 0.0000 | |
| SRP219564 | CTHRC1 | 115908 | RNAseq | 4.7775 | 0.0000 | |
| TCGA | CTHRC1 | 115908 | RNAseq | 1.5190 | 0.0000 |
Upregulated datasets: 13; Downregulated datasets: 1.
Survival by CTHRC1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CTHRC1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CTHRC1 | 115908 | 16 | 0 | 14 | |
| GSE20123 | CTHRC1 | 115908 | 18 | 0 | 12 | |
| GSE43470 | CTHRC1 | 115908 | 22 | 0 | 21 | |
| GSE46452 | CTHRC1 | 115908 | 24 | 0 | 35 | |
| GSE47630 | CTHRC1 | 115908 | 24 | 0 | 16 | |
| GSE54993 | CTHRC1 | 115908 | 0 | 20 | 50 | |
| GSE54994 | CTHRC1 | 115908 | 37 | 1 | 15 | |
| GSE60625 | CTHRC1 | 115908 | 0 | 4 | 7 | |
| GSE74703 | CTHRC1 | 115908 | 19 | 0 | 17 | |
| GSE74704 | CTHRC1 | 115908 | 11 | 0 | 9 | |
| TCGA | CTHRC1 | 115908 | 60 | 1 | 35 |
Total number of gains: 231; Total number of losses: 26; Total Number of normals: 231.
Somatic mutations of CTHRC1:
Generating mutation plots.
Highly correlated genes for CTHRC1:
Showing top 20/1480 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CTHRC1 | COL5A2 | 0.867283 | 9 | 0 | 9 |
| CTHRC1 | LAMC2 | 0.860583 | 7 | 0 | 7 |
| CTHRC1 | MMP11 | 0.856261 | 6 | 0 | 6 |
| CTHRC1 | COL1A1 | 0.854642 | 9 | 0 | 9 |
| CTHRC1 | MMP1 | 0.85418 | 8 | 0 | 8 |
| CTHRC1 | COL3A1 | 0.841711 | 9 | 0 | 9 |
| CTHRC1 | TTYH3 | 0.827017 | 7 | 0 | 7 |
| CTHRC1 | ADAMTS12 | 0.82665 | 8 | 0 | 8 |
| CTHRC1 | FBN1 | 0.82178 | 4 | 0 | 4 |
| CTHRC1 | LOXL2 | 0.821164 | 8 | 0 | 8 |
| CTHRC1 | MFAP2 | 0.820795 | 9 | 0 | 8 |
| CTHRC1 | PLAU | 0.818856 | 7 | 0 | 7 |
| CTHRC1 | COLGALT1 | 0.810819 | 6 | 0 | 6 |
| CTHRC1 | POSTN | 0.810349 | 9 | 0 | 9 |
| CTHRC1 | VCAN | 0.809769 | 9 | 0 | 9 |
| CTHRC1 | FNDC3B | 0.808347 | 8 | 0 | 8 |
| CTHRC1 | LPCAT1 | 0.808197 | 7 | 0 | 6 |
| CTHRC1 | COL10A1 | 0.806767 | 8 | 0 | 8 |
| CTHRC1 | CDH11 | 0.800899 | 9 | 0 | 9 |
| CTHRC1 | COL6A3 | 0.800099 | 9 | 0 | 9 |
For details and further investigation, click here
