| Full name: sorting nexin 31 | Alias Symbol: MGC39715 | ||
| Type: protein-coding gene | Cytoband: 8q22.3 | ||
| Entrez ID: 169166 | HGNC ID: HGNC:28605 | Ensembl Gene: ENSG00000174226 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of SNX31:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SNX31 | 169166 | 241987_x_at | -0.8540 | 0.7296 | |
| GSE26886 | SNX31 | 169166 | 241987_x_at | -2.0036 | 0.0002 | |
| GSE45670 | SNX31 | 169166 | 241987_x_at | -0.5916 | 0.4310 | |
| GSE53622 | SNX31 | 169166 | 71433 | -2.3447 | 0.0000 | |
| GSE53624 | SNX31 | 169166 | 71433 | -2.9446 | 0.0000 | |
| GSE63941 | SNX31 | 169166 | 241987_x_at | 0.2433 | 0.7806 | |
| GSE77861 | SNX31 | 169166 | 241987_x_at | -0.8063 | 0.0628 | |
| SRP007169 | SNX31 | 169166 | RNAseq | -4.1962 | 0.0000 | |
| SRP008496 | SNX31 | 169166 | RNAseq | -3.9717 | 0.0000 | |
| SRP064894 | SNX31 | 169166 | RNAseq | -1.7620 | 0.0006 | |
| SRP133303 | SNX31 | 169166 | RNAseq | -0.8886 | 0.3505 | |
| SRP159526 | SNX31 | 169166 | RNAseq | -2.3379 | 0.0113 | |
| SRP219564 | SNX31 | 169166 | RNAseq | -2.7368 | 0.0201 | |
| TCGA | SNX31 | 169166 | RNAseq | 0.8759 | 0.1213 |
Upregulated datasets: 0; Downregulated datasets: 8.
Survival by SNX31 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SNX31:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SNX31 | 169166 | 17 | 0 | 13 | |
| GSE20123 | SNX31 | 169166 | 17 | 0 | 13 | |
| GSE43470 | SNX31 | 169166 | 22 | 0 | 21 | |
| GSE46452 | SNX31 | 169166 | 24 | 0 | 35 | |
| GSE47630 | SNX31 | 169166 | 24 | 0 | 16 | |
| GSE54993 | SNX31 | 169166 | 0 | 20 | 50 | |
| GSE54994 | SNX31 | 169166 | 38 | 1 | 14 | |
| GSE60625 | SNX31 | 169166 | 0 | 4 | 7 | |
| GSE74703 | SNX31 | 169166 | 19 | 0 | 17 | |
| GSE74704 | SNX31 | 169166 | 12 | 0 | 8 | |
| TCGA | SNX31 | 169166 | 59 | 1 | 36 |
Total number of gains: 232; Total number of losses: 26; Total Number of normals: 230.
Somatic mutations of SNX31:
Generating mutation plots.
Highly correlated genes for SNX31:
Showing top 20/801 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SNX31 | IKZF2 | 0.729622 | 6 | 0 | 6 |
| SNX31 | BCAS1 | 0.726688 | 6 | 0 | 5 |
| SNX31 | SP1 | 0.726609 | 5 | 0 | 5 |
| SNX31 | EXPH5 | 0.716319 | 6 | 0 | 6 |
| SNX31 | JADE3 | 0.71436 | 3 | 0 | 3 |
| SNX31 | CEACAM7 | 0.710693 | 5 | 0 | 5 |
| SNX31 | FAM3B | 0.708194 | 7 | 0 | 6 |
| SNX31 | SLC16A6 | 0.708043 | 5 | 0 | 5 |
| SNX31 | TMPRSS11B | 0.705743 | 5 | 0 | 5 |
| SNX31 | EHD3 | 0.702377 | 5 | 0 | 5 |
| SNX31 | SPINK5 | 0.697929 | 5 | 0 | 5 |
| SNX31 | CRNN | 0.69505 | 5 | 0 | 5 |
| SNX31 | SLC37A1 | 0.692769 | 6 | 0 | 6 |
| SNX31 | CRISP3 | 0.690221 | 5 | 0 | 5 |
| SNX31 | UBN2 | 0.689738 | 3 | 0 | 3 |
| SNX31 | CXCR2 | 0.688042 | 5 | 0 | 5 |
| SNX31 | CPNE3 | 0.687735 | 6 | 0 | 6 |
| SNX31 | ZNF675 | 0.685464 | 4 | 0 | 4 |
| SNX31 | SUDS3 | 0.681931 | 3 | 0 | 3 |
| SNX31 | RHCG | 0.681626 | 5 | 0 | 5 |
For details and further investigation, click here
