| Full name: RB associated KRAB zinc finger | Alias Symbol: ZNF769 | ||
| Type: protein-coding gene | Cytoband: 7p22.1 | ||
| Entrez ID: 57786 | HGNC ID: HGNC:17680 | Ensembl Gene: ENSG00000146587 | OMIM ID: 608191 |
| Drug and gene relationship at DGIdb | |||
Expression of RBAK:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RBAK | 57786 | 228571_at | -0.1782 | 0.7237 | |
| GSE26886 | RBAK | 57786 | 228571_at | -0.1063 | 0.7159 | |
| GSE45670 | RBAK | 57786 | 228571_at | 0.0443 | 0.7395 | |
| GSE53622 | RBAK | 57786 | 103972 | 0.3241 | 0.0000 | |
| GSE53624 | RBAK | 57786 | 103972 | 0.0614 | 0.4385 | |
| GSE63941 | RBAK | 57786 | 228571_at | 0.3632 | 0.6016 | |
| GSE77861 | RBAK | 57786 | 228571_at | -0.0803 | 0.7740 | |
| GSE97050 | RBAK | 57786 | A_24_P72394 | 0.1789 | 0.7895 | |
| SRP007169 | RBAK | 57786 | RNAseq | 0.1636 | 0.6888 | |
| SRP008496 | RBAK | 57786 | RNAseq | 0.5120 | 0.0612 | |
| SRP064894 | RBAK | 57786 | RNAseq | -0.1877 | 0.4348 | |
| SRP133303 | RBAK | 57786 | RNAseq | 0.2222 | 0.1347 | |
| SRP159526 | RBAK | 57786 | RNAseq | 0.0369 | 0.8489 | |
| SRP193095 | RBAK | 57786 | RNAseq | -0.1981 | 0.0867 | |
| SRP219564 | RBAK | 57786 | RNAseq | -0.2609 | 0.4905 | |
| TCGA | RBAK | 57786 | RNAseq | 0.0903 | 0.0821 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by RBAK expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RBAK:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RBAK | 57786 | 14 | 1 | 15 | |
| GSE20123 | RBAK | 57786 | 14 | 1 | 15 | |
| GSE43470 | RBAK | 57786 | 6 | 1 | 36 | |
| GSE46452 | RBAK | 57786 | 13 | 1 | 45 | |
| GSE47630 | RBAK | 57786 | 9 | 1 | 30 | |
| GSE54993 | RBAK | 57786 | 0 | 6 | 64 | |
| GSE54994 | RBAK | 57786 | 22 | 2 | 29 | |
| GSE60625 | RBAK | 57786 | 0 | 0 | 11 | |
| GSE74703 | RBAK | 57786 | 6 | 0 | 30 | |
| GSE74704 | RBAK | 57786 | 9 | 0 | 11 | |
| TCGA | RBAK | 57786 | 56 | 5 | 35 |
Total number of gains: 149; Total number of losses: 18; Total Number of normals: 321.
Somatic mutations of RBAK:
Generating mutation plots.
Highly correlated genes for RBAK:
Showing top 20/223 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RBAK | ATP11B | 0.79637 | 3 | 0 | 3 |
| RBAK | CTR9 | 0.79307 | 3 | 0 | 3 |
| RBAK | ZNF207 | 0.776862 | 3 | 0 | 3 |
| RBAK | IREB2 | 0.769987 | 4 | 0 | 4 |
| RBAK | SIAE | 0.766042 | 3 | 0 | 3 |
| RBAK | SLC35E3 | 0.765128 | 3 | 0 | 3 |
| RBAK | SAR1A | 0.757459 | 3 | 0 | 3 |
| RBAK | C6orf120 | 0.747165 | 4 | 0 | 4 |
| RBAK | BTBD1 | 0.742547 | 3 | 0 | 3 |
| RBAK | RNFT1 | 0.741194 | 3 | 0 | 3 |
| RBAK | PLEKHG1 | 0.740008 | 3 | 0 | 3 |
| RBAK | LRIG3 | 0.739711 | 3 | 0 | 3 |
| RBAK | ZNF140 | 0.736039 | 3 | 0 | 3 |
| RBAK | MFAP1 | 0.731241 | 3 | 0 | 3 |
| RBAK | UBQLN1 | 0.727169 | 3 | 0 | 3 |
| RBAK | VPS13A | 0.723195 | 3 | 0 | 3 |
| RBAK | IQGAP1 | 0.72252 | 3 | 0 | 3 |
| RBAK | RFX7 | 0.722387 | 3 | 0 | 3 |
| RBAK | SCRN3 | 0.720234 | 3 | 0 | 3 |
| RBAK | SLC12A6 | 0.719816 | 3 | 0 | 3 |
For details and further investigation, click here
