HMGXB4

 

Full name: HMG-box containing 4 Alias Symbol: THC211630
Type: protein-coding gene Cytoband: 22q12.3
Entrez ID: 10042 HGNC ID: HGNC:5003 Ensembl Gene: ENSG00000100281 OMIM ID: 604702
Drug and gene relationship at DGIdb

 

Expression of HMGXB4:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 HMGXB4 10042 212596_s_at 0.6204 0.1004
GSE20347 HMGXB4 10042 212596_s_at 0.4406 0.0004
GSE23400 HMGXB4 10042 212597_s_at 0.4567 0.0000
GSE26886 HMGXB4 10042 212597_s_at 0.5419 0.0050
GSE29001 HMGXB4 10042 212596_s_at 0.3630 0.3595
GSE38129 HMGXB4 10042 212596_s_at 0.3829 0.0009
GSE45670 HMGXB4 10042 212596_s_at 0.2844 0.0689
GSE53622 HMGXB4 10042 3691 0.2671 0.0000
GSE53624 HMGXB4 10042 17820 0.3258 0.0000
GSE63941 HMGXB4 10042 212596_s_at 0.8613 0.0301
GSE77861 HMGXB4 10042 212597_s_at 0.5178 0.0063
GSE97050 HMGXB4 10042 A_23_P431981 0.0938 0.8018
SRP007169 HMGXB4 10042 RNAseq 0.4602 0.1716
SRP008496 HMGXB4 10042 RNAseq 0.2525 0.2524
SRP064894 HMGXB4 10042 RNAseq 0.2100 0.2641
SRP133303 HMGXB4 10042 RNAseq 0.3067 0.0593
SRP159526 HMGXB4 10042 RNAseq 0.4502 0.0009
SRP193095 HMGXB4 10042 RNAseq 0.1159 0.2534
SRP219564 HMGXB4 10042 RNAseq 0.1963 0.5768
TCGA HMGXB4 10042 RNAseq 0.2208 0.0000

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by HMGXB4 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of HMGXB4:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 HMGXB4 10042 4 6 20
GSE20123 HMGXB4 10042 4 5 21
GSE43470 HMGXB4 10042 4 6 33
GSE46452 HMGXB4 10042 31 1 27
GSE47630 HMGXB4 10042 8 5 27
GSE54993 HMGXB4 10042 3 6 61
GSE54994 HMGXB4 10042 9 9 35
GSE60625 HMGXB4 10042 5 0 6
GSE74703 HMGXB4 10042 4 5 27
GSE74704 HMGXB4 10042 1 2 17
TCGA HMGXB4 10042 28 15 53

Total number of gains: 101; Total number of losses: 60; Total Number of normals: 327.  

 

Somatic mutations of HMGXB4:

 

Generating mutation plots.

 

Highly correlated genes for HMGXB4:

 

Showing top 20/1176 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
HMGXB4FAM32A0.767751303
HMGXB4EIF5B0.762126505
HMGXB4ZNF518B0.744355403
HMGXB4DYRK20.743416303
HMGXB4CBFA2T20.731923403
HMGXB4SFSWAP0.731177404
HMGXB4NACC10.72928404
HMGXB4SPIRE20.728866303
HMGXB4CMTM40.722797404
HMGXB4FIP1L10.718594605
HMGXB4PPP1R9B0.716611303
HMGXB4PPP1R16A0.712451403
HMGXB4U2SURP0.708269909
HMGXB4ZDHHC70.708035303
HMGXB4KRTCAP20.706937404
HMGXB4C1QA0.704801303
HMGXB4MOB3C0.704449303
HMGXB4MORC20.70198909
HMGXB4WDR810.701288404
HMGXB4EXOC80.69923403

For details and further investigation, click here