| Full name: CDC42 effector protein 2 | Alias Symbol: CEP2|BORG1 | ||
| Type: protein-coding gene | Cytoband: 11q13.1 | ||
| Entrez ID: 10435 | HGNC ID: HGNC:16263 | Ensembl Gene: ENSG00000149798 | OMIM ID: 606132 |
| Drug and gene relationship at DGIdb | |||
Expression of CDC42EP2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CDC42EP2 | 10435 | 209850_s_at | -0.2315 | 0.7131 | |
| GSE20347 | CDC42EP2 | 10435 | 209850_s_at | 0.0678 | 0.3979 | |
| GSE23400 | CDC42EP2 | 10435 | 209850_s_at | -0.0573 | 0.2320 | |
| GSE26886 | CDC42EP2 | 10435 | 209850_s_at | 0.7004 | 0.0000 | |
| GSE29001 | CDC42EP2 | 10435 | 209850_s_at | 0.0209 | 0.9283 | |
| GSE38129 | CDC42EP2 | 10435 | 209850_s_at | -0.3849 | 0.0079 | |
| GSE45670 | CDC42EP2 | 10435 | 209850_s_at | 0.1253 | 0.3004 | |
| GSE63941 | CDC42EP2 | 10435 | 209850_s_at | -0.6595 | 0.0590 | |
| GSE77861 | CDC42EP2 | 10435 | 209850_s_at | 0.0540 | 0.7607 | |
| GSE97050 | CDC42EP2 | 10435 | A_23_P1602 | -0.3322 | 0.2027 | |
| SRP007169 | CDC42EP2 | 10435 | RNAseq | 0.4470 | 0.4647 | |
| SRP008496 | CDC42EP2 | 10435 | RNAseq | 0.2383 | 0.5350 | |
| SRP064894 | CDC42EP2 | 10435 | RNAseq | -0.5306 | 0.0787 | |
| SRP133303 | CDC42EP2 | 10435 | RNAseq | -0.2397 | 0.4102 | |
| SRP159526 | CDC42EP2 | 10435 | RNAseq | -0.1922 | 0.5355 | |
| SRP193095 | CDC42EP2 | 10435 | RNAseq | 1.2100 | 0.0001 | |
| SRP219564 | CDC42EP2 | 10435 | RNAseq | -0.5934 | 0.4655 | |
| TCGA | CDC42EP2 | 10435 | RNAseq | -0.1223 | 0.1643 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by CDC42EP2 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of CDC42EP2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CDC42EP2 | 10435 | 7 | 6 | 17 | |
| GSE20123 | CDC42EP2 | 10435 | 7 | 6 | 17 | |
| GSE43470 | CDC42EP2 | 10435 | 4 | 1 | 38 | |
| GSE46452 | CDC42EP2 | 10435 | 11 | 3 | 45 | |
| GSE47630 | CDC42EP2 | 10435 | 7 | 5 | 28 | |
| GSE54993 | CDC42EP2 | 10435 | 3 | 0 | 67 | |
| GSE54994 | CDC42EP2 | 10435 | 6 | 5 | 42 | |
| GSE60625 | CDC42EP2 | 10435 | 0 | 3 | 8 | |
| GSE74703 | CDC42EP2 | 10435 | 3 | 0 | 33 | |
| GSE74704 | CDC42EP2 | 10435 | 5 | 4 | 11 | |
| TCGA | CDC42EP2 | 10435 | 23 | 7 | 66 |
Total number of gains: 76; Total number of losses: 40; Total Number of normals: 372.
Somatic mutations of CDC42EP2:
Generating mutation plots.
Highly correlated genes for CDC42EP2:
Showing top 20/344 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CDC42EP2 | HGD | 0.770517 | 3 | 0 | 3 |
| CDC42EP2 | HRC | 0.769997 | 4 | 0 | 4 |
| CDC42EP2 | COL24A1 | 0.757967 | 3 | 0 | 3 |
| CDC42EP2 | CA4 | 0.754706 | 4 | 0 | 3 |
| CDC42EP2 | MUC8 | 0.752498 | 3 | 0 | 3 |
| CDC42EP2 | SLN | 0.745896 | 3 | 0 | 3 |
| CDC42EP2 | ZNF205 | 0.742422 | 3 | 0 | 3 |
| CDC42EP2 | SHISA3 | 0.734243 | 3 | 0 | 3 |
| CDC42EP2 | OR1F1 | 0.734094 | 4 | 0 | 3 |
| CDC42EP2 | SCN9A | 0.733989 | 3 | 0 | 3 |
| CDC42EP2 | PARP10 | 0.732496 | 3 | 0 | 3 |
| CDC42EP2 | FLCN | 0.731101 | 3 | 0 | 3 |
| CDC42EP2 | SCGN | 0.726278 | 4 | 0 | 3 |
| CDC42EP2 | PICK1 | 0.725689 | 3 | 0 | 3 |
| CDC42EP2 | GLI1 | 0.724658 | 3 | 0 | 3 |
| CDC42EP2 | GRIK3 | 0.724179 | 3 | 0 | 3 |
| CDC42EP2 | DOHH | 0.72213 | 3 | 0 | 3 |
| CDC42EP2 | TCEAL7 | 0.721029 | 3 | 0 | 3 |
| CDC42EP2 | TNN | 0.720072 | 3 | 0 | 3 |
| CDC42EP2 | ZNF781 | 0.719369 | 3 | 0 | 3 |
For details and further investigation, click here
