| Full name: mediator complex subunit 24 | Alias Symbol: TRAP100|KIAA0130|DRIP100|CRSP100|MED5 | ||
| Type: protein-coding gene | Cytoband: 17q21.1 | ||
| Entrez ID: 9862 | HGNC ID: HGNC:22963 | Ensembl Gene: ENSG00000008838 | OMIM ID: 607000 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of MED24:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MED24 | 9862 | 215337_at | 0.1364 | 0.5815 | |
| GSE20347 | MED24 | 9862 | 215337_at | 0.1011 | 0.3080 | |
| GSE23400 | MED24 | 9862 | 215337_at | -0.0948 | 0.0021 | |
| GSE26886 | MED24 | 9862 | 215337_at | -0.0541 | 0.7147 | |
| GSE29001 | MED24 | 9862 | 215337_at | -0.0734 | 0.6449 | |
| GSE38129 | MED24 | 9862 | 215337_at | 0.0030 | 0.9796 | |
| GSE45670 | MED24 | 9862 | 215337_at | 0.1306 | 0.2200 | |
| GSE53622 | MED24 | 9862 | 70070 | 0.0941 | 0.1343 | |
| GSE53624 | MED24 | 9862 | 70070 | 0.2752 | 0.0000 | |
| GSE63941 | MED24 | 9862 | 215337_at | 0.2159 | 0.2738 | |
| GSE77861 | MED24 | 9862 | 215337_at | -0.0485 | 0.6295 | |
| GSE97050 | MED24 | 9862 | A_23_P124760 | 0.7518 | 0.0737 | |
| SRP007169 | MED24 | 9862 | RNAseq | 1.2007 | 0.0335 | |
| SRP008496 | MED24 | 9862 | RNAseq | 0.8760 | 0.0385 | |
| SRP064894 | MED24 | 9862 | RNAseq | 0.1724 | 0.2175 | |
| SRP133303 | MED24 | 9862 | RNAseq | 0.1003 | 0.5864 | |
| SRP159526 | MED24 | 9862 | RNAseq | 0.0236 | 0.9290 | |
| SRP193095 | MED24 | 9862 | RNAseq | 0.1724 | 0.0962 | |
| SRP219564 | MED24 | 9862 | RNAseq | 0.3808 | 0.1456 | |
| TCGA | MED24 | 9862 | RNAseq | 0.0442 | 0.3320 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by MED24 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MED24:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MED24 | 9862 | 9 | 1 | 20 | |
| GSE20123 | MED24 | 9862 | 9 | 1 | 20 | |
| GSE43470 | MED24 | 9862 | 1 | 2 | 40 | |
| GSE46452 | MED24 | 9862 | 34 | 0 | 25 | |
| GSE47630 | MED24 | 9862 | 8 | 1 | 31 | |
| GSE54993 | MED24 | 9862 | 3 | 4 | 63 | |
| GSE54994 | MED24 | 9862 | 9 | 5 | 39 | |
| GSE60625 | MED24 | 9862 | 4 | 0 | 7 | |
| GSE74703 | MED24 | 9862 | 1 | 1 | 34 | |
| GSE74704 | MED24 | 9862 | 5 | 1 | 14 | |
| TCGA | MED24 | 9862 | 23 | 8 | 65 |
Total number of gains: 106; Total number of losses: 24; Total Number of normals: 358.
Somatic mutations of MED24:
Generating mutation plots.
Highly correlated genes for MED24:
Showing top 20/659 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MED24 | TP53I11 | 0.786067 | 3 | 0 | 3 |
| MED24 | BUB1 | 0.785526 | 3 | 0 | 3 |
| MED24 | KCNV1 | 0.778696 | 3 | 0 | 3 |
| MED24 | BMP6 | 0.751698 | 3 | 0 | 3 |
| MED24 | TMED8 | 0.740986 | 3 | 0 | 3 |
| MED24 | MTAP | 0.740982 | 5 | 0 | 5 |
| MED24 | TSHR | 0.731776 | 5 | 0 | 5 |
| MED24 | TP53I13 | 0.727423 | 3 | 0 | 3 |
| MED24 | WT1 | 0.719637 | 4 | 0 | 4 |
| MED24 | DNAH3 | 0.719265 | 4 | 0 | 4 |
| MED24 | CHD1L | 0.718885 | 3 | 0 | 3 |
| MED24 | BTBD2 | 0.716294 | 3 | 0 | 3 |
| MED24 | PDE7A | 0.714934 | 3 | 0 | 3 |
| MED24 | CPA2 | 0.712456 | 3 | 0 | 3 |
| MED24 | CD19 | 0.71129 | 3 | 0 | 3 |
| MED24 | IFNA17 | 0.709138 | 4 | 0 | 4 |
| MED24 | ANKFY1 | 0.7072 | 4 | 0 | 4 |
| MED24 | APBB1IP | 0.706504 | 4 | 0 | 3 |
| MED24 | VAX2 | 0.703338 | 3 | 0 | 3 |
| MED24 | ALS2 | 0.698958 | 3 | 0 | 3 |
For details and further investigation, click here
