| Full name: staufen double-stranded RNA binding protein 1 | Alias Symbol: PPP1R150 | ||
| Type: protein-coding gene | Cytoband: 20q13.13 | ||
| Entrez ID: 6780 | HGNC ID: HGNC:11370 | Ensembl Gene: ENSG00000124214 | OMIM ID: 601716 |
| Drug and gene relationship at DGIdb | |||
Expression of STAU1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | STAU1 | 6780 | 207320_x_at | 0.5668 | 0.1180 | |
| GSE20347 | STAU1 | 6780 | 213037_x_at | 0.3090 | 0.0078 | |
| GSE23400 | STAU1 | 6780 | 207320_x_at | 0.2811 | 0.0000 | |
| GSE26886 | STAU1 | 6780 | 213037_x_at | -0.0636 | 0.7305 | |
| GSE29001 | STAU1 | 6780 | 213037_x_at | 0.4006 | 0.0035 | |
| GSE38129 | STAU1 | 6780 | 213037_x_at | 0.2762 | 0.0044 | |
| GSE45670 | STAU1 | 6780 | 213037_x_at | 0.1838 | 0.0915 | |
| GSE53622 | STAU1 | 6780 | 63209 | 0.3360 | 0.0000 | |
| GSE53624 | STAU1 | 6780 | 97997 | 0.4684 | 0.0000 | |
| GSE63941 | STAU1 | 6780 | 207320_x_at | 0.1120 | 0.7578 | |
| GSE77861 | STAU1 | 6780 | 207320_x_at | 0.2651 | 0.1616 | |
| GSE97050 | STAU1 | 6780 | A_23_P57059 | 0.2250 | 0.5321 | |
| SRP007169 | STAU1 | 6780 | RNAseq | -0.2383 | 0.3985 | |
| SRP008496 | STAU1 | 6780 | RNAseq | -0.1092 | 0.5241 | |
| SRP064894 | STAU1 | 6780 | RNAseq | 0.1505 | 0.1780 | |
| SRP133303 | STAU1 | 6780 | RNAseq | 0.4562 | 0.0000 | |
| SRP159526 | STAU1 | 6780 | RNAseq | 0.2554 | 0.0900 | |
| SRP193095 | STAU1 | 6780 | RNAseq | 0.0996 | 0.3051 | |
| SRP219564 | STAU1 | 6780 | RNAseq | 0.0761 | 0.7828 | |
| TCGA | STAU1 | 6780 | RNAseq | 0.0068 | 0.8673 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by STAU1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of STAU1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | STAU1 | 6780 | 16 | 2 | 12 | |
| GSE20123 | STAU1 | 6780 | 16 | 2 | 12 | |
| GSE43470 | STAU1 | 6780 | 12 | 0 | 31 | |
| GSE46452 | STAU1 | 6780 | 29 | 0 | 30 | |
| GSE47630 | STAU1 | 6780 | 24 | 1 | 15 | |
| GSE54993 | STAU1 | 6780 | 0 | 18 | 52 | |
| GSE54994 | STAU1 | 6780 | 26 | 1 | 26 | |
| GSE60625 | STAU1 | 6780 | 0 | 0 | 11 | |
| GSE74703 | STAU1 | 6780 | 10 | 0 | 26 | |
| GSE74704 | STAU1 | 6780 | 12 | 0 | 8 | |
| TCGA | STAU1 | 6780 | 46 | 3 | 47 |
Total number of gains: 191; Total number of losses: 27; Total Number of normals: 270.
Somatic mutations of STAU1:
Generating mutation plots.
Highly correlated genes for STAU1:
Showing top 20/893 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| STAU1 | SLC7A6OS | 0.812541 | 3 | 0 | 3 |
| STAU1 | SPNS1 | 0.811442 | 3 | 0 | 3 |
| STAU1 | LRRC58 | 0.802005 | 3 | 0 | 3 |
| STAU1 | TMEM186 | 0.770656 | 3 | 0 | 3 |
| STAU1 | NUP54 | 0.763278 | 3 | 0 | 3 |
| STAU1 | NSD1 | 0.749112 | 3 | 0 | 3 |
| STAU1 | TP53RK | 0.742768 | 4 | 0 | 3 |
| STAU1 | SMAD1 | 0.729954 | 4 | 0 | 4 |
| STAU1 | TM2D2 | 0.723798 | 3 | 0 | 3 |
| STAU1 | VAPB | 0.719159 | 9 | 0 | 9 |
| STAU1 | ORAI3 | 0.718385 | 3 | 0 | 3 |
| STAU1 | TRIM59 | 0.71604 | 3 | 0 | 3 |
| STAU1 | CHML | 0.715075 | 4 | 0 | 3 |
| STAU1 | KIF3B | 0.714261 | 8 | 0 | 8 |
| STAU1 | PTPRG | 0.709834 | 4 | 0 | 4 |
| STAU1 | ALG1 | 0.709349 | 4 | 0 | 4 |
| STAU1 | PAK1IP1 | 0.708643 | 3 | 0 | 3 |
| STAU1 | NUP133 | 0.706535 | 4 | 0 | 3 |
| STAU1 | WDR4 | 0.703798 | 3 | 0 | 3 |
| STAU1 | MMP15 | 0.702886 | 5 | 0 | 4 |
For details and further investigation, click here
