NSMF

 

Full name: NMDA receptor synaptonuclear signaling and neuronal migration factor Alias Symbol: 
Type: protein-coding gene Cytoband: 9q34.3
Entrez ID: 26012 HGNC ID: HGNC:29843 Ensembl Gene: ENSG00000165802 OMIM ID: 608137
Drug and gene relationship at DGIdb
Screen Evidence:
  • Knocking out of this gene by CRIPR/Cas9 screen found altered tolerance on DNA toxicity in Genotoxic Screens.

 

Expression of NSMF:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 NSMF 26012 230189_x_at 0.0564 0.8577
GSE26886 NSMF 26012 230189_x_at 0.3778 0.0026
GSE45670 NSMF 26012 230189_x_at -0.0049 0.9648
GSE53622 NSMF 26012 12386 0.8790 0.0000
GSE53624 NSMF 26012 12386 0.9209 0.0000
GSE63941 NSMF 26012 230189_x_at -0.0234 0.8851
GSE77861 NSMF 26012 230189_x_at -0.0210 0.8586
SRP007169 NSMF 26012 RNAseq 0.7094 0.1423
SRP008496 NSMF 26012 RNAseq 0.6860 0.0239
SRP064894 NSMF 26012 RNAseq 0.7033 0.0005
SRP133303 NSMF 26012 RNAseq 0.5954 0.0016
SRP159526 NSMF 26012 RNAseq 0.7819 0.0594
SRP193095 NSMF 26012 RNAseq 0.7668 0.0000
SRP219564 NSMF 26012 RNAseq 0.2640 0.5521

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by NSMF expression:

 

GSE53622GSE53624

 

Note: Click image to view full size file.  


Copy number change of NSMF:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 NSMF 26012 5 7 18
GSE20123 NSMF 26012 5 7 18
GSE43470 NSMF 26012 3 7 33
GSE46452 NSMF 26012 6 13 40
GSE47630 NSMF 26012 6 15 19
GSE54993 NSMF 26012 3 3 64
GSE54994 NSMF 26012 19 3 31
GSE60625 NSMF 26012 0 0 11
GSE74703 NSMF 26012 3 5 28
GSE74704 NSMF 26012 3 5 12
TCGA NSMF 26012 30 23 43

Total number of gains: 83; Total number of losses: 88; Total Number of normals: 317.  


 

Somatic mutations of NSMF:

 

Generating mutation plots.

 

Highly correlated genes for NSMF:

 

Showing top 20/366 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
NSMFTTC9B0.734914303
NSMFLINC010150.717821303
NSMFNCLN0.703638404
NSMFTP53TG50.699792303
NSMFDNASE1L20.698372303
NSMFACY10.696303
NSMFVSX10.69193303
NSMFMAP1LC3B20.690219303
NSMFINHBA0.688045303
NSMFCHPF0.685971303
NSMFPLEKHG20.684149303
NSMFPRX0.68373303
NSMFCCL70.681437303
NSMFSIX10.680141303
NSMFMYBL20.679744303
NSMFKLC20.679724303
NSMFAUP10.679314303
NSMFBCAS40.679238303
NSMFATP1A30.678967303
NSMFMRGBP0.674026303

For details and further investigation, click here