| Full name: VAMP associated protein B and C | Alias Symbol: VAP-B|VAP-C|ALS8 | ||
| Type: protein-coding gene | Cytoband: 20q13.32 | ||
| Entrez ID: 9217 | HGNC ID: HGNC:12649 | Ensembl Gene: ENSG00000124164 | OMIM ID: 605704 |
| Drug and gene relationship at DGIdb | |||
Expression of VAPB:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | VAPB | 9217 | 202550_s_at | 1.1026 | 0.0523 | |
| GSE20347 | VAPB | 9217 | 202550_s_at | 0.3394 | 0.0264 | |
| GSE23400 | VAPB | 9217 | 202550_s_at | 0.4493 | 0.0000 | |
| GSE26886 | VAPB | 9217 | 202550_s_at | -0.3486 | 0.0634 | |
| GSE29001 | VAPB | 9217 | 202550_s_at | 0.5381 | 0.0256 | |
| GSE38129 | VAPB | 9217 | 202550_s_at | 0.2856 | 0.0137 | |
| GSE45670 | VAPB | 9217 | 202550_s_at | 0.3092 | 0.0274 | |
| GSE53622 | VAPB | 9217 | 24257 | -0.0253 | 0.8309 | |
| GSE53624 | VAPB | 9217 | 96054 | 0.1285 | 0.1691 | |
| GSE63941 | VAPB | 9217 | 202550_s_at | 0.3463 | 0.3842 | |
| GSE77861 | VAPB | 9217 | 202550_s_at | 0.1229 | 0.5192 | |
| GSE97050 | VAPB | 9217 | A_33_P3365586 | -0.2233 | 0.6479 | |
| SRP007169 | VAPB | 9217 | RNAseq | 0.1616 | 0.6347 | |
| SRP008496 | VAPB | 9217 | RNAseq | 0.0221 | 0.9063 | |
| SRP064894 | VAPB | 9217 | RNAseq | 0.3636 | 0.0293 | |
| SRP133303 | VAPB | 9217 | RNAseq | 0.2662 | 0.0160 | |
| SRP159526 | VAPB | 9217 | RNAseq | 0.2143 | 0.3991 | |
| SRP193095 | VAPB | 9217 | RNAseq | 0.2184 | 0.0187 | |
| SRP219564 | VAPB | 9217 | RNAseq | 0.2896 | 0.1826 | |
| TCGA | VAPB | 9217 | RNAseq | -0.0343 | 0.4575 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by VAPB expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of VAPB:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | VAPB | 9217 | 14 | 2 | 14 | |
| GSE20123 | VAPB | 9217 | 14 | 2 | 14 | |
| GSE43470 | VAPB | 9217 | 13 | 0 | 30 | |
| GSE46452 | VAPB | 9217 | 29 | 0 | 30 | |
| GSE47630 | VAPB | 9217 | 24 | 1 | 15 | |
| GSE54993 | VAPB | 9217 | 0 | 17 | 53 | |
| GSE54994 | VAPB | 9217 | 29 | 0 | 24 | |
| GSE60625 | VAPB | 9217 | 0 | 0 | 11 | |
| GSE74703 | VAPB | 9217 | 11 | 0 | 25 | |
| GSE74704 | VAPB | 9217 | 11 | 0 | 9 | |
| TCGA | VAPB | 9217 | 43 | 4 | 49 |
Total number of gains: 188; Total number of losses: 26; Total Number of normals: 274.
Somatic mutations of VAPB:
Generating mutation plots.
Highly correlated genes for VAPB:
Showing top 20/632 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| VAPB | CMTM4 | 0.780242 | 3 | 0 | 3 |
| VAPB | KBTBD6 | 0.769604 | 3 | 0 | 3 |
| VAPB | IRF1 | 0.766404 | 3 | 0 | 3 |
| VAPB | ARHGEF11 | 0.755149 | 3 | 0 | 3 |
| VAPB | C12orf45 | 0.754723 | 3 | 0 | 3 |
| VAPB | KLHL36 | 0.736709 | 4 | 0 | 4 |
| VAPB | EBAG9 | 0.735383 | 3 | 0 | 3 |
| VAPB | IFFO2 | 0.731315 | 3 | 0 | 3 |
| VAPB | SWT1 | 0.727448 | 3 | 0 | 3 |
| VAPB | DDX55 | 0.726496 | 3 | 0 | 3 |
| VAPB | STAU1 | 0.719159 | 9 | 0 | 9 |
| VAPB | CD83 | 0.708873 | 3 | 0 | 3 |
| VAPB | PET117 | 0.705027 | 4 | 0 | 4 |
| VAPB | PSMA7 | 0.704672 | 10 | 0 | 8 |
| VAPB | HSDL1 | 0.703622 | 3 | 0 | 3 |
| VAPB | SLC25A36 | 0.701272 | 3 | 0 | 3 |
| VAPB | MRPL55 | 0.699949 | 3 | 0 | 3 |
| VAPB | GOLGA3 | 0.699681 | 3 | 0 | 3 |
| VAPB | HMGXB4 | 0.696066 | 3 | 0 | 3 |
| VAPB | SLC7A6OS | 0.694734 | 4 | 0 | 3 |
For details and further investigation, click here
