| Full name: TBC1 domain family member 21 | Alias Symbol: MGC34741|MgcRabGAP | ||
| Type: protein-coding gene | Cytoband: 15q24.1 | ||
| Entrez ID: 161514 | HGNC ID: HGNC:28536 | Ensembl Gene: ENSG00000167139 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of TBC1D21:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TBC1D21 | 161514 | 231475_at | -0.1507 | 0.5041 | |
| GSE26886 | TBC1D21 | 161514 | 231475_at | -0.0504 | 0.7356 | |
| GSE45670 | TBC1D21 | 161514 | 231475_at | -0.0686 | 0.6035 | |
| GSE53622 | TBC1D21 | 161514 | 94966 | -0.3444 | 0.0017 | |
| GSE53624 | TBC1D21 | 161514 | 94966 | 0.0045 | 0.9535 | |
| GSE63941 | TBC1D21 | 161514 | 231475_at | 0.2787 | 0.0607 | |
| GSE77861 | TBC1D21 | 161514 | 231475_at | -0.1460 | 0.2390 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TBC1D21 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of TBC1D21:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TBC1D21 | 161514 | 8 | 0 | 22 | |
| GSE20123 | TBC1D21 | 161514 | 8 | 0 | 22 | |
| GSE43470 | TBC1D21 | 161514 | 4 | 6 | 33 | |
| GSE46452 | TBC1D21 | 161514 | 3 | 7 | 49 | |
| GSE47630 | TBC1D21 | 161514 | 8 | 10 | 22 | |
| GSE54993 | TBC1D21 | 161514 | 5 | 6 | 59 | |
| GSE54994 | TBC1D21 | 161514 | 5 | 7 | 41 | |
| GSE60625 | TBC1D21 | 161514 | 4 | 0 | 7 | |
| GSE74703 | TBC1D21 | 161514 | 4 | 3 | 29 | |
| GSE74704 | TBC1D21 | 161514 | 4 | 0 | 16 | |
| TCGA | TBC1D21 | 161514 | 13 | 15 | 68 |
Total number of gains: 66; Total number of losses: 54; Total Number of normals: 368.
Somatic mutations of TBC1D21:
Generating mutation plots.
Highly correlated genes for TBC1D21:
Showing top 20/161 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TBC1D21 | PSG5 | 0.723348 | 3 | 0 | 3 |
| TBC1D21 | CHIA | 0.703412 | 3 | 0 | 3 |
| TBC1D21 | GPR137 | 0.696911 | 3 | 0 | 3 |
| TBC1D21 | KCNK17 | 0.677572 | 3 | 0 | 3 |
| TBC1D21 | ARMC4 | 0.654344 | 3 | 0 | 3 |
| TBC1D21 | LRRC46 | 0.653582 | 3 | 0 | 3 |
| TBC1D21 | VSX1 | 0.648537 | 4 | 0 | 4 |
| TBC1D21 | SLC6A1 | 0.640501 | 3 | 0 | 3 |
| TBC1D21 | GPR182 | 0.63621 | 3 | 0 | 3 |
| TBC1D21 | ATP4A | 0.634375 | 3 | 0 | 3 |
| TBC1D21 | C20orf173 | 0.633902 | 4 | 0 | 4 |
| TBC1D21 | KRTAP4-8 | 0.630728 | 4 | 0 | 3 |
| TBC1D21 | NAA20 | 0.627881 | 3 | 0 | 3 |
| TBC1D21 | CACNG8 | 0.626566 | 5 | 0 | 3 |
| TBC1D21 | DCT | 0.623547 | 4 | 0 | 4 |
| TBC1D21 | RHOG | 0.619376 | 3 | 0 | 3 |
| TBC1D21 | ADRB3 | 0.618146 | 3 | 0 | 3 |
| TBC1D21 | MYL7 | 0.618119 | 3 | 0 | 3 |
| TBC1D21 | OR2C3 | 0.615974 | 3 | 0 | 3 |
| TBC1D21 | MSH4 | 0.614463 | 3 | 0 | 3 |
For details and further investigation, click here
