| Full name: tetraspanin 12 | Alias Symbol: NET-2 | ||
| Type: protein-coding gene | Cytoband: 7q31.31 | ||
| Entrez ID: 23554 | HGNC ID: HGNC:21641 | Ensembl Gene: ENSG00000106025 | OMIM ID: 613138 |
| Drug and gene relationship at DGIdb | |||
Expression of TSPAN12:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TSPAN12 | 23554 | 219274_at | -0.8125 | 0.5119 | |
| GSE20347 | TSPAN12 | 23554 | 219274_at | -0.6307 | 0.0099 | |
| GSE23400 | TSPAN12 | 23554 | 219274_at | -0.1055 | 0.0032 | |
| GSE26886 | TSPAN12 | 23554 | 219274_at | -2.4138 | 0.0003 | |
| GSE29001 | TSPAN12 | 23554 | 219274_at | -0.6420 | 0.1705 | |
| GSE38129 | TSPAN12 | 23554 | 219274_at | -0.9357 | 0.0052 | |
| GSE45670 | TSPAN12 | 23554 | 219274_at | -1.4325 | 0.0062 | |
| GSE53622 | TSPAN12 | 23554 | 69854 | -0.9939 | 0.0000 | |
| GSE53624 | TSPAN12 | 23554 | 69854 | -1.0586 | 0.0000 | |
| GSE63941 | TSPAN12 | 23554 | 219274_at | -4.2512 | 0.0054 | |
| GSE77861 | TSPAN12 | 23554 | 230625_s_at | -0.0654 | 0.7049 | |
| SRP007169 | TSPAN12 | 23554 | RNAseq | -0.6453 | 0.3053 | |
| SRP064894 | TSPAN12 | 23554 | RNAseq | -0.6211 | 0.0658 | |
| SRP133303 | TSPAN12 | 23554 | RNAseq | -0.5901 | 0.2039 | |
| SRP159526 | TSPAN12 | 23554 | RNAseq | -0.5186 | 0.1920 | |
| SRP193095 | TSPAN12 | 23554 | RNAseq | -1.0148 | 0.0035 | |
| SRP219564 | TSPAN12 | 23554 | RNAseq | -0.6733 | 0.2554 | |
| TCGA | TSPAN12 | 23554 | RNAseq | -1.1920 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 6.
Survival by TSPAN12 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TSPAN12:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TSPAN12 | 23554 | 6 | 2 | 22 | |
| GSE20123 | TSPAN12 | 23554 | 8 | 2 | 20 | |
| GSE43470 | TSPAN12 | 23554 | 3 | 3 | 37 | |
| GSE46452 | TSPAN12 | 23554 | 8 | 1 | 50 | |
| GSE47630 | TSPAN12 | 23554 | 7 | 4 | 29 | |
| GSE54993 | TSPAN12 | 23554 | 2 | 6 | 62 | |
| GSE54994 | TSPAN12 | 23554 | 10 | 6 | 37 | |
| GSE60625 | TSPAN12 | 23554 | 0 | 0 | 11 | |
| GSE74703 | TSPAN12 | 23554 | 3 | 3 | 30 | |
| GSE74704 | TSPAN12 | 23554 | 6 | 2 | 12 | |
| TCGA | TSPAN12 | 23554 | 28 | 20 | 48 |
Total number of gains: 81; Total number of losses: 49; Total Number of normals: 358.
Somatic mutations of TSPAN12:
Generating mutation plots.
Highly correlated genes for TSPAN12:
Showing top 20/380 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TSPAN12 | RSPO3 | 0.714517 | 3 | 0 | 3 |
| TSPAN12 | MLYCD | 0.671442 | 3 | 0 | 3 |
| TSPAN12 | FAM13C | 0.6435 | 4 | 0 | 4 |
| TSPAN12 | SARM1 | 0.637997 | 3 | 0 | 3 |
| TSPAN12 | THYN1 | 0.635912 | 5 | 0 | 4 |
| TSPAN12 | LINC01279 | 0.635037 | 3 | 0 | 3 |
| TSPAN12 | KL | 0.63372 | 5 | 0 | 5 |
| TSPAN12 | LIFR | 0.632439 | 5 | 0 | 5 |
| TSPAN12 | SLC4A4 | 0.628884 | 6 | 0 | 6 |
| TSPAN12 | BRAF | 0.621861 | 3 | 0 | 3 |
| TSPAN12 | RNF125 | 0.617254 | 6 | 0 | 5 |
| TSPAN12 | RAI2 | 0.615245 | 8 | 0 | 6 |
| TSPAN12 | C9orf152 | 0.613526 | 5 | 0 | 5 |
| TSPAN12 | ZNF677 | 0.611984 | 6 | 0 | 4 |
| TSPAN12 | NR3C2 | 0.610291 | 9 | 0 | 8 |
| TSPAN12 | TMEM100 | 0.60972 | 8 | 0 | 7 |
| TSPAN12 | SLC2A10 | 0.608868 | 7 | 0 | 5 |
| TSPAN12 | TCF21 | 0.608776 | 7 | 0 | 6 |
| TSPAN12 | EMCN | 0.60651 | 6 | 0 | 5 |
| TSPAN12 | RNF150 | 0.60541 | 6 | 0 | 5 |
For details and further investigation, click here
