B3GAT2

 

Full name: beta-1,3-glucuronyltransferase 2 Alias Symbol: GlcAT-S
Type: protein-coding gene Cytoband: 6q13
Entrez ID: 135152 HGNC ID: HGNC:922 Ensembl Gene: ENSG00000112309 OMIM ID: 607497
Drug and gene relationship at DGIdb

 

Expression of B3GAT2:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 B3GAT2 135152 239144_at -0.4411 0.5119
GSE26886 B3GAT2 135152 239144_at -0.4720 0.0417
GSE45670 B3GAT2 135152 239144_at -0.4430 0.0073
GSE53622 B3GAT2 135152 73202 -0.6294 0.0000
GSE53624 B3GAT2 135152 73202 -0.6024 0.0000
GSE63941 B3GAT2 135152 239144_at 0.8164 0.0249
GSE77861 B3GAT2 135152 239144_at -0.1055 0.3888
GSE97050 B3GAT2 135152 A_23_P167805 -0.7241 0.0705
SRP133303 B3GAT2 135152 RNAseq -0.2772 0.1275
SRP159526 B3GAT2 135152 RNAseq -0.1292 0.7719
SRP193095 B3GAT2 135152 RNAseq -0.8642 0.0000
SRP219564 B3GAT2 135152 RNAseq -0.1886 0.7299
TCGA B3GAT2 135152 RNAseq -0.5236 0.0212

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by B3GAT2 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of B3GAT2:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 B3GAT2 135152 2 2 26
GSE20123 B3GAT2 135152 2 1 27
GSE43470 B3GAT2 135152 3 0 40
GSE46452 B3GAT2 135152 2 11 46
GSE47630 B3GAT2 135152 8 4 28
GSE54993 B3GAT2 135152 3 2 65
GSE54994 B3GAT2 135152 9 5 39
GSE60625 B3GAT2 135152 0 2 9
GSE74703 B3GAT2 135152 3 0 33
GSE74704 B3GAT2 135152 0 1 19
TCGA B3GAT2 135152 11 19 66

Total number of gains: 43; Total number of losses: 47; Total Number of normals: 398.  


 

Somatic mutations of B3GAT2:

 

Generating mutation plots.

 

Highly correlated genes for B3GAT2:

 

Showing top 20/111 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
B3GAT2MTA30.754933303
B3GAT2PDZRN40.746725303
B3GAT2MAP2K70.73878303
B3GAT2VPS13A0.712713303
B3GAT2PRKAG10.711304303
B3GAT2HEXIM10.700052303
B3GAT2SMYD10.693833303
B3GAT2DNHD10.688885303
B3GAT2B3GNT20.684902303
B3GAT2PRKAB10.679916303
B3GAT2KCNG20.675771303
B3GAT2TBC1D250.672437303
B3GAT2GAS80.671749303
B3GAT2SLC26A100.668857303
B3GAT2FAM8A10.663918303
B3GAT2ZNF2070.663847303
B3GAT2ZCCHC80.659298303
B3GAT2TPRKB0.657596303
B3GAT2SPATA20.651737303
B3GAT2TNFSF140.645792303

For details and further investigation, click here