| Full name: thrombospondin type laminin G domain and EAR repeats | Alias Symbol: MGC11251|TSP-EAR | ||
| Type: protein-coding gene | Cytoband: 21q22.3 | ||
| Entrez ID: 54084 | HGNC ID: HGNC:1268 | Ensembl Gene: ENSG00000175894 | OMIM ID: 612920 |
| Drug and gene relationship at DGIdb | |||
Expression of TSPEAR:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TSPEAR | 54084 | 1552570_at | -0.0789 | 0.6944 | |
| GSE26886 | TSPEAR | 54084 | 1555049_at | 0.0018 | 0.9880 | |
| GSE45670 | TSPEAR | 54084 | 1555049_at | 0.1160 | 0.1683 | |
| GSE53622 | TSPEAR | 54084 | 71624 | 0.3064 | 0.1895 | |
| GSE53624 | TSPEAR | 54084 | 71624 | -0.1108 | 0.5449 | |
| GSE63941 | TSPEAR | 54084 | 1555049_at | 0.0088 | 0.9544 | |
| GSE77861 | TSPEAR | 54084 | 1555049_at | -0.0570 | 0.7052 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TSPEAR expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of TSPEAR:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TSPEAR | 54084 | 2 | 8 | 20 | |
| GSE20123 | TSPEAR | 54084 | 2 | 8 | 20 | |
| GSE43470 | TSPEAR | 54084 | 0 | 13 | 30 | |
| GSE46452 | TSPEAR | 54084 | 1 | 21 | 37 | |
| GSE47630 | TSPEAR | 54084 | 6 | 17 | 17 | |
| GSE54993 | TSPEAR | 54084 | 8 | 1 | 61 | |
| GSE54994 | TSPEAR | 54084 | 4 | 8 | 41 | |
| GSE60625 | TSPEAR | 54084 | 0 | 0 | 11 | |
| GSE74703 | TSPEAR | 54084 | 0 | 10 | 26 | |
| GSE74704 | TSPEAR | 54084 | 1 | 4 | 15 | |
| TCGA | TSPEAR | 54084 | 9 | 38 | 49 |
Total number of gains: 33; Total number of losses: 128; Total Number of normals: 327.
Somatic mutations of TSPEAR:
Generating mutation plots.
Highly correlated genes for TSPEAR:
Showing all 18 correlated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TSPEAR | LRTM2 | 0.686778 | 3 | 0 | 3 |
| TSPEAR | NMUR1 | 0.637766 | 3 | 0 | 3 |
| TSPEAR | SRPK3 | 0.637033 | 3 | 0 | 3 |
| TSPEAR | TSKS | 0.63328 | 3 | 0 | 3 |
| TSPEAR | SNX8 | 0.631347 | 3 | 0 | 3 |
| TSPEAR | S100A1 | 0.629073 | 3 | 0 | 3 |
| TSPEAR | APC2 | 0.624547 | 3 | 0 | 3 |
| TSPEAR | DPEP3 | 0.612251 | 3 | 0 | 3 |
| TSPEAR | PRM1 | 0.601917 | 3 | 0 | 3 |
| TSPEAR | CLRN3 | 0.595803 | 3 | 0 | 3 |
| TSPEAR | OR1F1 | 0.592081 | 3 | 0 | 3 |
| TSPEAR | ESPNL | 0.589614 | 3 | 0 | 3 |
| TSPEAR | MYL3 | 0.573922 | 4 | 0 | 3 |
| TSPEAR | SPDEF | 0.558293 | 3 | 0 | 3 |
| TSPEAR | EPHA3 | 0.553297 | 3 | 0 | 3 |
| TSPEAR | ISLR2 | 0.53607 | 3 | 0 | 3 |
| TSPEAR | SSPO | 0.533019 | 5 | 0 | 3 |
| TSPEAR | IL25 | 0.526798 | 4 | 0 | 3 |
For details and further investigation, click here
