| Full name: tubulin tyrosine ligase like 6 | Alias Symbol: FLJ35808 | ||
| Type: protein-coding gene | Cytoband: 17q21.32 | ||
| Entrez ID: 284076 | HGNC ID: HGNC:26664 | Ensembl Gene: ENSG00000170703 | OMIM ID: 610849 |
| Drug and gene relationship at DGIdb | |||
Expression of TTLL6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TTLL6 | 284076 | 230924_at | -0.1066 | 0.6692 | |
| GSE26886 | TTLL6 | 284076 | 230924_at | -0.0387 | 0.7646 | |
| GSE45670 | TTLL6 | 284076 | 230924_at | -0.0230 | 0.8350 | |
| GSE53622 | TTLL6 | 284076 | 103211 | 0.3351 | 0.1022 | |
| GSE53624 | TTLL6 | 284076 | 103211 | 0.1812 | 0.1488 | |
| GSE63941 | TTLL6 | 284076 | 230924_at | 0.2849 | 0.1174 | |
| GSE77861 | TTLL6 | 284076 | 230924_at | -0.0973 | 0.3916 | |
| TCGA | TTLL6 | 284076 | RNAseq | -1.9650 | 0.0740 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TTLL6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TTLL6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TTLL6 | 284076 | 6 | 2 | 22 | |
| GSE20123 | TTLL6 | 284076 | 6 | 2 | 22 | |
| GSE43470 | TTLL6 | 284076 | 3 | 0 | 40 | |
| GSE46452 | TTLL6 | 284076 | 32 | 0 | 27 | |
| GSE47630 | TTLL6 | 284076 | 9 | 0 | 31 | |
| GSE54993 | TTLL6 | 284076 | 2 | 4 | 64 | |
| GSE54994 | TTLL6 | 284076 | 10 | 6 | 37 | |
| GSE60625 | TTLL6 | 284076 | 4 | 0 | 7 | |
| GSE74703 | TTLL6 | 284076 | 3 | 0 | 33 | |
| GSE74704 | TTLL6 | 284076 | 4 | 1 | 15 | |
| TCGA | TTLL6 | 284076 | 27 | 6 | 63 |
Total number of gains: 106; Total number of losses: 21; Total Number of normals: 361.
Somatic mutations of TTLL6:
Generating mutation plots.
Highly correlated genes for TTLL6:
Showing top 20/78 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TTLL6 | BRSK2 | 0.701592 | 3 | 0 | 3 |
| TTLL6 | OR1A2 | 0.700613 | 3 | 0 | 3 |
| TTLL6 | FSCN3 | 0.674359 | 3 | 0 | 3 |
| TTLL6 | EPX | 0.664016 | 3 | 0 | 3 |
| TTLL6 | CASC17 | 0.659184 | 3 | 0 | 3 |
| TTLL6 | SCGB2B2 | 0.65171 | 3 | 0 | 3 |
| TTLL6 | ITPKB-IT1 | 0.651572 | 3 | 0 | 3 |
| TTLL6 | ALPI | 0.645733 | 3 | 0 | 3 |
| TTLL6 | CD300LB | 0.642765 | 3 | 0 | 3 |
| TTLL6 | C19orf84 | 0.642455 | 3 | 0 | 3 |
| TTLL6 | SOX1 | 0.640866 | 3 | 0 | 3 |
| TTLL6 | ADAM30 | 0.637086 | 3 | 0 | 3 |
| TTLL6 | GLOD5 | 0.634258 | 3 | 0 | 3 |
| TTLL6 | GSX1 | 0.625948 | 4 | 0 | 3 |
| TTLL6 | MAP3K10 | 0.619005 | 3 | 0 | 3 |
| TTLL6 | UTS2R | 0.61576 | 4 | 0 | 3 |
| TTLL6 | LINC01312 | 0.613057 | 3 | 0 | 3 |
| TTLL6 | CCDC154 | 0.611583 | 3 | 0 | 3 |
| TTLL6 | PSAPL1 | 0.599068 | 3 | 0 | 3 |
| TTLL6 | LINC00408 | 0.598654 | 3 | 0 | 3 |
For details and further investigation, click here
