| Full name: fibronectin type III domain containing 4 | Alias Symbol: FLJ22362|FRCP1 | ||
| Type: protein-coding gene | Cytoband: 2p23.3 | ||
| Entrez ID: 64838 | HGNC ID: HGNC:20239 | Ensembl Gene: ENSG00000115226 | OMIM ID: 611905 |
| Drug and gene relationship at DGIdb | |||
Expression of FNDC4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FNDC4 | 64838 | 218843_at | -0.9396 | 0.1144 | |
| GSE20347 | FNDC4 | 64838 | 218843_at | -1.2647 | 0.0000 | |
| GSE23400 | FNDC4 | 64838 | 218843_at | -0.7095 | 0.0000 | |
| GSE26886 | FNDC4 | 64838 | 218843_at | -1.3824 | 0.0000 | |
| GSE29001 | FNDC4 | 64838 | 218843_at | -1.5031 | 0.0000 | |
| GSE38129 | FNDC4 | 64838 | 218843_at | -1.1934 | 0.0000 | |
| GSE45670 | FNDC4 | 64838 | 218843_at | -0.8880 | 0.0003 | |
| GSE53622 | FNDC4 | 64838 | 61725 | -2.2604 | 0.0000 | |
| GSE53624 | FNDC4 | 64838 | 61725 | -3.1140 | 0.0000 | |
| GSE63941 | FNDC4 | 64838 | 218843_at | -0.4949 | 0.0277 | |
| GSE77861 | FNDC4 | 64838 | 218843_at | -0.9089 | 0.0045 | |
| GSE97050 | FNDC4 | 64838 | A_23_P16834 | -0.9057 | 0.2272 | |
| SRP007169 | FNDC4 | 64838 | RNAseq | -5.4638 | 0.0000 | |
| SRP008496 | FNDC4 | 64838 | RNAseq | -4.5789 | 0.0000 | |
| SRP064894 | FNDC4 | 64838 | RNAseq | -2.1025 | 0.0000 | |
| SRP133303 | FNDC4 | 64838 | RNAseq | -2.5807 | 0.0000 | |
| SRP159526 | FNDC4 | 64838 | RNAseq | -1.5957 | 0.0148 | |
| SRP193095 | FNDC4 | 64838 | RNAseq | -3.1155 | 0.0000 | |
| SRP219564 | FNDC4 | 64838 | RNAseq | -2.3706 | 0.0001 | |
| TCGA | FNDC4 | 64838 | RNAseq | -0.3429 | 0.0512 |
Upregulated datasets: 0; Downregulated datasets: 13.
Survival by FNDC4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FNDC4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FNDC4 | 64838 | 11 | 2 | 17 | |
| GSE20123 | FNDC4 | 64838 | 11 | 2 | 17 | |
| GSE43470 | FNDC4 | 64838 | 3 | 1 | 39 | |
| GSE46452 | FNDC4 | 64838 | 2 | 4 | 53 | |
| GSE47630 | FNDC4 | 64838 | 8 | 0 | 32 | |
| GSE54993 | FNDC4 | 64838 | 0 | 6 | 64 | |
| GSE54994 | FNDC4 | 64838 | 10 | 0 | 43 | |
| GSE60625 | FNDC4 | 64838 | 0 | 3 | 8 | |
| GSE74703 | FNDC4 | 64838 | 3 | 0 | 33 | |
| GSE74704 | FNDC4 | 64838 | 9 | 1 | 10 | |
| TCGA | FNDC4 | 64838 | 36 | 2 | 58 |
Total number of gains: 93; Total number of losses: 21; Total Number of normals: 374.
Somatic mutations of FNDC4:
Generating mutation plots.
Highly correlated genes for FNDC4:
Showing top 20/1360 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FNDC4 | GYS2 | 0.884073 | 10 | 0 | 10 |
| FNDC4 | SFTA2 | 0.861365 | 4 | 0 | 4 |
| FNDC4 | UPK1A | 0.854233 | 11 | 0 | 11 |
| FNDC4 | PAQR8 | 0.853304 | 6 | 0 | 6 |
| FNDC4 | EHD3 | 0.845681 | 11 | 0 | 11 |
| FNDC4 | ST3GAL4 | 0.84287 | 11 | 0 | 11 |
| FNDC4 | KRT78 | 0.840652 | 7 | 0 | 7 |
| FNDC4 | RANBP9 | 0.838812 | 10 | 0 | 10 |
| FNDC4 | CGNL1 | 0.834679 | 6 | 0 | 6 |
| FNDC4 | ATG9B | 0.834343 | 6 | 0 | 6 |
| FNDC4 | C18orf25 | 0.833481 | 10 | 0 | 10 |
| FNDC4 | SPINK7 | 0.831916 | 7 | 0 | 7 |
| FNDC4 | CYSRT1 | 0.831533 | 6 | 0 | 6 |
| FNDC4 | ACER1 | 0.830232 | 7 | 0 | 7 |
| FNDC4 | UBL3 | 0.83022 | 11 | 0 | 11 |
| FNDC4 | GDPD3 | 0.830164 | 11 | 0 | 11 |
| FNDC4 | SLC46A2 | 0.829085 | 6 | 0 | 6 |
| FNDC4 | MAPK3 | 0.828632 | 11 | 0 | 11 |
| FNDC4 | ANKRD35 | 0.827465 | 7 | 0 | 7 |
| FNDC4 | SH3GL1 | 0.827214 | 10 | 0 | 10 |
For details and further investigation, click here
