| Full name: trehalase | Alias Symbol: TRE|TREA|MGC129621 | ||
| Type: protein-coding gene | Cytoband: 11q23.3 | ||
| Entrez ID: 11181 | HGNC ID: HGNC:12266 | Ensembl Gene: ENSG00000118094 | OMIM ID: 275360 |
| Drug and gene relationship at DGIdb | |||
Expression of TREH:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TREH | 11181 | 207378_at | -0.3603 | 0.2465 | |
| GSE20347 | TREH | 11181 | 207378_at | -0.4349 | 0.0000 | |
| GSE23400 | TREH | 11181 | 207378_at | -0.2834 | 0.0000 | |
| GSE26886 | TREH | 11181 | 207378_at | -0.3361 | 0.0376 | |
| GSE29001 | TREH | 11181 | 207378_at | -0.4576 | 0.0009 | |
| GSE38129 | TREH | 11181 | 207378_at | -0.4640 | 0.0000 | |
| GSE45670 | TREH | 11181 | 207378_at | -0.3339 | 0.0004 | |
| GSE53622 | TREH | 11181 | 110119 | -1.3881 | 0.0000 | |
| GSE53624 | TREH | 11181 | 110119 | -2.3861 | 0.0000 | |
| GSE63941 | TREH | 11181 | 207378_at | -0.0125 | 0.9467 | |
| GSE77861 | TREH | 11181 | 207378_at | -0.3805 | 0.0482 | |
| GSE97050 | TREH | 11181 | A_23_P104819 | -0.1790 | 0.7180 | |
| SRP064894 | TREH | 11181 | RNAseq | -1.2474 | 0.0511 | |
| SRP133303 | TREH | 11181 | RNAseq | -2.1018 | 0.0000 | |
| SRP159526 | TREH | 11181 | RNAseq | -3.0829 | 0.0000 | |
| SRP193095 | TREH | 11181 | RNAseq | -1.9315 | 0.0000 | |
| SRP219564 | TREH | 11181 | RNAseq | -1.6047 | 0.0237 | |
| TCGA | TREH | 11181 | RNAseq | -4.3434 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 7.
Survival by TREH expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TREH:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TREH | 11181 | 2 | 11 | 17 | |
| GSE20123 | TREH | 11181 | 2 | 11 | 17 | |
| GSE43470 | TREH | 11181 | 2 | 9 | 32 | |
| GSE46452 | TREH | 11181 | 3 | 26 | 30 | |
| GSE47630 | TREH | 11181 | 2 | 19 | 19 | |
| GSE54993 | TREH | 11181 | 10 | 0 | 60 | |
| GSE54994 | TREH | 11181 | 5 | 19 | 29 | |
| GSE60625 | TREH | 11181 | 0 | 3 | 8 | |
| GSE74703 | TREH | 11181 | 1 | 6 | 29 | |
| GSE74704 | TREH | 11181 | 1 | 7 | 12 | |
| TCGA | TREH | 11181 | 4 | 51 | 41 |
Total number of gains: 32; Total number of losses: 162; Total Number of normals: 294.
Somatic mutations of TREH:
Generating mutation plots.
Highly correlated genes for TREH:
Showing top 20/903 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TREH | FAM163B | 0.81908 | 3 | 0 | 3 |
| TREH | MUC22 | 0.785089 | 3 | 0 | 3 |
| TREH | GJD4 | 0.780866 | 3 | 0 | 3 |
| TREH | MFSD2B | 0.774921 | 4 | 0 | 4 |
| TREH | CRTAC1 | 0.774067 | 10 | 0 | 10 |
| TREH | TEN1 | 0.771597 | 3 | 0 | 3 |
| TREH | KRTAP20-1 | 0.768633 | 3 | 0 | 3 |
| TREH | OR2Z1 | 0.760053 | 3 | 0 | 3 |
| TREH | CD164L2 | 0.757848 | 3 | 0 | 3 |
| TREH | PMM1 | 0.755705 | 11 | 0 | 11 |
| TREH | OR10G8 | 0.754289 | 3 | 0 | 3 |
| TREH | CD300LG | 0.750101 | 4 | 0 | 4 |
| TREH | FNDC4 | 0.740882 | 11 | 0 | 11 |
| TREH | BTBD19 | 0.737328 | 4 | 0 | 4 |
| TREH | NCCRP1 | 0.731347 | 3 | 0 | 3 |
| TREH | VAT1 | 0.730596 | 10 | 0 | 10 |
| TREH | ASPG | 0.723465 | 5 | 0 | 5 |
| TREH | EPS8L2 | 0.71903 | 12 | 0 | 12 |
| TREH | ARHGAP40 | 0.718145 | 3 | 0 | 3 |
| TREH | RNF222 | 0.717738 | 3 | 0 | 3 |
For details and further investigation, click here
