| Full name: argonaute RISC component 1 | Alias Symbol: hAGO1 | ||
| Type: protein-coding gene | Cytoband: 1p34.3 | ||
| Entrez ID: 26523 | HGNC ID: HGNC:3262 | Ensembl Gene: ENSG00000092847 | OMIM ID: 606228 |
Expression of AGO1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | AGO1 | 26523 | 218287_s_at | 0.5470 | 0.1673 | |
| GSE20347 | AGO1 | 26523 | 218287_s_at | 0.3944 | 0.0054 | |
| GSE23400 | AGO1 | 26523 | 218287_s_at | 0.1881 | 0.0002 | |
| GSE26886 | AGO1 | 26523 | 218287_s_at | 0.6620 | 0.0003 | |
| GSE29001 | AGO1 | 26523 | 218287_s_at | 0.2116 | 0.3107 | |
| GSE38129 | AGO1 | 26523 | 218287_s_at | 0.2713 | 0.0164 | |
| GSE45670 | AGO1 | 26523 | 218287_s_at | 0.2306 | 0.1241 | |
| GSE53622 | AGO1 | 26523 | 41508 | -0.0039 | 0.9622 | |
| GSE53624 | AGO1 | 26523 | 41508 | 0.3298 | 0.0000 | |
| GSE63941 | AGO1 | 26523 | 218287_s_at | -0.5362 | 0.2660 | |
| GSE77861 | AGO1 | 26523 | 218287_s_at | 0.1780 | 0.5105 | |
| SRP007169 | AGO1 | 26523 | RNAseq | 1.4301 | 0.0009 | |
| SRP008496 | AGO1 | 26523 | RNAseq | 1.0262 | 0.0003 | |
| SRP064894 | AGO1 | 26523 | RNAseq | 0.5059 | 0.0008 | |
| SRP133303 | AGO1 | 26523 | RNAseq | 0.2210 | 0.2004 | |
| SRP159526 | AGO1 | 26523 | RNAseq | 0.6025 | 0.0602 | |
| SRP193095 | AGO1 | 26523 | RNAseq | 0.3077 | 0.0117 | |
| SRP219564 | AGO1 | 26523 | RNAseq | -0.0415 | 0.8893 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by AGO1 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of AGO1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | AGO1 | 26523 | 2 | 5 | 23 | |
| GSE20123 | AGO1 | 26523 | 2 | 4 | 24 | |
| GSE43470 | AGO1 | 26523 | 7 | 2 | 34 | |
| GSE46452 | AGO1 | 26523 | 4 | 1 | 54 | |
| GSE47630 | AGO1 | 26523 | 8 | 3 | 29 | |
| GSE54993 | AGO1 | 26523 | 1 | 1 | 68 | |
| GSE54994 | AGO1 | 26523 | 11 | 2 | 40 | |
| GSE60625 | AGO1 | 26523 | 0 | 0 | 11 | |
| GSE74703 | AGO1 | 26523 | 6 | 1 | 29 | |
| GSE74704 | AGO1 | 26523 | 1 | 0 | 19 | |
| TCGA | AGO1 | 26523 | 11 | 19 | 66 |
Total number of gains: 53; Total number of losses: 38; Total Number of normals: 397.
Somatic mutations of AGO1:
Generating mutation plots.
Highly correlated genes for AGO1:
Showing top 20/299 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| AGO1 | CPT1C | 0.736861 | 3 | 0 | 3 |
| AGO1 | ZNF697 | 0.719896 | 3 | 0 | 3 |
| AGO1 | METTL23 | 0.709938 | 3 | 0 | 3 |
| AGO1 | BET1 | 0.669846 | 3 | 0 | 3 |
| AGO1 | ORC1 | 0.664514 | 5 | 0 | 4 |
| AGO1 | MRPS26 | 0.657789 | 3 | 0 | 3 |
| AGO1 | FNIP2 | 0.656419 | 3 | 0 | 3 |
| AGO1 | YBX1 | 0.649096 | 5 | 0 | 4 |
| AGO1 | PLAGL2 | 0.644424 | 3 | 0 | 3 |
| AGO1 | TTC25 | 0.643343 | 3 | 0 | 3 |
| AGO1 | MAK16 | 0.636424 | 3 | 0 | 3 |
| AGO1 | CCDC24 | 0.633462 | 3 | 0 | 3 |
| AGO1 | VPS33A | 0.628577 | 3 | 0 | 3 |
| AGO1 | PSMB2 | 0.6276 | 8 | 0 | 7 |
| AGO1 | NUP160 | 0.625431 | 5 | 0 | 4 |
| AGO1 | TTC4 | 0.619212 | 7 | 0 | 5 |
| AGO1 | PXYLP1 | 0.618473 | 3 | 0 | 3 |
| AGO1 | COA7 | 0.617524 | 4 | 0 | 3 |
| AGO1 | CHCHD6 | 0.61605 | 4 | 0 | 3 |
| AGO1 | SDHAF1 | 0.615863 | 4 | 0 | 3 |
For details and further investigation, click here
