| Full name: ATP binding cassette subfamily A member 7 | Alias Symbol: ABCX | ||
| Type: protein-coding gene | Cytoband: 19p13.3 | ||
| Entrez ID: 10347 | HGNC ID: HGNC:37 | Ensembl Gene: ENSG00000064687 | OMIM ID: 605414 |
| Drug and gene relationship at DGIdb | |||
Expression of ABCA7:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ABCA7 | 10347 | 219577_s_at | 0.2389 | 0.6425 | |
| GSE20347 | ABCA7 | 10347 | 219577_s_at | -0.2560 | 0.0445 | |
| GSE23400 | ABCA7 | 10347 | 219577_s_at | -0.2930 | 0.0000 | |
| GSE26886 | ABCA7 | 10347 | 219577_s_at | -0.0675 | 0.7983 | |
| GSE29001 | ABCA7 | 10347 | 219577_s_at | -0.3953 | 0.2171 | |
| GSE38129 | ABCA7 | 10347 | 219577_s_at | -0.1397 | 0.3704 | |
| GSE45670 | ABCA7 | 10347 | 219577_s_at | 0.5948 | 0.0013 | |
| GSE53622 | ABCA7 | 10347 | 32198 | -0.3090 | 0.0000 | |
| GSE53624 | ABCA7 | 10347 | 32198 | -0.2969 | 0.0001 | |
| GSE63941 | ABCA7 | 10347 | 219577_s_at | 0.1437 | 0.7084 | |
| GSE77861 | ABCA7 | 10347 | 219577_s_at | -0.1518 | 0.3392 | |
| GSE97050 | ABCA7 | 10347 | A_33_P3374623 | 0.2244 | 0.4167 | |
| SRP007169 | ABCA7 | 10347 | RNAseq | -0.1150 | 0.8350 | |
| SRP064894 | ABCA7 | 10347 | RNAseq | 0.3712 | 0.2584 | |
| SRP133303 | ABCA7 | 10347 | RNAseq | -0.3989 | 0.1338 | |
| SRP159526 | ABCA7 | 10347 | RNAseq | -0.6178 | 0.0696 | |
| SRP193095 | ABCA7 | 10347 | RNAseq | -0.0769 | 0.7375 | |
| SRP219564 | ABCA7 | 10347 | RNAseq | -0.2296 | 0.6222 | |
| TCGA | ABCA7 | 10347 | RNAseq | -0.0099 | 0.9203 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ABCA7 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ABCA7:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ABCA7 | 10347 | 4 | 6 | 20 | |
| GSE20123 | ABCA7 | 10347 | 4 | 5 | 21 | |
| GSE43470 | ABCA7 | 10347 | 1 | 9 | 33 | |
| GSE46452 | ABCA7 | 10347 | 47 | 1 | 11 | |
| GSE47630 | ABCA7 | 10347 | 5 | 7 | 28 | |
| GSE54993 | ABCA7 | 10347 | 13 | 4 | 53 | |
| GSE54994 | ABCA7 | 10347 | 8 | 15 | 30 | |
| GSE60625 | ABCA7 | 10347 | 9 | 0 | 2 | |
| GSE74703 | ABCA7 | 10347 | 1 | 7 | 28 | |
| GSE74704 | ABCA7 | 10347 | 3 | 3 | 14 | |
| TCGA | ABCA7 | 10347 | 8 | 25 | 63 |
Total number of gains: 103; Total number of losses: 82; Total Number of normals: 303.
Somatic mutations of ABCA7:
Generating mutation plots.
Highly correlated genes for ABCA7:
Showing top 20/222 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ABCA7 | ZNF283 | 0.742321 | 3 | 0 | 3 |
| ABCA7 | HDAC8 | 0.73656 | 3 | 0 | 3 |
| ABCA7 | XRCC2 | 0.731162 | 3 | 0 | 3 |
| ABCA7 | CPNE9 | 0.722375 | 3 | 0 | 3 |
| ABCA7 | TUBGCP6 | 0.718971 | 4 | 0 | 4 |
| ABCA7 | ZAN | 0.704716 | 4 | 0 | 3 |
| ABCA7 | CDC42BPB | 0.702675 | 3 | 0 | 3 |
| ABCA7 | EPHA10 | 0.695348 | 3 | 0 | 3 |
| ABCA7 | SLC2A11 | 0.688711 | 3 | 0 | 3 |
| ABCA7 | ZBTB46 | 0.684487 | 3 | 0 | 3 |
| ABCA7 | CABP2 | 0.667846 | 3 | 0 | 3 |
| ABCA7 | TERT | 0.660437 | 4 | 0 | 3 |
| ABCA7 | SETD1B | 0.65736 | 3 | 0 | 3 |
| ABCA7 | CD52 | 0.656638 | 3 | 0 | 3 |
| ABCA7 | POLL | 0.652639 | 6 | 0 | 4 |
| ABCA7 | B3GNTL1 | 0.651477 | 3 | 0 | 3 |
| ABCA7 | ATAD3C | 0.649692 | 4 | 0 | 4 |
| ABCA7 | BCL2L10 | 0.649064 | 3 | 0 | 3 |
| ABCA7 | MBD6 | 0.646951 | 6 | 0 | 5 |
| ABCA7 | CDK16 | 0.646527 | 4 | 0 | 3 |
For details and further investigation, click here
