| Full name: DBF4 zinc finger B | Alias Symbol: FLJ13087|DRF1|ASKL1|chifb|ZDBF1B | ||
| Type: protein-coding gene | Cytoband: 17q21.31 | ||
| Entrez ID: 80174 | HGNC ID: HGNC:17883 | Ensembl Gene: ENSG00000161692 | OMIM ID: 611661 |
| Drug and gene relationship at DGIdb | |||
Expression of DBF4B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DBF4B | 80174 | 238508_at | 0.5104 | 0.0780 | |
| GSE20347 | DBF4B | 80174 | 206661_at | 0.1039 | 0.3073 | |
| GSE23400 | DBF4B | 80174 | 206661_at | -0.0529 | 0.1372 | |
| GSE26886 | DBF4B | 80174 | 1555378_at | -0.0141 | 0.9156 | |
| GSE29001 | DBF4B | 80174 | 206661_at | -0.0580 | 0.6487 | |
| GSE38129 | DBF4B | 80174 | 206661_at | 0.1327 | 0.1486 | |
| GSE45670 | DBF4B | 80174 | 1555378_at | 0.0119 | 0.9361 | |
| GSE53622 | DBF4B | 80174 | 173452 | 0.9881 | 0.0000 | |
| GSE53624 | DBF4B | 80174 | 173452 | 0.9168 | 0.0000 | |
| GSE63941 | DBF4B | 80174 | 238508_at | 0.8359 | 0.0506 | |
| GSE77861 | DBF4B | 80174 | 1555378_at | -0.0879 | 0.4878 | |
| GSE97050 | DBF4B | 80174 | A_23_P38328 | -0.3140 | 0.3353 | |
| SRP007169 | DBF4B | 80174 | RNAseq | 2.7429 | 0.0000 | |
| SRP064894 | DBF4B | 80174 | RNAseq | 1.2619 | 0.0000 | |
| SRP133303 | DBF4B | 80174 | RNAseq | 0.9962 | 0.0000 | |
| SRP159526 | DBF4B | 80174 | RNAseq | 1.2375 | 0.0017 | |
| SRP193095 | DBF4B | 80174 | RNAseq | 1.1576 | 0.0000 | |
| SRP219564 | DBF4B | 80174 | RNAseq | 0.9199 | 0.0136 | |
| TCGA | DBF4B | 80174 | RNAseq | 0.5105 | 0.0000 |
Upregulated datasets: 4; Downregulated datasets: 0.
Survival by DBF4B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DBF4B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DBF4B | 80174 | 6 | 2 | 22 | |
| GSE20123 | DBF4B | 80174 | 6 | 2 | 22 | |
| GSE43470 | DBF4B | 80174 | 1 | 2 | 40 | |
| GSE46452 | DBF4B | 80174 | 32 | 0 | 27 | |
| GSE47630 | DBF4B | 80174 | 9 | 0 | 31 | |
| GSE54993 | DBF4B | 80174 | 3 | 4 | 63 | |
| GSE54994 | DBF4B | 80174 | 8 | 5 | 40 | |
| GSE60625 | DBF4B | 80174 | 4 | 0 | 7 | |
| GSE74703 | DBF4B | 80174 | 1 | 1 | 34 | |
| GSE74704 | DBF4B | 80174 | 4 | 1 | 15 | |
| TCGA | DBF4B | 80174 | 27 | 6 | 63 |
Total number of gains: 101; Total number of losses: 23; Total Number of normals: 364.
Somatic mutations of DBF4B:
Generating mutation plots.
Highly correlated genes for DBF4B:
Showing top 20/284 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DBF4B | UBE2S | 0.795839 | 3 | 0 | 3 |
| DBF4B | RFX8 | 0.758307 | 3 | 0 | 3 |
| DBF4B | WDR90 | 0.748039 | 3 | 0 | 3 |
| DBF4B | LRWD1 | 0.73852 | 3 | 0 | 3 |
| DBF4B | COL27A1 | 0.737931 | 4 | 0 | 4 |
| DBF4B | NAT14 | 0.73096 | 4 | 0 | 4 |
| DBF4B | TTYH3 | 0.725095 | 3 | 0 | 3 |
| DBF4B | KIF4A | 0.724974 | 5 | 0 | 5 |
| DBF4B | SMPD4 | 0.721882 | 3 | 0 | 3 |
| DBF4B | SLC39A4 | 0.716689 | 3 | 0 | 3 |
| DBF4B | SPP1 | 0.715874 | 3 | 0 | 3 |
| DBF4B | DNMT3B | 0.715732 | 5 | 0 | 4 |
| DBF4B | COLGALT1 | 0.715473 | 3 | 0 | 3 |
| DBF4B | PMEPA1 | 0.707436 | 4 | 0 | 4 |
| DBF4B | POLD1 | 0.700003 | 4 | 0 | 4 |
| DBF4B | TAS2R30 | 0.695304 | 3 | 0 | 3 |
| DBF4B | MRGBP | 0.690516 | 4 | 0 | 4 |
| DBF4B | CHRNB4 | 0.689771 | 3 | 0 | 3 |
| DBF4B | GPRIN1 | 0.687901 | 6 | 0 | 5 |
| DBF4B | C1QTNF6 | 0.686448 | 5 | 0 | 4 |
For details and further investigation, click here
