| Full name: dipeptidyl peptidase 3 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 11q13.2 | ||
| Entrez ID: 10072 | HGNC ID: HGNC:3008 | Ensembl Gene: ENSG00000254986 | OMIM ID: 606818 |
| Drug and gene relationship at DGIdb | |||
Expression of DPP3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DPP3 | 10072 | 232510_s_at | 0.6700 | 0.2028 | |
| GSE20347 | DPP3 | 10072 | 218567_x_at | 0.5234 | 0.0065 | |
| GSE23400 | DPP3 | 10072 | 218567_x_at | 0.5692 | 0.0000 | |
| GSE26886 | DPP3 | 10072 | 232510_s_at | 0.1402 | 0.5381 | |
| GSE29001 | DPP3 | 10072 | 218567_x_at | 0.4540 | 0.0532 | |
| GSE38129 | DPP3 | 10072 | 218567_x_at | 0.8736 | 0.0000 | |
| GSE45670 | DPP3 | 10072 | 232510_s_at | 0.7544 | 0.0000 | |
| GSE53622 | DPP3 | 10072 | 90428 | 0.4541 | 0.0000 | |
| GSE53624 | DPP3 | 10072 | 90428 | 0.2109 | 0.0038 | |
| GSE63941 | DPP3 | 10072 | 232510_s_at | 0.6954 | 0.1478 | |
| GSE77861 | DPP3 | 10072 | 232510_s_at | 0.4628 | 0.0174 | |
| GSE97050 | DPP3 | 10072 | A_23_P116091 | 0.4551 | 0.1755 | |
| SRP007169 | DPP3 | 10072 | RNAseq | -0.1315 | 0.6614 | |
| SRP008496 | DPP3 | 10072 | RNAseq | -0.1406 | 0.5097 | |
| SRP064894 | DPP3 | 10072 | RNAseq | 0.6256 | 0.0000 | |
| SRP133303 | DPP3 | 10072 | RNAseq | 1.0650 | 0.0000 | |
| SRP159526 | DPP3 | 10072 | RNAseq | 0.7113 | 0.0023 | |
| SRP193095 | DPP3 | 10072 | RNAseq | 0.3288 | 0.0010 | |
| SRP219564 | DPP3 | 10072 | RNAseq | 0.9370 | 0.0062 | |
| TCGA | DPP3 | 10072 | RNAseq | 0.2374 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by DPP3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DPP3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DPP3 | 10072 | 9 | 4 | 17 | |
| GSE20123 | DPP3 | 10072 | 9 | 4 | 17 | |
| GSE43470 | DPP3 | 10072 | 6 | 1 | 36 | |
| GSE46452 | DPP3 | 10072 | 12 | 3 | 44 | |
| GSE47630 | DPP3 | 10072 | 9 | 4 | 27 | |
| GSE54993 | DPP3 | 10072 | 3 | 0 | 67 | |
| GSE54994 | DPP3 | 10072 | 9 | 5 | 39 | |
| GSE60625 | DPP3 | 10072 | 0 | 3 | 8 | |
| GSE74703 | DPP3 | 10072 | 4 | 0 | 32 | |
| GSE74704 | DPP3 | 10072 | 7 | 2 | 11 | |
| TCGA | DPP3 | 10072 | 27 | 6 | 63 |
Total number of gains: 95; Total number of losses: 32; Total Number of normals: 361.
Somatic mutations of DPP3:
Generating mutation plots.
Highly correlated genes for DPP3:
Showing top 20/1472 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DPP3 | ANKRD16 | 0.754657 | 3 | 0 | 3 |
| DPP3 | BRMS1 | 0.750021 | 11 | 0 | 11 |
| DPP3 | GEN1 | 0.743767 | 4 | 0 | 4 |
| DPP3 | SPNS1 | 0.742239 | 3 | 0 | 3 |
| DPP3 | MED19 | 0.738865 | 4 | 0 | 3 |
| DPP3 | CCDC86 | 0.730267 | 7 | 0 | 7 |
| DPP3 | DNMT1 | 0.728333 | 9 | 0 | 9 |
| DPP3 | ZDHHC16 | 0.724416 | 4 | 0 | 4 |
| DPP3 | CARD11 | 0.71997 | 3 | 0 | 3 |
| DPP3 | UHRF1 | 0.717016 | 5 | 0 | 5 |
| DPP3 | STON2 | 0.715316 | 3 | 0 | 3 |
| DPP3 | YDJC | 0.712369 | 5 | 0 | 5 |
| DPP3 | CENPW | 0.711273 | 5 | 0 | 4 |
| DPP3 | PSMG3 | 0.707426 | 5 | 0 | 5 |
| DPP3 | LSM4 | 0.702295 | 9 | 0 | 8 |
| DPP3 | FIBP | 0.701472 | 11 | 0 | 11 |
| DPP3 | TIMELESS | 0.700534 | 9 | 0 | 8 |
| DPP3 | UBE2C | 0.700215 | 10 | 0 | 9 |
| DPP3 | KPNA2 | 0.699624 | 8 | 0 | 7 |
| DPP3 | DBF4 | 0.697154 | 8 | 0 | 8 |
For details and further investigation, click here
