WDR18

 

Full name: WD repeat domain 18 Alias Symbol: Ipi3
Type: protein-coding gene Cytoband: 19p13.3
Entrez ID: 57418 HGNC ID: HGNC:17956 Ensembl Gene: ENSG00000065268 OMIM ID: 
Drug and gene relationship at DGIdb
Screen Evidence:

 

Expression of WDR18:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 WDR18 57418 209461_x_at 0.6895 0.1581
GSE20347 WDR18 57418 209461_x_at 0.1779 0.1723
GSE23400 WDR18 57418 209461_x_at 0.2673 0.0003
GSE26886 WDR18 57418 209461_x_at 0.4142 0.0024
GSE29001 WDR18 57418 209461_x_at 0.1631 0.3232
GSE38129 WDR18 57418 209461_x_at 0.3564 0.0005
GSE45670 WDR18 57418 209461_x_at 0.5277 0.0001
GSE53622 WDR18 57418 58567 0.2553 0.0095
GSE53624 WDR18 57418 58567 0.6831 0.0000
GSE63941 WDR18 57418 209461_x_at 1.3682 0.0041
GSE77861 WDR18 57418 209461_x_at 0.3256 0.0135
GSE97050 WDR18 57418 A_33_P3411925 0.6592 0.1581
SRP007169 WDR18 57418 RNAseq 0.0598 0.8702
SRP008496 WDR18 57418 RNAseq -0.0905 0.7670
SRP064894 WDR18 57418 RNAseq 0.8178 0.0111
SRP133303 WDR18 57418 RNAseq 0.5014 0.0254
SRP159526 WDR18 57418 RNAseq 0.4906 0.0362
SRP193095 WDR18 57418 RNAseq 0.1681 0.1564
SRP219564 WDR18 57418 RNAseq 0.6750 0.0602
TCGA WDR18 57418 RNAseq 0.3080 0.0000

Upregulated datasets: 1; Downregulated datasets: 0.  

 

Survival by WDR18 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of WDR18:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 WDR18 57418 4 6 20
GSE20123 WDR18 57418 4 5 21
GSE43470 WDR18 57418 1 9 33
GSE46452 WDR18 57418 47 1 11
GSE47630 WDR18 57418 5 7 28
GSE54993 WDR18 57418 13 4 53
GSE54994 WDR18 57418 8 15 30
GSE60625 WDR18 57418 9 0 2
GSE74703 WDR18 57418 1 7 28
GSE74704 WDR18 57418 3 3 14
TCGA WDR18 57418 8 25 63

Total number of gains: 103; Total number of losses: 82; Total Number of normals: 303.  

 

Somatic mutations of WDR18:

 

Generating mutation plots.

 

Highly correlated genes for WDR18:

 

Showing top 20/1041 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
WDR18ZBTB90.745825303
WDR18SLC8B10.724899303
WDR18ALG10.705132504
WDR18RNF260.696565303
WDR18MCMBP0.696442303
WDR18PRR190.69505303
WDR18EAF20.683268404
WDR18CDCA20.678853404
WDR18COMMD20.677553504
WDR18RCC20.673142605
WDR18THAP50.669527303
WDR18BTF3L40.667454303
WDR18ENTPD70.666342504
WDR18ANKRD390.663853303
WDR18DPP30.663255908
WDR18FANCD20.663239505
WDR18INTS90.656754404
WDR18GRAMD1A0.655624404
WDR18PDPR0.653792303
WDR18SCYL10.653597504

For details and further investigation, click here