| Full name: sorting nexin 14 | Alias Symbol: RGS-PX2 | ||
| Type: protein-coding gene | Cytoband: 6q14.3 | ||
| Entrez ID: 57231 | HGNC ID: HGNC:14977 | Ensembl Gene: ENSG00000135317 | OMIM ID: 616105 |
| Drug and gene relationship at DGIdb | |||
Expression of SNX14:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SNX14 | 57231 | 225101_s_at | -0.4423 | 0.3542 | |
| GSE26886 | SNX14 | 57231 | 225101_s_at | -0.1130 | 0.7294 | |
| GSE45670 | SNX14 | 57231 | 225101_s_at | -0.0540 | 0.7251 | |
| GSE53622 | SNX14 | 57231 | 33494 | -0.0471 | 0.5351 | |
| GSE53624 | SNX14 | 57231 | 33494 | -0.2499 | 0.0005 | |
| GSE63941 | SNX14 | 57231 | 225101_s_at | -0.6387 | 0.3563 | |
| GSE77861 | SNX14 | 57231 | 225101_s_at | -0.2040 | 0.1790 | |
| GSE97050 | SNX14 | 57231 | A_23_P259054 | 0.1832 | 0.5499 | |
| SRP007169 | SNX14 | 57231 | RNAseq | -0.1180 | 0.7107 | |
| SRP008496 | SNX14 | 57231 | RNAseq | -0.0250 | 0.9063 | |
| SRP064894 | SNX14 | 57231 | RNAseq | 0.1185 | 0.3986 | |
| SRP133303 | SNX14 | 57231 | RNAseq | 0.0477 | 0.7325 | |
| SRP159526 | SNX14 | 57231 | RNAseq | -0.3445 | 0.3012 | |
| SRP193095 | SNX14 | 57231 | RNAseq | -0.4684 | 0.0036 | |
| SRP219564 | SNX14 | 57231 | RNAseq | -0.3632 | 0.2625 | |
| TCGA | SNX14 | 57231 | RNAseq | -0.2094 | 0.0001 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SNX14 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SNX14:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SNX14 | 57231 | 1 | 4 | 25 | |
| GSE20123 | SNX14 | 57231 | 1 | 3 | 26 | |
| GSE43470 | SNX14 | 57231 | 2 | 1 | 40 | |
| GSE46452 | SNX14 | 57231 | 2 | 11 | 46 | |
| GSE47630 | SNX14 | 57231 | 8 | 6 | 26 | |
| GSE54993 | SNX14 | 57231 | 3 | 2 | 65 | |
| GSE54994 | SNX14 | 57231 | 8 | 8 | 37 | |
| GSE60625 | SNX14 | 57231 | 0 | 1 | 10 | |
| GSE74703 | SNX14 | 57231 | 2 | 1 | 33 | |
| GSE74704 | SNX14 | 57231 | 0 | 2 | 18 | |
| TCGA | SNX14 | 57231 | 6 | 21 | 69 |
Total number of gains: 33; Total number of losses: 60; Total Number of normals: 395.
Somatic mutations of SNX14:
Generating mutation plots.
Highly correlated genes for SNX14:
Showing top 20/308 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SNX14 | C11orf54 | 0.835151 | 3 | 0 | 3 |
| SNX14 | PHLDA1 | 0.831569 | 3 | 0 | 3 |
| SNX14 | SPTLC3 | 0.806911 | 3 | 0 | 3 |
| SNX14 | SCAPER | 0.799 | 3 | 0 | 3 |
| SNX14 | GNB4 | 0.783637 | 3 | 0 | 3 |
| SNX14 | AREG | 0.781537 | 3 | 0 | 3 |
| SNX14 | JMJD1C | 0.771384 | 3 | 0 | 3 |
| SNX14 | POLD4 | 0.767429 | 3 | 0 | 3 |
| SNX14 | GAPVD1 | 0.767022 | 4 | 0 | 4 |
| SNX14 | C5orf24 | 0.758952 | 3 | 0 | 3 |
| SNX14 | DNAJA2 | 0.746174 | 3 | 0 | 3 |
| SNX14 | PPP1R2 | 0.743872 | 3 | 0 | 3 |
| SNX14 | OSBPL10 | 0.742565 | 4 | 0 | 3 |
| SNX14 | PURA | 0.7372 | 3 | 0 | 3 |
| SNX14 | ZNF33A | 0.733926 | 3 | 0 | 3 |
| SNX14 | PPP1R3B | 0.729855 | 3 | 0 | 3 |
| SNX14 | KLHDC10 | 0.727614 | 3 | 0 | 3 |
| SNX14 | PLK2 | 0.726468 | 3 | 0 | 3 |
| SNX14 | SESN2 | 0.724911 | 3 | 0 | 3 |
| SNX14 | ANKHD1 | 0.72252 | 3 | 0 | 3 |
For details and further investigation, click here
