| Full name: opsin 4 | Alias Symbol: MOP|melanopsin | ||
| Type: protein-coding gene | Cytoband: 10q23.2 | ||
| Entrez ID: 94233 | HGNC ID: HGNC:14449 | Ensembl Gene: ENSG00000122375 | OMIM ID: 606665 |
| Drug and gene relationship at DGIdb | |||
Expression of OPN4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | OPN4 | 94233 | 234226_at | -0.0918 | 0.7377 | |
| GSE26886 | OPN4 | 94233 | 234226_at | 0.1038 | 0.4311 | |
| GSE45670 | OPN4 | 94233 | 234226_at | 0.0715 | 0.5436 | |
| GSE53622 | OPN4 | 94233 | 10721 | 0.1228 | 0.2394 | |
| GSE53624 | OPN4 | 94233 | 10721 | 0.0614 | 0.5489 | |
| GSE63941 | OPN4 | 94233 | 234226_at | 0.1368 | 0.3329 | |
| GSE77861 | OPN4 | 94233 | 234226_at | -0.1556 | 0.0589 | |
| GSE97050 | OPN4 | 94233 | A_23_P24234 | -0.1827 | 0.5016 | |
| TCGA | OPN4 | 94233 | RNAseq | -0.3224 | 0.7802 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by OPN4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of OPN4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | OPN4 | 94233 | 1 | 7 | 22 | |
| GSE20123 | OPN4 | 94233 | 1 | 6 | 23 | |
| GSE43470 | OPN4 | 94233 | 1 | 6 | 36 | |
| GSE46452 | OPN4 | 94233 | 0 | 11 | 48 | |
| GSE47630 | OPN4 | 94233 | 2 | 14 | 24 | |
| GSE54993 | OPN4 | 94233 | 7 | 0 | 63 | |
| GSE54994 | OPN4 | 94233 | 1 | 12 | 40 | |
| GSE60625 | OPN4 | 94233 | 0 | 0 | 11 | |
| GSE74703 | OPN4 | 94233 | 1 | 4 | 31 | |
| GSE74704 | OPN4 | 94233 | 0 | 4 | 16 | |
| TCGA | OPN4 | 94233 | 7 | 27 | 62 |
Total number of gains: 21; Total number of losses: 91; Total Number of normals: 376.
Somatic mutations of OPN4:
Generating mutation plots.
Highly correlated genes for OPN4:
Showing top 20/385 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| OPN4 | OTOG | 0.812143 | 3 | 0 | 3 |
| OPN4 | SLC26A1 | 0.811817 | 3 | 0 | 3 |
| OPN4 | KRTAP10-12 | 0.797833 | 3 | 0 | 3 |
| OPN4 | YY2 | 0.788369 | 3 | 0 | 3 |
| OPN4 | PRSS38 | 0.774994 | 3 | 0 | 3 |
| OPN4 | PRAMEF5 | 0.771878 | 3 | 0 | 3 |
| OPN4 | GRIK4 | 0.770047 | 3 | 0 | 3 |
| OPN4 | OR2B11 | 0.77002 | 3 | 0 | 3 |
| OPN4 | PAQR6 | 0.762973 | 4 | 0 | 4 |
| OPN4 | TUBA8 | 0.762124 | 3 | 0 | 3 |
| OPN4 | PLA2G2C | 0.759263 | 3 | 0 | 3 |
| OPN4 | SERPINA10 | 0.758396 | 3 | 0 | 3 |
| OPN4 | KLHL10 | 0.756114 | 3 | 0 | 3 |
| OPN4 | OR2T1 | 0.753491 | 3 | 0 | 3 |
| OPN4 | DHRS7C | 0.75097 | 3 | 0 | 3 |
| OPN4 | NRSN1 | 0.745607 | 3 | 0 | 3 |
| OPN4 | GPHA2 | 0.742607 | 3 | 0 | 3 |
| OPN4 | STRC | 0.742579 | 3 | 0 | 3 |
| OPN4 | TAAR5 | 0.741795 | 3 | 0 | 3 |
| OPN4 | RASGEF1C | 0.738953 | 3 | 0 | 3 |
For details and further investigation, click here
