| Full name: endomucin | Alias Symbol: MUC14 | ||
| Type: protein-coding gene | Cytoband: 4q24 | ||
| Entrez ID: 51705 | HGNC ID: HGNC:16041 | Ensembl Gene: ENSG00000164035 | OMIM ID: 608350 |
| Drug and gene relationship at DGIdb | |||
Expression of EMCN:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | EMCN | 51705 | 222885_at | -1.0979 | 0.1182 | |
| GSE20347 | EMCN | 51705 | 219436_s_at | -0.2902 | 0.0003 | |
| GSE23400 | EMCN | 51705 | 219436_s_at | -0.2596 | 0.0000 | |
| GSE26886 | EMCN | 51705 | 222885_at | -1.1263 | 0.0000 | |
| GSE29001 | EMCN | 51705 | 219436_s_at | -0.0832 | 0.5235 | |
| GSE38129 | EMCN | 51705 | 219436_s_at | -0.6307 | 0.0075 | |
| GSE45670 | EMCN | 51705 | 222885_at | -1.5712 | 0.0002 | |
| GSE63941 | EMCN | 51705 | 219436_s_at | 0.0088 | 0.9535 | |
| GSE77861 | EMCN | 51705 | 222885_at | -0.0886 | 0.6252 | |
| GSE97050 | EMCN | 51705 | A_23_P382065 | 0.1124 | 0.7015 | |
| SRP007169 | EMCN | 51705 | RNAseq | -0.8317 | 0.0998 | |
| SRP008496 | EMCN | 51705 | RNAseq | -0.3285 | 0.4138 | |
| SRP064894 | EMCN | 51705 | RNAseq | 0.0420 | 0.9066 | |
| SRP133303 | EMCN | 51705 | RNAseq | -1.2376 | 0.0001 | |
| SRP159526 | EMCN | 51705 | RNAseq | -0.5696 | 0.2936 | |
| SRP193095 | EMCN | 51705 | RNAseq | -0.4516 | 0.0148 | |
| SRP219564 | EMCN | 51705 | RNAseq | -0.3026 | 0.6777 | |
| TCGA | EMCN | 51705 | RNAseq | -0.7425 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by EMCN expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of EMCN:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | EMCN | 51705 | 0 | 12 | 18 | |
| GSE20123 | EMCN | 51705 | 0 | 12 | 18 | |
| GSE43470 | EMCN | 51705 | 0 | 13 | 30 | |
| GSE46452 | EMCN | 51705 | 1 | 36 | 22 | |
| GSE47630 | EMCN | 51705 | 0 | 20 | 20 | |
| GSE54993 | EMCN | 51705 | 9 | 0 | 61 | |
| GSE54994 | EMCN | 51705 | 1 | 11 | 41 | |
| GSE60625 | EMCN | 51705 | 0 | 3 | 8 | |
| GSE74703 | EMCN | 51705 | 0 | 11 | 25 | |
| GSE74704 | EMCN | 51705 | 0 | 6 | 14 | |
| TCGA | EMCN | 51705 | 8 | 40 | 48 |
Total number of gains: 19; Total number of losses: 164; Total Number of normals: 305.
Somatic mutations of EMCN:
Generating mutation plots.
Highly correlated genes for EMCN:
Showing top 20/887 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| EMCN | FBXO8 | 0.816348 | 3 | 0 | 3 |
| EMCN | FAM13C | 0.807062 | 4 | 0 | 4 |
| EMCN | AP3M1 | 0.800625 | 3 | 0 | 3 |
| EMCN | CYP4V2 | 0.798863 | 3 | 0 | 3 |
| EMCN | FIBIN | 0.790632 | 3 | 0 | 3 |
| EMCN | ZNF423 | 0.788256 | 5 | 0 | 5 |
| EMCN | FGF7 | 0.782665 | 6 | 0 | 5 |
| EMCN | SYNE1 | 0.779105 | 5 | 0 | 5 |
| EMCN | CNRIP1 | 0.773193 | 4 | 0 | 4 |
| EMCN | NR2F2 | 0.768237 | 5 | 0 | 5 |
| EMCN | SAMD15 | 0.766501 | 3 | 0 | 3 |
| EMCN | FRY | 0.761946 | 5 | 0 | 5 |
| EMCN | PTGIS | 0.760037 | 5 | 0 | 5 |
| EMCN | FZD4 | 0.756301 | 6 | 0 | 6 |
| EMCN | ACVRL1 | 0.753544 | 4 | 0 | 4 |
| EMCN | LINC01140 | 0.751959 | 4 | 0 | 4 |
| EMCN | PEG3 | 0.750245 | 6 | 0 | 6 |
| EMCN | EBF1 | 0.750239 | 4 | 0 | 3 |
| EMCN | PRKAR2B | 0.750219 | 5 | 0 | 5 |
| EMCN | EDNRB | 0.746893 | 5 | 0 | 4 |
For details and further investigation, click here
