| Full name: vesicle amine transport 1 | Alias Symbol: VATI|FLJ20230 | ||
| Type: protein-coding gene | Cytoband: 17q21.31 | ||
| Entrez ID: 10493 | HGNC ID: HGNC:16919 | Ensembl Gene: ENSG00000108828 | OMIM ID: 604631 |
| Drug and gene relationship at DGIdb | |||
Expression of VAT1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | VAT1 | 10493 | 208626_s_at | -0.4730 | 0.1796 | |
| GSE20347 | VAT1 | 10493 | 208626_s_at | -1.2391 | 0.0000 | |
| GSE23400 | VAT1 | 10493 | 208626_s_at | -0.8827 | 0.0000 | |
| GSE26886 | VAT1 | 10493 | 208626_s_at | -1.3077 | 0.0000 | |
| GSE29001 | VAT1 | 10493 | 208626_s_at | -1.4648 | 0.0000 | |
| GSE38129 | VAT1 | 10493 | 208626_s_at | -1.0673 | 0.0000 | |
| GSE45670 | VAT1 | 10493 | 208626_s_at | -0.9144 | 0.0002 | |
| GSE53622 | VAT1 | 10493 | 29369 | -1.3125 | 0.0000 | |
| GSE53624 | VAT1 | 10493 | 29369 | -1.2999 | 0.0000 | |
| GSE63941 | VAT1 | 10493 | 208626_s_at | -2.2614 | 0.0005 | |
| GSE77861 | VAT1 | 10493 | 208626_s_at | -1.2074 | 0.0004 | |
| GSE97050 | VAT1 | 10493 | A_24_P152527 | -0.4666 | 0.2156 | |
| SRP007169 | VAT1 | 10493 | RNAseq | -2.8717 | 0.0000 | |
| SRP008496 | VAT1 | 10493 | RNAseq | -2.8575 | 0.0000 | |
| SRP064894 | VAT1 | 10493 | RNAseq | -0.7973 | 0.0020 | |
| SRP133303 | VAT1 | 10493 | RNAseq | -1.3272 | 0.0000 | |
| SRP159526 | VAT1 | 10493 | RNAseq | -1.6625 | 0.0000 | |
| SRP193095 | VAT1 | 10493 | RNAseq | -1.6206 | 0.0000 | |
| SRP219564 | VAT1 | 10493 | RNAseq | -1.3482 | 0.0000 | |
| TCGA | VAT1 | 10493 | RNAseq | -0.0309 | 0.5828 |
Upregulated datasets: 0; Downregulated datasets: 14.
Survival by VAT1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of VAT1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | VAT1 | 10493 | 6 | 2 | 22 | |
| GSE20123 | VAT1 | 10493 | 6 | 2 | 22 | |
| GSE43470 | VAT1 | 10493 | 1 | 2 | 40 | |
| GSE46452 | VAT1 | 10493 | 34 | 0 | 25 | |
| GSE47630 | VAT1 | 10493 | 8 | 1 | 31 | |
| GSE54993 | VAT1 | 10493 | 3 | 4 | 63 | |
| GSE54994 | VAT1 | 10493 | 8 | 5 | 40 | |
| GSE60625 | VAT1 | 10493 | 4 | 0 | 7 | |
| GSE74703 | VAT1 | 10493 | 1 | 1 | 34 | |
| GSE74704 | VAT1 | 10493 | 4 | 1 | 15 | |
| TCGA | VAT1 | 10493 | 22 | 7 | 67 |
Total number of gains: 97; Total number of losses: 25; Total Number of normals: 366.
Somatic mutations of VAT1:
Generating mutation plots.
Highly correlated genes for VAT1:
Showing top 20/1418 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| VAT1 | SFTA2 | 0.870493 | 4 | 0 | 4 |
| VAT1 | GYS2 | 0.864365 | 10 | 0 | 10 |
| VAT1 | CYSRT1 | 0.858113 | 6 | 0 | 6 |
| VAT1 | KRT78 | 0.857828 | 7 | 0 | 7 |
| VAT1 | EHD3 | 0.853117 | 12 | 0 | 12 |
| VAT1 | EPS8L2 | 0.835714 | 10 | 0 | 10 |
| VAT1 | PMM1 | 0.835137 | 11 | 0 | 11 |
| VAT1 | RANBP9 | 0.832755 | 11 | 0 | 11 |
| VAT1 | ANXA9 | 0.831261 | 11 | 0 | 11 |
| VAT1 | CLIC3 | 0.83104 | 9 | 0 | 9 |
| VAT1 | GDPD3 | 0.830559 | 11 | 0 | 11 |
| VAT1 | RAET1E | 0.824337 | 6 | 0 | 6 |
| VAT1 | MGLL | 0.822308 | 12 | 0 | 12 |
| VAT1 | ECM1 | 0.821178 | 12 | 0 | 12 |
| VAT1 | SH3BGRL2 | 0.818352 | 7 | 0 | 7 |
| VAT1 | SASH1 | 0.817117 | 12 | 0 | 12 |
| VAT1 | PSCA | 0.816918 | 8 | 0 | 8 |
| VAT1 | TOM1 | 0.815673 | 11 | 0 | 11 |
| VAT1 | A2ML1 | 0.814372 | 7 | 0 | 7 |
| VAT1 | SLC35C1 | 0.813757 | 10 | 0 | 10 |
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