| Full name: F-box protein 34 | Alias Symbol: FLJ20725|Fbx34 | ||
| Type: protein-coding gene | Cytoband: 14q22.3 | ||
| Entrez ID: 55030 | HGNC ID: HGNC:20201 | Ensembl Gene: ENSG00000178974 | OMIM ID: 609104 |
| Drug and gene relationship at DGIdb | |||
Expression of FBXO34:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FBXO34 | 55030 | 218539_at | -0.4803 | 0.3224 | |
| GSE20347 | FBXO34 | 55030 | 218539_at | -0.8366 | 0.0000 | |
| GSE23400 | FBXO34 | 55030 | 218539_at | -1.0048 | 0.0000 | |
| GSE26886 | FBXO34 | 55030 | 218539_at | -1.5767 | 0.0000 | |
| GSE29001 | FBXO34 | 55030 | 218539_at | -1.0521 | 0.0004 | |
| GSE38129 | FBXO34 | 55030 | 218539_at | -0.6111 | 0.0035 | |
| GSE45670 | FBXO34 | 55030 | 218539_at | -0.3056 | 0.2341 | |
| GSE53622 | FBXO34 | 55030 | 124284 | -1.0908 | 0.0000 | |
| GSE53624 | FBXO34 | 55030 | 124284 | -1.5587 | 0.0000 | |
| GSE63941 | FBXO34 | 55030 | 218539_at | 1.0862 | 0.0081 | |
| GSE77861 | FBXO34 | 55030 | 218539_at | -1.1097 | 0.0038 | |
| GSE97050 | FBXO34 | 55030 | A_33_P3237225 | -0.2537 | 0.4238 | |
| SRP007169 | FBXO34 | 55030 | RNAseq | -2.6142 | 0.0000 | |
| SRP008496 | FBXO34 | 55030 | RNAseq | -2.6755 | 0.0000 | |
| SRP064894 | FBXO34 | 55030 | RNAseq | -1.7007 | 0.0000 | |
| SRP133303 | FBXO34 | 55030 | RNAseq | -1.1889 | 0.0000 | |
| SRP159526 | FBXO34 | 55030 | RNAseq | -1.3479 | 0.0000 | |
| SRP193095 | FBXO34 | 55030 | RNAseq | -1.6636 | 0.0000 | |
| SRP219564 | FBXO34 | 55030 | RNAseq | -1.0871 | 0.0665 | |
| TCGA | FBXO34 | 55030 | RNAseq | 0.0185 | 0.7479 |
Upregulated datasets: 1; Downregulated datasets: 12.
Survival by FBXO34 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FBXO34:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FBXO34 | 55030 | 8 | 3 | 19 | |
| GSE20123 | FBXO34 | 55030 | 8 | 3 | 19 | |
| GSE43470 | FBXO34 | 55030 | 9 | 1 | 33 | |
| GSE46452 | FBXO34 | 55030 | 16 | 3 | 40 | |
| GSE47630 | FBXO34 | 55030 | 11 | 10 | 19 | |
| GSE54993 | FBXO34 | 55030 | 3 | 8 | 59 | |
| GSE54994 | FBXO34 | 55030 | 19 | 4 | 30 | |
| GSE60625 | FBXO34 | 55030 | 0 | 2 | 9 | |
| GSE74703 | FBXO34 | 55030 | 8 | 1 | 27 | |
| GSE74704 | FBXO34 | 55030 | 3 | 2 | 15 | |
| TCGA | FBXO34 | 55030 | 32 | 14 | 50 |
Total number of gains: 117; Total number of losses: 51; Total Number of normals: 320.
Somatic mutations of FBXO34:
Generating mutation plots.
Highly correlated genes for FBXO34:
Showing top 20/789 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FBXO34 | FAM163B | 0.870787 | 3 | 0 | 3 |
| FBXO34 | FUT3 | 0.833142 | 10 | 0 | 10 |
| FBXO34 | GYS2 | 0.826016 | 10 | 0 | 10 |
| FBXO34 | FAM214A | 0.820352 | 6 | 0 | 6 |
| FBXO34 | MUC22 | 0.819797 | 3 | 0 | 3 |
| FBXO34 | NCCRP1 | 0.81752 | 3 | 0 | 3 |
| FBXO34 | KRT78 | 0.815949 | 6 | 0 | 6 |
| FBXO34 | ANXA9 | 0.810996 | 10 | 0 | 10 |
| FBXO34 | TTC9 | 0.810651 | 11 | 0 | 10 |
| FBXO34 | SH3BGRL2 | 0.810112 | 6 | 0 | 6 |
| FBXO34 | ESPL1 | 0.806773 | 11 | 0 | 11 |
| FBXO34 | HOPX | 0.801556 | 9 | 0 | 9 |
| FBXO34 | TMPRSS11E | 0.800857 | 10 | 0 | 10 |
| FBXO34 | NT5C2 | 0.796579 | 10 | 0 | 10 |
| FBXO34 | FAM3B | 0.796133 | 6 | 0 | 6 |
| FBXO34 | YOD1 | 0.795824 | 10 | 0 | 9 |
| FBXO34 | KRTAP20-1 | 0.795743 | 3 | 0 | 3 |
| FBXO34 | ACPP | 0.795234 | 11 | 0 | 11 |
| FBXO34 | CRISP3 | 0.79486 | 10 | 0 | 10 |
| FBXO34 | OTOP3 | 0.794226 | 3 | 0 | 3 |
For details and further investigation, click here
