| Full name: intermediate filament family orphan 2 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 1p36.13 | ||
| Entrez ID: 126917 | HGNC ID: HGNC:27006 | Ensembl Gene: ENSG00000169991 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of IFFO2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | IFFO2 | 126917 | 225615_at | 0.7316 | 0.1193 | |
| GSE26886 | IFFO2 | 126917 | 225615_at | -0.3057 | 0.4623 | |
| GSE45670 | IFFO2 | 126917 | 225615_at | 0.4282 | 0.2489 | |
| GSE53622 | IFFO2 | 126917 | 71553 | -0.5253 | 0.0065 | |
| GSE53624 | IFFO2 | 126917 | 71553 | -0.5168 | 0.0000 | |
| GSE63941 | IFFO2 | 126917 | 225615_at | 1.0957 | 0.0849 | |
| GSE77861 | IFFO2 | 126917 | 225615_at | 0.2985 | 0.3465 | |
| GSE97050 | IFFO2 | 126917 | A_23_P418031 | -0.0321 | 0.9326 | |
| SRP007169 | IFFO2 | 126917 | RNAseq | -0.3419 | 0.3471 | |
| SRP008496 | IFFO2 | 126917 | RNAseq | -0.5890 | 0.0394 | |
| SRP064894 | IFFO2 | 126917 | RNAseq | -1.0453 | 0.0023 | |
| SRP133303 | IFFO2 | 126917 | RNAseq | -0.5815 | 0.1820 | |
| SRP159526 | IFFO2 | 126917 | RNAseq | -0.7428 | 0.1643 | |
| SRP193095 | IFFO2 | 126917 | RNAseq | 0.7351 | 0.0279 | |
| SRP219564 | IFFO2 | 126917 | RNAseq | -1.5373 | 0.0212 | |
| TCGA | IFFO2 | 126917 | RNAseq | 0.4292 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by IFFO2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of IFFO2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | IFFO2 | 126917 | 0 | 5 | 25 | |
| GSE20123 | IFFO2 | 126917 | 0 | 4 | 26 | |
| GSE43470 | IFFO2 | 126917 | 0 | 8 | 35 | |
| GSE46452 | IFFO2 | 126917 | 5 | 1 | 53 | |
| GSE47630 | IFFO2 | 126917 | 8 | 3 | 29 | |
| GSE54993 | IFFO2 | 126917 | 3 | 1 | 66 | |
| GSE54994 | IFFO2 | 126917 | 11 | 4 | 38 | |
| GSE60625 | IFFO2 | 126917 | 0 | 0 | 11 | |
| GSE74703 | IFFO2 | 126917 | 0 | 5 | 31 | |
| GSE74704 | IFFO2 | 126917 | 0 | 0 | 20 | |
| TCGA | IFFO2 | 126917 | 10 | 22 | 64 |
Total number of gains: 37; Total number of losses: 53; Total Number of normals: 398.
Somatic mutations of IFFO2:
Generating mutation plots.
Highly correlated genes for IFFO2:
Showing top 20/264 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| IFFO2 | ARHGEF11 | 0.787148 | 3 | 0 | 3 |
| IFFO2 | LETM2 | 0.780566 | 3 | 0 | 3 |
| IFFO2 | FAM86C1 | 0.780537 | 3 | 0 | 3 |
| IFFO2 | CLSPN | 0.778612 | 3 | 0 | 3 |
| IFFO2 | RRAS2 | 0.760238 | 3 | 0 | 3 |
| IFFO2 | SOCS7 | 0.755192 | 3 | 0 | 3 |
| IFFO2 | MAP4K2 | 0.754558 | 3 | 0 | 3 |
| IFFO2 | C1orf226 | 0.751291 | 3 | 0 | 3 |
| IFFO2 | MAP4K4 | 0.736481 | 3 | 0 | 3 |
| IFFO2 | FAM89B | 0.73491 | 3 | 0 | 3 |
| IFFO2 | VAPB | 0.731315 | 3 | 0 | 3 |
| IFFO2 | TRAF3IP1 | 0.72918 | 3 | 0 | 3 |
| IFFO2 | CBL | 0.726395 | 4 | 0 | 3 |
| IFFO2 | S1PR5 | 0.725638 | 3 | 0 | 3 |
| IFFO2 | BTBD6 | 0.717013 | 3 | 0 | 3 |
| IFFO2 | CNOT7 | 0.703012 | 3 | 0 | 3 |
| IFFO2 | ASAP2 | 0.698422 | 3 | 0 | 3 |
| IFFO2 | MOB3C | 0.697849 | 4 | 0 | 4 |
| IFFO2 | INO80E | 0.697463 | 3 | 0 | 3 |
| IFFO2 | SF3B2 | 0.696524 | 3 | 0 | 3 |
For details and further investigation, click here
