| Full name: cartilage acidic protein 1 | Alias Symbol: FLJ10320|CEP-68|ASPIC1 | ||
| Type: protein-coding gene | Cytoband: 10q24.2 | ||
| Entrez ID: 55118 | HGNC ID: HGNC:14882 | Ensembl Gene: ENSG00000095713 | OMIM ID: 606276 |
| Drug and gene relationship at DGIdb | |||
Expression of CRTAC1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CRTAC1 | 55118 | 221204_s_at | -1.0592 | 0.1500 | |
| GSE20347 | CRTAC1 | 55118 | 221204_s_at | -0.6859 | 0.0000 | |
| GSE23400 | CRTAC1 | 55118 | 221204_s_at | -0.4270 | 0.0000 | |
| GSE26886 | CRTAC1 | 55118 | 221204_s_at | -0.9778 | 0.0206 | |
| GSE29001 | CRTAC1 | 55118 | 221204_s_at | -1.1658 | 0.0011 | |
| GSE38129 | CRTAC1 | 55118 | 221204_s_at | -0.7362 | 0.0000 | |
| GSE45670 | CRTAC1 | 55118 | 221204_s_at | -1.3937 | 0.0000 | |
| GSE53622 | CRTAC1 | 55118 | 87674 | -2.5644 | 0.0000 | |
| GSE53624 | CRTAC1 | 55118 | 87674 | -3.1530 | 0.0000 | |
| GSE63941 | CRTAC1 | 55118 | 221204_s_at | 0.3480 | 0.0876 | |
| GSE77861 | CRTAC1 | 55118 | 221204_s_at | -1.1437 | 0.0002 | |
| GSE97050 | CRTAC1 | 55118 | A_23_P431971 | -0.4372 | 0.4587 | |
| SRP007169 | CRTAC1 | 55118 | RNAseq | -6.4941 | 0.0000 | |
| SRP064894 | CRTAC1 | 55118 | RNAseq | -2.8532 | 0.0000 | |
| SRP133303 | CRTAC1 | 55118 | RNAseq | -3.8938 | 0.0000 | |
| SRP159526 | CRTAC1 | 55118 | RNAseq | -2.7723 | 0.0002 | |
| SRP219564 | CRTAC1 | 55118 | RNAseq | -2.7158 | 0.0008 | |
| TCGA | CRTAC1 | 55118 | RNAseq | -0.7619 | 0.1713 |
Upregulated datasets: 0; Downregulated datasets: 10.
Survival by CRTAC1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CRTAC1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CRTAC1 | 55118 | 1 | 8 | 21 | |
| GSE20123 | CRTAC1 | 55118 | 1 | 7 | 22 | |
| GSE43470 | CRTAC1 | 55118 | 0 | 7 | 36 | |
| GSE46452 | CRTAC1 | 55118 | 0 | 11 | 48 | |
| GSE47630 | CRTAC1 | 55118 | 2 | 14 | 24 | |
| GSE54993 | CRTAC1 | 55118 | 8 | 0 | 62 | |
| GSE54994 | CRTAC1 | 55118 | 2 | 11 | 40 | |
| GSE60625 | CRTAC1 | 55118 | 0 | 0 | 11 | |
| GSE74703 | CRTAC1 | 55118 | 0 | 5 | 31 | |
| GSE74704 | CRTAC1 | 55118 | 0 | 4 | 16 | |
| TCGA | CRTAC1 | 55118 | 5 | 28 | 63 |
Total number of gains: 19; Total number of losses: 95; Total Number of normals: 374.
Somatic mutations of CRTAC1:
Generating mutation plots.
Highly correlated genes for CRTAC1:
Showing top 20/742 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CRTAC1 | FAM163B | 0.838826 | 3 | 0 | 3 |
| CRTAC1 | C20orf173 | 0.820811 | 3 | 0 | 3 |
| CRTAC1 | HES5 | 0.805904 | 3 | 0 | 3 |
| CRTAC1 | MUC22 | 0.797324 | 3 | 0 | 3 |
| CRTAC1 | OR10G8 | 0.785621 | 3 | 0 | 3 |
| CRTAC1 | TREH | 0.774067 | 10 | 0 | 10 |
| CRTAC1 | SH3BGRL2 | 0.764207 | 6 | 0 | 6 |
| CRTAC1 | KRTAP20-1 | 0.760304 | 3 | 0 | 3 |
| CRTAC1 | SMDT1 | 0.758507 | 3 | 0 | 3 |
| CRTAC1 | OR2Z1 | 0.751795 | 3 | 0 | 3 |
| CRTAC1 | KRT74 | 0.751687 | 3 | 0 | 3 |
| CRTAC1 | SHROOM3 | 0.751347 | 6 | 0 | 6 |
| CRTAC1 | ZDHHC20 | 0.749596 | 3 | 0 | 3 |
| CRTAC1 | THRSP | 0.748654 | 3 | 0 | 3 |
| CRTAC1 | TEN1 | 0.747831 | 3 | 0 | 3 |
| CRTAC1 | MFSD2B | 0.744655 | 3 | 0 | 3 |
| CRTAC1 | OR1J4 | 0.737435 | 4 | 0 | 4 |
| CRTAC1 | SUMF1 | 0.733016 | 4 | 0 | 4 |
| CRTAC1 | GYS2 | 0.732071 | 10 | 0 | 10 |
| CRTAC1 | ST3GAL4 | 0.727858 | 10 | 0 | 10 |
For details and further investigation, click here
