| Full name: tetratricopeptide repeat domain 25 | Alias Symbol: DKFZP434H0115 | ||
| Type: protein-coding gene | Cytoband: 17q21.2 | ||
| Entrez ID: 83538 | HGNC ID: HGNC:25280 | Ensembl Gene: ENSG00000204815 | OMIM ID: 617095 |
| Drug and gene relationship at DGIdb | |||
Expression of TTC25:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TTC25 | 83538 | 223924_at | 0.1082 | 0.6354 | |
| GSE26886 | TTC25 | 83538 | 223924_at | 0.6689 | 0.0003 | |
| GSE45670 | TTC25 | 83538 | 223924_at | -0.0768 | 0.4606 | |
| GSE53622 | TTC25 | 83538 | 52369 | 0.2173 | 0.0003 | |
| GSE53624 | TTC25 | 83538 | 52369 | 0.2404 | 0.0040 | |
| GSE63941 | TTC25 | 83538 | 223924_at | -0.0869 | 0.7502 | |
| GSE77861 | TTC25 | 83538 | 223924_at | 0.0187 | 0.9093 | |
| GSE97050 | TTC25 | 83538 | A_23_P73150 | -0.2530 | 0.3880 | |
| SRP133303 | TTC25 | 83538 | RNAseq | 0.7545 | 0.0106 | |
| SRP159526 | TTC25 | 83538 | RNAseq | 1.5920 | 0.0319 | |
| TCGA | TTC25 | 83538 | RNAseq | -0.0349 | 0.9182 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by TTC25 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TTC25:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TTC25 | 83538 | 6 | 2 | 22 | |
| GSE20123 | TTC25 | 83538 | 6 | 2 | 22 | |
| GSE43470 | TTC25 | 83538 | 1 | 2 | 40 | |
| GSE46452 | TTC25 | 83538 | 34 | 0 | 25 | |
| GSE47630 | TTC25 | 83538 | 8 | 1 | 31 | |
| GSE54993 | TTC25 | 83538 | 3 | 4 | 63 | |
| GSE54994 | TTC25 | 83538 | 8 | 5 | 40 | |
| GSE60625 | TTC25 | 83538 | 4 | 0 | 7 | |
| GSE74703 | TTC25 | 83538 | 1 | 1 | 34 | |
| GSE74704 | TTC25 | 83538 | 4 | 1 | 15 | |
| TCGA | TTC25 | 83538 | 23 | 6 | 67 |
Total number of gains: 98; Total number of losses: 24; Total Number of normals: 366.
Somatic mutations of TTC25:
Generating mutation plots.
Highly correlated genes for TTC25:
Showing top 20/99 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TTC25 | C19orf25 | 0.724212 | 3 | 0 | 3 |
| TTC25 | JAKMIP2 | 0.708091 | 3 | 0 | 3 |
| TTC25 | HSD17B14 | 0.707448 | 3 | 0 | 3 |
| TTC25 | LONP1 | 0.705225 | 3 | 0 | 3 |
| TTC25 | CCDC42 | 0.698089 | 3 | 0 | 3 |
| TTC25 | ZNF639 | 0.69123 | 3 | 0 | 3 |
| TTC25 | CYP11B1 | 0.682793 | 3 | 0 | 3 |
| TTC25 | FBRSL1 | 0.679894 | 3 | 0 | 3 |
| TTC25 | CRYGC | 0.671244 | 3 | 0 | 3 |
| TTC25 | CDH23 | 0.662805 | 4 | 0 | 3 |
| TTC25 | ANKRD45 | 0.657927 | 3 | 0 | 3 |
| TTC25 | NTNG2 | 0.655893 | 4 | 0 | 3 |
| TTC25 | MBD6 | 0.651454 | 3 | 0 | 3 |
| TTC25 | NPPB | 0.648759 | 3 | 0 | 3 |
| TTC25 | TRIM46 | 0.647876 | 3 | 0 | 3 |
| TTC25 | HTRA4 | 0.647492 | 3 | 0 | 3 |
| TTC25 | SPATA2L | 0.646411 | 3 | 0 | 3 |
| TTC25 | MDC1 | 0.644435 | 4 | 0 | 3 |
| TTC25 | ZCWPW1 | 0.643414 | 4 | 0 | 3 |
| TTC25 | AGO1 | 0.643343 | 3 | 0 | 3 |
For details and further investigation, click here
