| Full name: ELL associated factor 2 | Alias Symbol: BM040|TRAITS|U19 | ||
| Type: protein-coding gene | Cytoband: 3q13.33 | ||
| Entrez ID: 55840 | HGNC ID: HGNC:23115 | Ensembl Gene: ENSG00000145088 | OMIM ID: 607659 |
| Drug and gene relationship at DGIdb | |||
Expression of EAF2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | EAF2 | 55840 | 219551_at | 0.4219 | 0.3031 | |
| GSE20347 | EAF2 | 55840 | 219551_at | 0.7766 | 0.0000 | |
| GSE23400 | EAF2 | 55840 | 219551_at | 0.1244 | 0.0048 | |
| GSE26886 | EAF2 | 55840 | 219551_at | 1.4754 | 0.0000 | |
| GSE29001 | EAF2 | 55840 | 219551_at | 0.3393 | 0.3642 | |
| GSE38129 | EAF2 | 55840 | 219551_at | 0.5644 | 0.0053 | |
| GSE45670 | EAF2 | 55840 | 219551_at | 0.6552 | 0.0092 | |
| GSE53622 | EAF2 | 55840 | 80359 | 0.7037 | 0.0000 | |
| GSE53624 | EAF2 | 55840 | 80359 | 0.1966 | 0.1118 | |
| GSE63941 | EAF2 | 55840 | 219551_at | 1.8284 | 0.0220 | |
| GSE77861 | EAF2 | 55840 | 219551_at | 0.4895 | 0.2172 | |
| GSE97050 | EAF2 | 55840 | A_23_P252201 | 1.6275 | 0.0903 | |
| SRP064894 | EAF2 | 55840 | RNAseq | 0.8238 | 0.0053 | |
| SRP133303 | EAF2 | 55840 | RNAseq | 0.4469 | 0.2054 | |
| SRP159526 | EAF2 | 55840 | RNAseq | -0.2360 | 0.7154 | |
| SRP193095 | EAF2 | 55840 | RNAseq | -0.1056 | 0.7401 | |
| SRP219564 | EAF2 | 55840 | RNAseq | 1.0824 | 0.0016 | |
| TCGA | EAF2 | 55840 | RNAseq | 0.4801 | 0.0032 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by EAF2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of EAF2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | EAF2 | 55840 | 18 | 0 | 12 | |
| GSE20123 | EAF2 | 55840 | 18 | 0 | 12 | |
| GSE43470 | EAF2 | 55840 | 20 | 0 | 23 | |
| GSE46452 | EAF2 | 55840 | 14 | 5 | 40 | |
| GSE47630 | EAF2 | 55840 | 16 | 5 | 19 | |
| GSE54993 | EAF2 | 55840 | 2 | 6 | 62 | |
| GSE54994 | EAF2 | 55840 | 30 | 4 | 19 | |
| GSE60625 | EAF2 | 55840 | 0 | 6 | 5 | |
| GSE74703 | EAF2 | 55840 | 16 | 0 | 20 | |
| GSE74704 | EAF2 | 55840 | 13 | 0 | 7 | |
| TCGA | EAF2 | 55840 | 54 | 6 | 36 |
Total number of gains: 201; Total number of losses: 32; Total Number of normals: 255.
Somatic mutations of EAF2:
Generating mutation plots.
Highly correlated genes for EAF2:
Showing top 20/854 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| EAF2 | KDM1B | 0.777414 | 3 | 0 | 3 |
| EAF2 | SORD | 0.764443 | 3 | 0 | 3 |
| EAF2 | POU2AF1 | 0.759019 | 3 | 0 | 3 |
| EAF2 | SERPINE1 | 0.729003 | 3 | 0 | 3 |
| EAF2 | PLEK2 | 0.725661 | 3 | 0 | 3 |
| EAF2 | DDX60L | 0.718482 | 3 | 0 | 3 |
| EAF2 | SLC25A5 | 0.716846 | 3 | 0 | 3 |
| EAF2 | TRADD | 0.708734 | 3 | 0 | 3 |
| EAF2 | STARD10 | 0.708628 | 3 | 0 | 3 |
| EAF2 | HSD17B1 | 0.708066 | 4 | 0 | 4 |
| EAF2 | ADAM15 | 0.703664 | 3 | 0 | 3 |
| EAF2 | KCNA3 | 0.700435 | 4 | 0 | 4 |
| EAF2 | NACC1 | 0.699435 | 3 | 0 | 3 |
| EAF2 | PIF1 | 0.6915 | 3 | 0 | 3 |
| EAF2 | ZNHIT2 | 0.68838 | 3 | 0 | 3 |
| EAF2 | FCF1 | 0.687747 | 3 | 0 | 3 |
| EAF2 | RPL22L1 | 0.686378 | 3 | 0 | 3 |
| EAF2 | WDR18 | 0.683268 | 4 | 0 | 4 |
| EAF2 | FKTN | 0.68311 | 3 | 0 | 3 |
| EAF2 | ZBTB9 | 0.679088 | 4 | 0 | 3 |
For details and further investigation, click here
