| Full name: nephronectin | Alias Symbol: EGFL6L|POEM | ||
| Type: protein-coding gene | Cytoband: 4q24 | ||
| Entrez ID: 255743 | HGNC ID: HGNC:27405 | Ensembl Gene: ENSG00000168743 | OMIM ID: 610306 |
| Drug and gene relationship at DGIdb | |||
Expression of NPNT:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NPNT | 255743 | 225911_at | 0.9899 | 0.3473 | |
| GSE26886 | NPNT | 255743 | 225911_at | 0.9546 | 0.0110 | |
| GSE45670 | NPNT | 255743 | 225911_at | 0.6595 | 0.0248 | |
| GSE53622 | NPNT | 255743 | 39630 | 0.5441 | 0.0016 | |
| GSE53624 | NPNT | 255743 | 39630 | 0.5972 | 0.0000 | |
| GSE63941 | NPNT | 255743 | 225911_at | 2.9676 | 0.0588 | |
| GSE77861 | NPNT | 255743 | 225911_at | 0.5131 | 0.4558 | |
| GSE97050 | NPNT | 255743 | A_23_P253896 | -0.0086 | 0.9939 | |
| SRP007169 | NPNT | 255743 | RNAseq | 2.6226 | 0.0000 | |
| SRP008496 | NPNT | 255743 | RNAseq | 2.2944 | 0.0000 | |
| SRP064894 | NPNT | 255743 | RNAseq | 0.8587 | 0.0032 | |
| SRP133303 | NPNT | 255743 | RNAseq | 1.7241 | 0.0001 | |
| SRP159526 | NPNT | 255743 | RNAseq | 0.7033 | 0.2048 | |
| SRP193095 | NPNT | 255743 | RNAseq | 0.8703 | 0.0012 | |
| SRP219564 | NPNT | 255743 | RNAseq | 0.5528 | 0.4237 | |
| TCGA | NPNT | 255743 | RNAseq | 0.0152 | 0.9201 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by NPNT expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NPNT:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NPNT | 255743 | 0 | 12 | 18 | |
| GSE20123 | NPNT | 255743 | 0 | 12 | 18 | |
| GSE43470 | NPNT | 255743 | 0 | 13 | 30 | |
| GSE46452 | NPNT | 255743 | 1 | 36 | 22 | |
| GSE47630 | NPNT | 255743 | 0 | 20 | 20 | |
| GSE54993 | NPNT | 255743 | 9 | 0 | 61 | |
| GSE54994 | NPNT | 255743 | 1 | 10 | 42 | |
| GSE60625 | NPNT | 255743 | 0 | 3 | 8 | |
| GSE74703 | NPNT | 255743 | 0 | 11 | 25 | |
| GSE74704 | NPNT | 255743 | 0 | 6 | 14 | |
| TCGA | NPNT | 255743 | 8 | 38 | 50 |
Total number of gains: 19; Total number of losses: 161; Total Number of normals: 308.
Somatic mutations of NPNT:
Generating mutation plots.
Highly correlated genes for NPNT:
Showing top 20/401 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NPNT | PAN2 | 0.773999 | 3 | 0 | 3 |
| NPNT | TRAF5 | 0.765544 | 3 | 0 | 3 |
| NPNT | PTPN14 | 0.756703 | 4 | 0 | 4 |
| NPNT | ZFYVE27 | 0.750907 | 3 | 0 | 3 |
| NPNT | KIAA1257 | 0.75034 | 3 | 0 | 3 |
| NPNT | PHIP | 0.739177 | 4 | 0 | 4 |
| NPNT | IL17RD | 0.738454 | 3 | 0 | 3 |
| NPNT | FKTN | 0.735723 | 3 | 0 | 3 |
| NPNT | RICTOR | 0.731522 | 3 | 0 | 3 |
| NPNT | SLC25A37 | 0.730164 | 3 | 0 | 3 |
| NPNT | POLR2J | 0.727003 | 3 | 0 | 3 |
| NPNT | DNAJC27 | 0.721945 | 3 | 0 | 3 |
| NPNT | ZNF704 | 0.717407 | 4 | 0 | 4 |
| NPNT | KCNE3 | 0.714385 | 3 | 0 | 3 |
| NPNT | TRPC1 | 0.712079 | 3 | 0 | 3 |
| NPNT | FAM168A | 0.708498 | 3 | 0 | 3 |
| NPNT | RFX5 | 0.707661 | 3 | 0 | 3 |
| NPNT | THOC1 | 0.706022 | 3 | 0 | 3 |
| NPNT | BAG2 | 0.701638 | 3 | 0 | 3 |
| NPNT | PELI2 | 0.699544 | 3 | 0 | 3 |
For details and further investigation, click here
