PSMA7

 

Full name: proteasome subunit alpha 7 Alias Symbol: XAPC7|C6|HSPC|RC6-1
Type: protein-coding gene Cytoband: 20q13.33
Entrez ID: 5688 HGNC ID: HGNC:9536 Ensembl Gene: ENSG00000101182 OMIM ID: 606607
Drug and gene relationship at DGIdb

 

Expression of PSMA7:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 PSMA7 5688 201114_x_at 0.8125 0.0407
GSE20347 PSMA7 5688 201114_x_at 0.5842 0.0002
GSE23400 PSMA7 5688 201114_x_at 0.6791 0.0000
GSE26886 PSMA7 5688 201114_x_at 0.1840 0.3067
GSE29001 PSMA7 5688 201114_x_at 0.6509 0.0725
GSE38129 PSMA7 5688 201114_x_at 0.6757 0.0000
GSE45670 PSMA7 5688 201114_x_at 0.5183 0.0005
GSE53622 PSMA7 5688 114682 0.5046 0.0000
GSE53624 PSMA7 5688 114682 0.9215 0.0000
GSE63941 PSMA7 5688 201114_x_at 0.2648 0.4825
GSE77861 PSMA7 5688 201114_x_at 0.5876 0.0114
GSE97050 PSMA7 5688 A_23_P91468 0.4392 0.2272
SRP007169 PSMA7 5688 RNAseq -0.4043 0.1886
SRP008496 PSMA7 5688 RNAseq -0.0789 0.6773
SRP064894 PSMA7 5688 RNAseq 0.8001 0.0018
SRP133303 PSMA7 5688 RNAseq 0.7378 0.0000
SRP159526 PSMA7 5688 RNAseq 0.5232 0.0002
SRP193095 PSMA7 5688 RNAseq 0.2762 0.0356
SRP219564 PSMA7 5688 RNAseq 0.5609 0.1170
TCGA PSMA7 5688 RNAseq 0.2469 0.0000

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by PSMA7 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of PSMA7:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 PSMA7 5688 13 2 15
GSE20123 PSMA7 5688 14 2 14
GSE43470 PSMA7 5688 11 1 31
GSE46452 PSMA7 5688 35 0 24
GSE47630 PSMA7 5688 25 1 14
GSE54993 PSMA7 5688 0 17 53
GSE54994 PSMA7 5688 29 0 24
GSE60625 PSMA7 5688 0 0 11
GSE74703 PSMA7 5688 10 0 26
GSE74704 PSMA7 5688 11 0 9
TCGA PSMA7 5688 43 4 49

Total number of gains: 191; Total number of losses: 27; Total Number of normals: 270.  


 

Somatic mutations of PSMA7:

 

Generating mutation plots.

 

Highly correlated genes for PSMA7:

 

Showing top 20/1749 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
PSMA7MRGBP0.7615761009
PSMA7NME10.75536909
PSMA7RUVBL10.752622909
PSMA7ZNF6700.751025303
PSMA7CKAP2L0.739976504
PSMA7SLC7A6OS0.737261404
PSMA7PNPT10.733964505
PSMA7NELFCD0.7320911009
PSMA7C20orf270.730905808
PSMA7AURKA0.7301611009
PSMA7GEMIN60.72840910010
PSMA7HAS30.726184404
PSMA7ELOF10.720575303
PSMA7EIF3B0.719026909
PSMA7UBE2C0.71758911010
PSMA7ADRM10.71485211010
PSMA7YTHDF10.71459412010
PSMA7CDCA20.713591504
PSMA7PES10.712745909
PSMA7TOMM340.71062808

For details and further investigation, click here