| Full name: zinc finger protein 491 | Alias Symbol: FLJ34791 | ||
| Type: protein-coding gene | Cytoband: 19p13.2 | ||
| Entrez ID: 126069 | HGNC ID: HGNC:23706 | Ensembl Gene: ENSG00000177599 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of ZNF491:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZNF491 | 126069 | 1562211_a_at | -0.0418 | 0.9229 | |
| GSE26886 | ZNF491 | 126069 | 1562211_a_at | -0.2183 | 0.0785 | |
| GSE45670 | ZNF491 | 126069 | 1562211_a_at | -0.1309 | 0.2317 | |
| GSE53622 | ZNF491 | 126069 | 43947 | -0.1573 | 0.2032 | |
| GSE53624 | ZNF491 | 126069 | 43947 | -0.1895 | 0.0279 | |
| GSE63941 | ZNF491 | 126069 | 1562211_a_at | -0.3842 | 0.0226 | |
| GSE77861 | ZNF491 | 126069 | 1562211_a_at | -0.1799 | 0.1091 | |
| GSE97050 | ZNF491 | 126069 | A_23_P410725 | -0.1157 | 0.6284 | |
| SRP064894 | ZNF491 | 126069 | RNAseq | -0.0848 | 0.7501 | |
| SRP133303 | ZNF491 | 126069 | RNAseq | -0.1639 | 0.3832 | |
| SRP159526 | ZNF491 | 126069 | RNAseq | 0.1897 | 0.7191 | |
| SRP193095 | ZNF491 | 126069 | RNAseq | -0.2578 | 0.0099 | |
| SRP219564 | ZNF491 | 126069 | RNAseq | 0.1897 | 0.6532 | |
| TCGA | ZNF491 | 126069 | RNAseq | -1.2719 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by ZNF491 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZNF491:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZNF491 | 126069 | 4 | 2 | 24 | |
| GSE20123 | ZNF491 | 126069 | 3 | 1 | 26 | |
| GSE43470 | ZNF491 | 126069 | 2 | 6 | 35 | |
| GSE46452 | ZNF491 | 126069 | 47 | 1 | 11 | |
| GSE47630 | ZNF491 | 126069 | 4 | 7 | 29 | |
| GSE54993 | ZNF491 | 126069 | 16 | 3 | 51 | |
| GSE54994 | ZNF491 | 126069 | 6 | 13 | 34 | |
| GSE60625 | ZNF491 | 126069 | 9 | 0 | 2 | |
| GSE74703 | ZNF491 | 126069 | 2 | 4 | 30 | |
| GSE74704 | ZNF491 | 126069 | 0 | 1 | 19 | |
| TCGA | ZNF491 | 126069 | 15 | 13 | 68 |
Total number of gains: 108; Total number of losses: 51; Total Number of normals: 329.
Somatic mutations of ZNF491:
Generating mutation plots.
Highly correlated genes for ZNF491:
Showing top 20/93 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZNF491 | HCRT | 0.787576 | 3 | 0 | 3 |
| ZNF491 | CRYGC | 0.785167 | 3 | 0 | 3 |
| ZNF491 | INSC | 0.76621 | 3 | 0 | 3 |
| ZNF491 | ASTN1 | 0.761212 | 3 | 0 | 3 |
| ZNF491 | OLIG3 | 0.74992 | 3 | 0 | 3 |
| ZNF491 | ANKRD53 | 0.748465 | 3 | 0 | 3 |
| ZNF491 | AMHR2 | 0.730389 | 3 | 0 | 3 |
| ZNF491 | AQP8 | 0.726787 | 3 | 0 | 3 |
| ZNF491 | TUBA8 | 0.724378 | 3 | 0 | 3 |
| ZNF491 | NKX6-3 | 0.720231 | 3 | 0 | 3 |
| ZNF491 | KCNJ13 | 0.70463 | 3 | 0 | 3 |
| ZNF491 | GRIK3 | 0.702578 | 3 | 0 | 3 |
| ZNF491 | RAX | 0.698585 | 3 | 0 | 3 |
| ZNF491 | C11orf86 | 0.698048 | 3 | 0 | 3 |
| ZNF491 | PENK | 0.69705 | 4 | 0 | 4 |
| ZNF491 | SHISA3 | 0.690075 | 3 | 0 | 3 |
| ZNF491 | CA4 | 0.677156 | 5 | 0 | 4 |
| ZNF491 | OR12D3 | 0.675443 | 3 | 0 | 3 |
| ZNF491 | CACNA1A | 0.669761 | 3 | 0 | 3 |
| ZNF491 | SLC6A13 | 0.667987 | 3 | 0 | 3 |
For details and further investigation, click here
