| Full name: prosaposin like 1 (gene/pseudogene) | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 4p16.1 | ||
| Entrez ID: 768239 | HGNC ID: HGNC:33131 | Ensembl Gene: ENSG00000178597 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of PSAPL1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PSAPL1 | 768239 | 1564333_a_at | 0.0590 | 0.8797 | |
| GSE26886 | PSAPL1 | 768239 | 1564333_a_at | 0.0410 | 0.8635 | |
| GSE45670 | PSAPL1 | 768239 | 1564333_a_at | -0.0190 | 0.8948 | |
| GSE53622 | PSAPL1 | 768239 | 42004 | 0.2345 | 0.5329 | |
| GSE53624 | PSAPL1 | 768239 | 42004 | 0.4837 | 0.0959 | |
| GSE63941 | PSAPL1 | 768239 | 1564333_a_at | 0.4659 | 0.1870 | |
| GSE77861 | PSAPL1 | 768239 | 1564333_a_at | -0.1535 | 0.1524 | |
| SRP133303 | PSAPL1 | 768239 | RNAseq | 0.5547 | 0.1561 | |
| TCGA | PSAPL1 | 768239 | RNAseq | -2.5690 | 0.0001 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by PSAPL1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PSAPL1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PSAPL1 | 768239 | 0 | 18 | 12 | |
| GSE20123 | PSAPL1 | 768239 | 0 | 18 | 12 | |
| GSE43470 | PSAPL1 | 768239 | 0 | 17 | 26 | |
| GSE46452 | PSAPL1 | 768239 | 1 | 36 | 22 | |
| GSE47630 | PSAPL1 | 768239 | 1 | 19 | 20 | |
| GSE54993 | PSAPL1 | 768239 | 10 | 0 | 60 | |
| GSE54994 | PSAPL1 | 768239 | 3 | 12 | 38 | |
| GSE60625 | PSAPL1 | 768239 | 0 | 0 | 11 | |
| GSE74703 | PSAPL1 | 768239 | 0 | 13 | 23 | |
| GSE74704 | PSAPL1 | 768239 | 0 | 10 | 10 | |
| TCGA | PSAPL1 | 768239 | 7 | 47 | 42 |
Total number of gains: 22; Total number of losses: 190; Total Number of normals: 276.
Somatic mutations of PSAPL1:
Generating mutation plots.
Highly correlated genes for PSAPL1:
Showing top 20/31 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PSAPL1 | CTRB2 | 0.6736 | 3 | 0 | 3 |
| PSAPL1 | FFAR2 | 0.668064 | 3 | 0 | 3 |
| PSAPL1 | CD5L | 0.640006 | 3 | 0 | 3 |
| PSAPL1 | RIPK4 | 0.619102 | 3 | 0 | 3 |
| PSAPL1 | MYO1A | 0.618785 | 3 | 0 | 3 |
| PSAPL1 | ACTL7A | 0.615539 | 3 | 0 | 3 |
| PSAPL1 | VGLL2 | 0.614473 | 4 | 0 | 4 |
| PSAPL1 | PRDM14 | 0.613109 | 3 | 0 | 3 |
| PSAPL1 | ATP1A3 | 0.601127 | 3 | 0 | 3 |
| PSAPL1 | TTLL6 | 0.599068 | 3 | 0 | 3 |
| PSAPL1 | BMP15 | 0.579757 | 3 | 0 | 3 |
| PSAPL1 | IGSF10 | 0.579553 | 3 | 0 | 3 |
| PSAPL1 | ABHD1 | 0.5755 | 3 | 0 | 3 |
| PSAPL1 | CPN2 | 0.573749 | 3 | 0 | 3 |
| PSAPL1 | KRTAP8-1 | 0.572091 | 4 | 0 | 3 |
| PSAPL1 | CA7 | 0.569791 | 4 | 0 | 3 |
| PSAPL1 | CAPSL | 0.567256 | 4 | 0 | 3 |
| PSAPL1 | TSPAN11 | 0.566985 | 4 | 0 | 4 |
| PSAPL1 | ASB10 | 0.557114 | 4 | 0 | 4 |
| PSAPL1 | ACVR1B | 0.549296 | 3 | 0 | 3 |
For details and further investigation, click here
