| Full name: eukaryotic translation initiation factor 3 subunit G | Alias Symbol: eIF3-delta|eIF3-p44|eIF3g | ||
| Type: protein-coding gene | Cytoband: 19p13.2 | ||
| Entrez ID: 8666 | HGNC ID: HGNC:3274 | Ensembl Gene: | OMIM ID: 603913 |
| Drug and gene relationship at DGIdb | |||
Expression of EIF3G:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | EIF3G | 8666 | 208887_at | -0.0534 | 0.8947 | |
| GSE20347 | EIF3G | 8666 | 208887_at | -0.0739 | 0.6606 | |
| GSE23400 | EIF3G | 8666 | 208887_at | 0.2103 | 0.0051 | |
| GSE26886 | EIF3G | 8666 | 208887_at | 1.2897 | 0.0000 | |
| GSE29001 | EIF3G | 8666 | 208887_at | 0.3385 | 0.5058 | |
| GSE38129 | EIF3G | 8666 | 208887_at | -0.0560 | 0.6464 | |
| GSE45670 | EIF3G | 8666 | 208887_at | 0.0897 | 0.5392 | |
| GSE53622 | EIF3G | 8666 | 94225 | -0.1481 | 0.0089 | |
| GSE53624 | EIF3G | 8666 | 94225 | 0.1207 | 0.1129 | |
| GSE63941 | EIF3G | 8666 | 208887_at | 0.6277 | 0.0987 | |
| GSE77861 | EIF3G | 8666 | 208887_at | 0.4293 | 0.0512 | |
| GSE97050 | EIF3G | 8666 | A_33_P3369581 | -0.5228 | 0.1133 | |
| SRP007169 | EIF3G | 8666 | RNAseq | -0.4072 | 0.2024 | |
| SRP008496 | EIF3G | 8666 | RNAseq | -0.2970 | 0.0956 | |
| SRP064894 | EIF3G | 8666 | RNAseq | 0.2653 | 0.3795 | |
| SRP133303 | EIF3G | 8666 | RNAseq | -0.0621 | 0.7175 | |
| SRP159526 | EIF3G | 8666 | RNAseq | -0.1683 | 0.2812 | |
| SRP193095 | EIF3G | 8666 | RNAseq | -0.0396 | 0.6845 | |
| TCGA | EIF3G | 8666 | RNAseq | -0.0174 | 0.7047 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by EIF3G expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of EIF3G:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | EIF3G | 8666 | 4 | 2 | 24 | |
| GSE20123 | EIF3G | 8666 | 3 | 1 | 26 | |
| GSE43470 | EIF3G | 8666 | 3 | 6 | 34 | |
| GSE46452 | EIF3G | 8666 | 47 | 1 | 11 | |
| GSE47630 | EIF3G | 8666 | 4 | 7 | 29 | |
| GSE54993 | EIF3G | 8666 | 16 | 3 | 51 | |
| GSE54994 | EIF3G | 8666 | 7 | 13 | 33 | |
| GSE60625 | EIF3G | 8666 | 9 | 0 | 2 | |
| GSE74703 | EIF3G | 8666 | 3 | 4 | 29 | |
| GSE74704 | EIF3G | 8666 | 0 | 1 | 19 | |
| TCGA | EIF3G | 8666 | 13 | 16 | 67 |
Total number of gains: 109; Total number of losses: 54; Total Number of normals: 325.
Somatic mutations of EIF3G:
Generating mutation plots.
Highly correlated genes for EIF3G:
Showing top 20/1029 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| EIF3G | GATC | 0.844501 | 3 | 0 | 3 |
| EIF3G | LNP1 | 0.829872 | 3 | 0 | 3 |
| EIF3G | BOD1 | 0.801689 | 5 | 0 | 5 |
| EIF3G | RNASEH2C | 0.796966 | 3 | 0 | 3 |
| EIF3G | RBM18 | 0.788814 | 3 | 0 | 3 |
| EIF3G | ZBTB26 | 0.779622 | 3 | 0 | 3 |
| EIF3G | MMP15 | 0.774571 | 3 | 0 | 3 |
| EIF3G | CBLL1 | 0.770822 | 3 | 0 | 3 |
| EIF3G | RSRC2 | 0.761739 | 3 | 0 | 3 |
| EIF3G | LDB1 | 0.760241 | 3 | 0 | 3 |
| EIF3G | NUB1 | 0.759435 | 3 | 0 | 3 |
| EIF3G | TSNARE1 | 0.751344 | 3 | 0 | 3 |
| EIF3G | MED9 | 0.751104 | 3 | 0 | 3 |
| EIF3G | SOBP | 0.750076 | 3 | 0 | 3 |
| EIF3G | ZCCHC17 | 0.746767 | 3 | 0 | 3 |
| EIF3G | KIAA1328 | 0.746756 | 3 | 0 | 3 |
| EIF3G | BBX | 0.740459 | 5 | 0 | 5 |
| EIF3G | IRS2 | 0.739565 | 4 | 0 | 3 |
| EIF3G | GPC4 | 0.737955 | 3 | 0 | 3 |
| EIF3G | PLEKHA3 | 0.73414 | 3 | 0 | 3 |
For details and further investigation, click here
