| Full name: interleukin 25 | Alias Symbol: IL-25|IL-17E | ||
| Type: protein-coding gene | Cytoband: 14q11.2 | ||
| Entrez ID: 64806 | HGNC ID: HGNC:13765 | Ensembl Gene: ENSG00000166090 | OMIM ID: 605658 |
| Drug and gene relationship at DGIdb | |||
Expression of IL25:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | IL25 | 64806 | 220971_at | -0.1114 | 0.5709 | |
| GSE20347 | IL25 | 64806 | 220971_at | 0.0273 | 0.7673 | |
| GSE23400 | IL25 | 64806 | 220971_at | -0.2148 | 0.0000 | |
| GSE26886 | IL25 | 64806 | 220971_at | -0.0941 | 0.4261 | |
| GSE29001 | IL25 | 64806 | 220971_at | -0.1088 | 0.5532 | |
| GSE38129 | IL25 | 64806 | 220971_at | -0.0052 | 0.9637 | |
| GSE45670 | IL25 | 64806 | 220971_at | 0.1872 | 0.0406 | |
| GSE53622 | IL25 | 64806 | 133754 | 0.5996 | 0.0009 | |
| GSE53624 | IL25 | 64806 | 133754 | 0.3747 | 0.0008 | |
| GSE63941 | IL25 | 64806 | 220971_at | 0.0538 | 0.7222 | |
| GSE77861 | IL25 | 64806 | 220971_at | -0.0198 | 0.8778 | |
| TCGA | IL25 | 64806 | RNAseq | 0.5508 | 0.6349 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by IL25 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of IL25:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | IL25 | 64806 | 9 | 1 | 20 | |
| GSE20123 | IL25 | 64806 | 9 | 1 | 20 | |
| GSE43470 | IL25 | 64806 | 7 | 2 | 34 | |
| GSE46452 | IL25 | 64806 | 17 | 2 | 40 | |
| GSE47630 | IL25 | 64806 | 11 | 10 | 19 | |
| GSE54993 | IL25 | 64806 | 3 | 11 | 56 | |
| GSE54994 | IL25 | 64806 | 18 | 5 | 30 | |
| GSE60625 | IL25 | 64806 | 0 | 2 | 9 | |
| GSE74703 | IL25 | 64806 | 6 | 2 | 28 | |
| GSE74704 | IL25 | 64806 | 4 | 1 | 15 | |
| TCGA | IL25 | 64806 | 27 | 14 | 55 |
Total number of gains: 111; Total number of losses: 51; Total Number of normals: 326.
Somatic mutations of IL25:
Generating mutation plots.
Highly correlated genes for IL25:
Showing top 20/897 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| IL25 | SLC10A1 | 0.716704 | 5 | 0 | 5 |
| IL25 | MYOG | 0.716225 | 4 | 0 | 4 |
| IL25 | MYL1 | 0.713979 | 3 | 0 | 3 |
| IL25 | PRSS50 | 0.707579 | 3 | 0 | 3 |
| IL25 | IKZF3 | 0.703325 | 3 | 0 | 3 |
| IL25 | FSCN3 | 0.70304 | 6 | 0 | 6 |
| IL25 | GRIK5 | 0.701833 | 5 | 0 | 5 |
| IL25 | CCDC9 | 0.698923 | 4 | 0 | 4 |
| IL25 | RORC | 0.697067 | 6 | 0 | 6 |
| IL25 | SSTR4 | 0.695293 | 5 | 0 | 4 |
| IL25 | KCNJ3 | 0.694546 | 5 | 0 | 5 |
| IL25 | APBA1 | 0.68656 | 5 | 0 | 4 |
| IL25 | KRTAP5-8 | 0.685956 | 5 | 0 | 5 |
| IL25 | CYP11B2 | 0.682423 | 4 | 0 | 4 |
| IL25 | MSH4 | 0.682123 | 3 | 0 | 3 |
| IL25 | BSN | 0.681606 | 3 | 0 | 3 |
| IL25 | ATRNL1 | 0.678915 | 3 | 0 | 3 |
| IL25 | ARVCF | 0.678306 | 3 | 0 | 3 |
| IL25 | JAK3 | 0.675131 | 5 | 0 | 4 |
| IL25 | GLP1R | 0.670085 | 6 | 0 | 5 |
For details and further investigation, click here
