| Full name: HYDIN axonemal central pair apparatus protein | Alias Symbol: DKFZp434D0513|KIAA1864|PPP1R31|CILD5 | ||
| Type: protein-coding gene | Cytoband: 16q22.2 | ||
| Entrez ID: 54768 | HGNC ID: HGNC:19368 | Ensembl Gene: ENSG00000157423 | OMIM ID: 610812 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of HYDIN:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HYDIN | 54768 | 1554908_at | -0.0888 | 0.7196 | |
| GSE26886 | HYDIN | 54768 | 1554908_at | 0.0172 | 0.8709 | |
| GSE45670 | HYDIN | 54768 | 1554908_at | -0.1134 | 0.0979 | |
| GSE53622 | HYDIN | 54768 | 102001 | 0.5788 | 0.0017 | |
| GSE53624 | HYDIN | 54768 | 102001 | 0.8601 | 0.0000 | |
| GSE63941 | HYDIN | 54768 | 1554908_at | 0.0410 | 0.7492 | |
| GSE77861 | HYDIN | 54768 | 1554908_at | -0.0728 | 0.4095 | |
| GSE97050 | HYDIN | 54768 | A_33_P3300232 | 0.0532 | 0.9090 | |
| SRP133303 | HYDIN | 54768 | RNAseq | -0.0435 | 0.8965 | |
| SRP159526 | HYDIN | 54768 | RNAseq | 0.4126 | 0.5579 | |
| SRP193095 | HYDIN | 54768 | RNAseq | 0.6111 | 0.0575 | |
| TCGA | HYDIN | 54768 | RNAseq | -0.0487 | 0.8879 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by HYDIN expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of HYDIN:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HYDIN | 54768 | 5 | 0 | 25 | |
| GSE20123 | HYDIN | 54768 | 5 | 0 | 25 | |
| GSE43470 | HYDIN | 54768 | 2 | 8 | 33 | |
| GSE46452 | HYDIN | 54768 | 38 | 2 | 19 | |
| GSE47630 | HYDIN | 54768 | 11 | 8 | 21 | |
| GSE54993 | HYDIN | 54768 | 2 | 4 | 64 | |
| GSE54994 | HYDIN | 54768 | 8 | 10 | 35 | |
| GSE60625 | HYDIN | 54768 | 4 | 0 | 7 | |
| GSE74703 | HYDIN | 54768 | 2 | 5 | 29 | |
| GSE74704 | HYDIN | 54768 | 2 | 0 | 18 | |
| TCGA | HYDIN | 54768 | 28 | 12 | 56 |
Total number of gains: 107; Total number of losses: 49; Total Number of normals: 332.
Somatic mutations of HYDIN:
Generating mutation plots.
Highly correlated genes for HYDIN:
Showing all 17 correlated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HYDIN | VSX1 | 0.707121 | 3 | 0 | 3 |
| HYDIN | RND1 | 0.65631 | 3 | 0 | 3 |
| HYDIN | MBLAC1 | 0.653766 | 3 | 0 | 3 |
| HYDIN | USP29 | 0.646236 | 3 | 0 | 3 |
| HYDIN | CT62 | 0.611128 | 3 | 0 | 3 |
| HYDIN | ESRRG | 0.603589 | 3 | 0 | 3 |
| HYDIN | SULT1C2 | 0.600313 | 3 | 0 | 3 |
| HYDIN | C15orf41 | 0.593483 | 3 | 0 | 3 |
| HYDIN | ZNF345 | 0.556705 | 4 | 0 | 3 |
| HYDIN | ACAD11 | 0.555273 | 3 | 0 | 3 |
| HYDIN | NRXN2 | 0.547186 | 4 | 0 | 3 |
| HYDIN | PRDM14 | 0.540551 | 3 | 0 | 3 |
| HYDIN | PARD3B | 0.534272 | 4 | 0 | 3 |
| HYDIN | TNFRSF10C | 0.534022 | 5 | 0 | 3 |
| HYDIN | HHLA1 | 0.533866 | 3 | 0 | 3 |
| HYDIN | CNTNAP3 | 0.517254 | 4 | 0 | 3 |
| HYDIN | SOX10 | 0.512793 | 4 | 0 | 3 |
For details and further investigation, click here
