| Full name: transmembrane protein 217 | Alias Symbol: dJ355M6.2 | ||
| Type: protein-coding gene | Cytoband: 6p21.2 | ||
| Entrez ID: 221468 | HGNC ID: HGNC:21238 | Ensembl Gene: ENSG00000172738 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of TMEM217:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TMEM217 | 221468 | 237016_at | -0.1080 | 0.6504 | |
| GSE26886 | TMEM217 | 221468 | 237016_at | -0.7238 | 0.0002 | |
| GSE45670 | TMEM217 | 221468 | 237016_at | -0.1835 | 0.1903 | |
| GSE53622 | TMEM217 | 221468 | 77592 | -0.0881 | 0.3133 | |
| GSE53624 | TMEM217 | 221468 | 77592 | -0.4846 | 0.0000 | |
| GSE63941 | TMEM217 | 221468 | 237016_at | -0.7580 | 0.0005 | |
| GSE77861 | TMEM217 | 221468 | 237016_at | -0.2671 | 0.0465 | |
| GSE97050 | TMEM217 | 221468 | A_23_P334870 | 0.1215 | 0.5556 | |
| SRP007169 | TMEM217 | 221468 | RNAseq | -2.9213 | 0.0000 | |
| SRP064894 | TMEM217 | 221468 | RNAseq | -1.5864 | 0.0000 | |
| SRP133303 | TMEM217 | 221468 | RNAseq | -1.2917 | 0.0000 | |
| SRP159526 | TMEM217 | 221468 | RNAseq | -2.5965 | 0.0000 | |
| SRP219564 | TMEM217 | 221468 | RNAseq | -1.4968 | 0.0105 | |
| TCGA | TMEM217 | 221468 | RNAseq | -0.2043 | 0.3591 |
Upregulated datasets: 0; Downregulated datasets: 5.
Survival by TMEM217 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TMEM217:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TMEM217 | 221468 | 6 | 0 | 24 | |
| GSE20123 | TMEM217 | 221468 | 6 | 0 | 24 | |
| GSE43470 | TMEM217 | 221468 | 5 | 1 | 37 | |
| GSE46452 | TMEM217 | 221468 | 2 | 9 | 48 | |
| GSE47630 | TMEM217 | 221468 | 8 | 4 | 28 | |
| GSE54993 | TMEM217 | 221468 | 3 | 1 | 66 | |
| GSE54994 | TMEM217 | 221468 | 10 | 5 | 38 | |
| GSE60625 | TMEM217 | 221468 | 1 | 0 | 10 | |
| GSE74703 | TMEM217 | 221468 | 5 | 0 | 31 | |
| GSE74704 | TMEM217 | 221468 | 3 | 0 | 17 | |
| TCGA | TMEM217 | 221468 | 16 | 14 | 66 |
Total number of gains: 65; Total number of losses: 34; Total Number of normals: 389.
Somatic mutations of TMEM217:
Generating mutation plots.
Highly correlated genes for TMEM217:
Showing top 20/201 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TMEM217 | PRRG1 | 0.759288 | 3 | 0 | 3 |
| TMEM217 | PPM1F | 0.758049 | 3 | 0 | 3 |
| TMEM217 | ANKRD33 | 0.751148 | 3 | 0 | 3 |
| TMEM217 | SEC14L3 | 0.738969 | 4 | 0 | 4 |
| TMEM217 | UBN2 | 0.736215 | 3 | 0 | 3 |
| TMEM217 | FHIT | 0.733481 | 4 | 0 | 4 |
| TMEM217 | VILL | 0.72513 | 4 | 0 | 4 |
| TMEM217 | MAPKAPK3 | 0.719936 | 4 | 0 | 4 |
| TMEM217 | SUN2 | 0.71214 | 3 | 0 | 3 |
| TMEM217 | TBKBP1 | 0.706095 | 5 | 0 | 5 |
| TMEM217 | RAB17 | 0.70152 | 3 | 0 | 3 |
| TMEM217 | GRIPAP1 | 0.696516 | 3 | 0 | 3 |
| TMEM217 | SNAP91 | 0.694921 | 3 | 0 | 3 |
| TMEM217 | SLC48A1 | 0.686687 | 5 | 0 | 4 |
| TMEM217 | BUD13 | 0.681315 | 5 | 0 | 5 |
| TMEM217 | GSKIP | 0.676483 | 3 | 0 | 3 |
| TMEM217 | B3GNT8 | 0.673709 | 5 | 0 | 4 |
| TMEM217 | NICN1 | 0.671897 | 4 | 0 | 3 |
| TMEM217 | NLRP6 | 0.671336 | 3 | 0 | 3 |
| TMEM217 | ERBB2 | 0.666321 | 5 | 0 | 5 |
For details and further investigation, click here
