| Full name: vacuolar protein sorting 13 homolog A | Alias Symbol: KIAA0986 | ||
| Type: protein-coding gene | Cytoband: 9q21.2 | ||
| Entrez ID: 23230 | HGNC ID: HGNC:1908 | Ensembl Gene: ENSG00000197969 | OMIM ID: 605978 |
| Drug and gene relationship at DGIdb | |||
Expression of VPS13A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | VPS13A | 23230 | 227987_at | -0.4417 | 0.3228 | |
| GSE20347 | VPS13A | 23230 | 214785_at | -0.1222 | 0.5266 | |
| GSE23400 | VPS13A | 23230 | 213686_at | -0.0387 | 0.4470 | |
| GSE26886 | VPS13A | 23230 | 227987_at | -0.6461 | 0.0247 | |
| GSE29001 | VPS13A | 23230 | 213686_at | 0.0313 | 0.9257 | |
| GSE38129 | VPS13A | 23230 | 214785_at | 0.0757 | 0.8220 | |
| GSE45670 | VPS13A | 23230 | 227987_at | -0.3461 | 0.0984 | |
| GSE53622 | VPS13A | 23230 | 16894 | -0.6075 | 0.0000 | |
| GSE53624 | VPS13A | 23230 | 16894 | -0.5896 | 0.0000 | |
| GSE63941 | VPS13A | 23230 | 227988_s_at | -0.8385 | 0.2410 | |
| GSE77861 | VPS13A | 23230 | 227988_s_at | -0.2903 | 0.4146 | |
| GSE97050 | VPS13A | 23230 | A_23_P217098 | -0.8269 | 0.0620 | |
| SRP007169 | VPS13A | 23230 | RNAseq | 0.7906 | 0.0161 | |
| SRP008496 | VPS13A | 23230 | RNAseq | 0.7823 | 0.0002 | |
| SRP064894 | VPS13A | 23230 | RNAseq | -0.4967 | 0.1354 | |
| SRP133303 | VPS13A | 23230 | RNAseq | -0.3505 | 0.0664 | |
| SRP159526 | VPS13A | 23230 | RNAseq | -0.9836 | 0.0000 | |
| SRP193095 | VPS13A | 23230 | RNAseq | -0.6509 | 0.0000 | |
| SRP219564 | VPS13A | 23230 | RNAseq | -1.0158 | 0.0003 | |
| TCGA | VPS13A | 23230 | RNAseq | -0.2506 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by VPS13A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of VPS13A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | VPS13A | 23230 | 6 | 10 | 14 | |
| GSE20123 | VPS13A | 23230 | 6 | 10 | 14 | |
| GSE43470 | VPS13A | 23230 | 6 | 5 | 32 | |
| GSE46452 | VPS13A | 23230 | 6 | 14 | 39 | |
| GSE47630 | VPS13A | 23230 | 1 | 18 | 21 | |
| GSE54993 | VPS13A | 23230 | 4 | 2 | 64 | |
| GSE54994 | VPS13A | 23230 | 4 | 12 | 37 | |
| GSE60625 | VPS13A | 23230 | 0 | 0 | 11 | |
| GSE74703 | VPS13A | 23230 | 5 | 4 | 27 | |
| GSE74704 | VPS13A | 23230 | 3 | 7 | 10 | |
| TCGA | VPS13A | 23230 | 19 | 28 | 49 |
Total number of gains: 60; Total number of losses: 110; Total Number of normals: 318.
Somatic mutations of VPS13A:
Generating mutation plots.
Highly correlated genes for VPS13A:
Showing top 20/618 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| VPS13A | RBAK | 0.723195 | 3 | 0 | 3 |
| VPS13A | B4GALT5 | 0.718018 | 3 | 0 | 3 |
| VPS13A | ROGDI | 0.715602 | 3 | 0 | 3 |
| VPS13A | B3GAT2 | 0.712713 | 3 | 0 | 3 |
| VPS13A | FAM120B | 0.706527 | 3 | 0 | 3 |
| VPS13A | ZNF608 | 0.703076 | 3 | 0 | 3 |
| VPS13A | GUF1 | 0.698766 | 5 | 0 | 5 |
| VPS13A | SNX14 | 0.698474 | 3 | 0 | 3 |
| VPS13A | VMAC | 0.693463 | 3 | 0 | 3 |
| VPS13A | CREB1 | 0.689481 | 3 | 0 | 3 |
| VPS13A | WIPF2 | 0.68706 | 3 | 0 | 3 |
| VPS13A | ZNF347 | 0.684732 | 3 | 0 | 3 |
| VPS13A | ZNF844 | 0.680639 | 5 | 0 | 5 |
| VPS13A | OSBPL8 | 0.678248 | 4 | 0 | 3 |
| VPS13A | OPHN1 | 0.676294 | 5 | 0 | 4 |
| VPS13A | SAMD9L | 0.674785 | 3 | 0 | 3 |
| VPS13A | WDTC1 | 0.674373 | 3 | 0 | 3 |
| VPS13A | USP47 | 0.674257 | 5 | 0 | 5 |
| VPS13A | FBXW5 | 0.673484 | 4 | 0 | 4 |
| VPS13A | KLHDC1 | 0.672881 | 4 | 0 | 4 |
For details and further investigation, click here
