| Full name: WD repeat domain 25 | Alias Symbol: MGC4645 | ||
| Type: protein-coding gene | Cytoband: 14q32.32 | ||
| Entrez ID: 79446 | HGNC ID: HGNC:21064 | Ensembl Gene: ENSG00000176473 | OMIM ID: 618059 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of WDR25:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | WDR25 | 79446 | 219609_at | 0.1934 | 0.6002 | |
| GSE20347 | WDR25 | 79446 | 219609_at | 0.1147 | 0.1949 | |
| GSE23400 | WDR25 | 79446 | 219609_at | 0.0592 | 0.1031 | |
| GSE26886 | WDR25 | 79446 | 219609_at | 0.4561 | 0.0036 | |
| GSE29001 | WDR25 | 79446 | 219609_at | 0.1454 | 0.2430 | |
| GSE38129 | WDR25 | 79446 | 219609_at | 0.0794 | 0.4902 | |
| GSE45670 | WDR25 | 79446 | 219609_at | 0.0704 | 0.5970 | |
| GSE53622 | WDR25 | 79446 | 28651 | 0.3439 | 0.0001 | |
| GSE53624 | WDR25 | 79446 | 28651 | 0.4170 | 0.0000 | |
| GSE63941 | WDR25 | 79446 | 219609_at | 0.0177 | 0.9752 | |
| GSE77861 | WDR25 | 79446 | 219609_at | 0.0113 | 0.9649 | |
| GSE97050 | WDR25 | 79446 | A_23_P84202 | 0.3858 | 0.2087 | |
| SRP007169 | WDR25 | 79446 | RNAseq | -0.2031 | 0.6742 | |
| SRP008496 | WDR25 | 79446 | RNAseq | 0.0320 | 0.9312 | |
| SRP064894 | WDR25 | 79446 | RNAseq | 0.8395 | 0.0083 | |
| SRP133303 | WDR25 | 79446 | RNAseq | 0.4401 | 0.0045 | |
| SRP159526 | WDR25 | 79446 | RNAseq | 0.3194 | 0.4845 | |
| SRP193095 | WDR25 | 79446 | RNAseq | 0.3491 | 0.0306 | |
| SRP219564 | WDR25 | 79446 | RNAseq | 0.7341 | 0.1349 | |
| TCGA | WDR25 | 79446 | RNAseq | -0.1074 | 0.1433 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by WDR25 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of WDR25:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | WDR25 | 79446 | 9 | 5 | 16 | |
| GSE20123 | WDR25 | 79446 | 9 | 4 | 17 | |
| GSE43470 | WDR25 | 79446 | 7 | 4 | 32 | |
| GSE46452 | WDR25 | 79446 | 17 | 3 | 39 | |
| GSE47630 | WDR25 | 79446 | 11 | 8 | 21 | |
| GSE54993 | WDR25 | 79446 | 3 | 8 | 59 | |
| GSE54994 | WDR25 | 79446 | 21 | 4 | 28 | |
| GSE60625 | WDR25 | 79446 | 0 | 2 | 9 | |
| GSE74703 | WDR25 | 79446 | 6 | 3 | 27 | |
| GSE74704 | WDR25 | 79446 | 5 | 3 | 12 | |
| TCGA | WDR25 | 79446 | 31 | 18 | 47 |
Total number of gains: 119; Total number of losses: 62; Total Number of normals: 307.
Somatic mutations of WDR25:
Generating mutation plots.
Highly correlated genes for WDR25:
Showing top 20/585 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| WDR25 | ZNF766 | 0.873487 | 3 | 0 | 3 |
| WDR25 | B9D2 | 0.801394 | 3 | 0 | 3 |
| WDR25 | AKT1S1 | 0.792524 | 3 | 0 | 3 |
| WDR25 | NLK | 0.789633 | 3 | 0 | 3 |
| WDR25 | GAS6-AS1 | 0.783669 | 3 | 0 | 3 |
| WDR25 | UBA52 | 0.782194 | 4 | 0 | 4 |
| WDR25 | CHCHD6 | 0.774455 | 3 | 0 | 3 |
| WDR25 | OSBPL7 | 0.770233 | 3 | 0 | 3 |
| WDR25 | CCDC150 | 0.766881 | 3 | 0 | 3 |
| WDR25 | SMG9 | 0.765646 | 4 | 0 | 3 |
| WDR25 | CCNT1 | 0.763343 | 3 | 0 | 3 |
| WDR25 | RAVER1 | 0.751376 | 3 | 0 | 3 |
| WDR25 | DROSHA | 0.746066 | 3 | 0 | 3 |
| WDR25 | RPS19 | 0.744405 | 3 | 0 | 3 |
| WDR25 | KHSRP | 0.738734 | 4 | 0 | 4 |
| WDR25 | TBCD | 0.737034 | 3 | 0 | 3 |
| WDR25 | ACAD9 | 0.735916 | 3 | 0 | 3 |
| WDR25 | ZNF579 | 0.734454 | 4 | 0 | 4 |
| WDR25 | SCAMP3 | 0.733795 | 3 | 0 | 3 |
| WDR25 | ZNF584 | 0.732123 | 3 | 0 | 3 |
For details and further investigation, click here
