| Full name: V-set and immunoglobulin domain containing 8 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 1q23.2 | ||
| Entrez ID: 391123 | HGNC ID: HGNC:32063 | Ensembl Gene: ENSG00000243284 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of VSIG8:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | VSIG8 | 391123 | 59890 | 0.0144 | 0.9274 | |
| GSE53624 | VSIG8 | 391123 | 59890 | -0.5780 | 0.0000 | |
| GSE97050 | VSIG8 | 391123 | A_33_P3393684 | -0.1288 | 0.5990 | |
| SRP007169 | VSIG8 | 391123 | RNAseq | -6.2430 | 0.0000 | |
| SRP008496 | VSIG8 | 391123 | RNAseq | -2.2780 | 0.1412 | |
| SRP064894 | VSIG8 | 391123 | RNAseq | -1.5974 | 0.0012 | |
| SRP133303 | VSIG8 | 391123 | RNAseq | -1.6691 | 0.0028 | |
| SRP159526 | VSIG8 | 391123 | RNAseq | 0.3880 | 0.7072 | |
| SRP219564 | VSIG8 | 391123 | RNAseq | -3.1907 | 0.0006 | |
| TCGA | VSIG8 | 391123 | RNAseq | -0.1410 | 0.7959 |
Upregulated datasets: 0; Downregulated datasets: 4.
Survival by VSIG8 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of VSIG8:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | VSIG8 | 391123 | 10 | 0 | 20 | |
| GSE20123 | VSIG8 | 391123 | 10 | 0 | 20 | |
| GSE43470 | VSIG8 | 391123 | 7 | 2 | 34 | |
| GSE46452 | VSIG8 | 391123 | 2 | 1 | 56 | |
| GSE47630 | VSIG8 | 391123 | 14 | 0 | 26 | |
| GSE54993 | VSIG8 | 391123 | 0 | 5 | 65 | |
| GSE54994 | VSIG8 | 391123 | 16 | 0 | 37 | |
| GSE60625 | VSIG8 | 391123 | 0 | 0 | 11 | |
| GSE74703 | VSIG8 | 391123 | 7 | 2 | 27 | |
| GSE74704 | VSIG8 | 391123 | 4 | 0 | 16 | |
| TCGA | VSIG8 | 391123 | 43 | 3 | 50 |
Total number of gains: 113; Total number of losses: 13; Total Number of normals: 362.
Somatic mutations of VSIG8:
Generating mutation plots.
Highly correlated genes for VSIG8:
Showing top 20/39 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| VSIG8 | KIR3DL2 | 0.79361 | 3 | 0 | 3 |
| VSIG8 | CCIN | 0.724611 | 3 | 0 | 3 |
| VSIG8 | TMEM150A | 0.71732 | 3 | 0 | 3 |
| VSIG8 | VAX2 | 0.716937 | 3 | 0 | 3 |
| VSIG8 | SLC36A4 | 0.710768 | 3 | 0 | 3 |
| VSIG8 | CALY | 0.708745 | 3 | 0 | 3 |
| VSIG8 | ARHGEF33 | 0.703614 | 3 | 0 | 3 |
| VSIG8 | APOB | 0.703294 | 3 | 0 | 3 |
| VSIG8 | SENP1 | 0.68475 | 3 | 0 | 3 |
| VSIG8 | UTF1 | 0.683342 | 3 | 0 | 3 |
| VSIG8 | LHX3 | 0.681591 | 3 | 0 | 3 |
| VSIG8 | CDH24 | 0.680959 | 3 | 0 | 3 |
| VSIG8 | RBPJL | 0.676095 | 3 | 0 | 3 |
| VSIG8 | SLC4A8 | 0.674379 | 3 | 0 | 3 |
| VSIG8 | CCDC154 | 0.671236 | 3 | 0 | 3 |
| VSIG8 | TP53AIP1 | 0.670977 | 3 | 0 | 3 |
| VSIG8 | CELA3A | 0.661282 | 3 | 0 | 3 |
| VSIG8 | EXD3 | 0.66122 | 3 | 0 | 3 |
| VSIG8 | PFKFB2 | 0.657464 | 4 | 0 | 3 |
| VSIG8 | PLXNB3 | 0.651252 | 3 | 0 | 3 |
For details and further investigation, click here
