| Full name: oxysterol binding protein like 7 | Alias Symbol: ORP7|MGC71150 | ||
| Type: protein-coding gene | Cytoband: 17q21.32 | ||
| Entrez ID: 114881 | HGNC ID: HGNC:16387 | Ensembl Gene: ENSG00000006025 | OMIM ID: 606735 |
| Drug and gene relationship at DGIdb | |||
Expression of OSBPL7:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | OSBPL7 | 114881 | 227946_at | 0.4661 | 0.5440 | |
| GSE20347 | OSBPL7 | 114881 | 208163_s_at | -0.0047 | 0.9585 | |
| GSE23400 | OSBPL7 | 114881 | 208163_s_at | -0.1351 | 0.0007 | |
| GSE26886 | OSBPL7 | 114881 | 227946_at | 0.3823 | 0.0149 | |
| GSE29001 | OSBPL7 | 114881 | 208163_s_at | -0.1571 | 0.2073 | |
| GSE38129 | OSBPL7 | 114881 | 208163_s_at | -0.0180 | 0.8412 | |
| GSE45670 | OSBPL7 | 114881 | 227946_at | 0.0362 | 0.8539 | |
| GSE63941 | OSBPL7 | 114881 | 227946_at | -0.1155 | 0.8352 | |
| GSE77861 | OSBPL7 | 114881 | 208163_s_at | -0.1112 | 0.2486 | |
| GSE97050 | OSBPL7 | 114881 | A_33_P3358740 | 0.1780 | 0.4239 | |
| SRP064894 | OSBPL7 | 114881 | RNAseq | 0.8528 | 0.0009 | |
| SRP133303 | OSBPL7 | 114881 | RNAseq | -0.0732 | 0.6202 | |
| SRP159526 | OSBPL7 | 114881 | RNAseq | 0.5679 | 0.2527 | |
| SRP193095 | OSBPL7 | 114881 | RNAseq | -0.3556 | 0.3822 | |
| SRP219564 | OSBPL7 | 114881 | RNAseq | 1.6361 | 0.0036 | |
| TCGA | OSBPL7 | 114881 | RNAseq | -0.7914 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by OSBPL7 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of OSBPL7:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | OSBPL7 | 114881 | 5 | 2 | 23 | |
| GSE20123 | OSBPL7 | 114881 | 5 | 2 | 23 | |
| GSE43470 | OSBPL7 | 114881 | 1 | 2 | 40 | |
| GSE46452 | OSBPL7 | 114881 | 32 | 0 | 27 | |
| GSE47630 | OSBPL7 | 114881 | 9 | 0 | 31 | |
| GSE54993 | OSBPL7 | 114881 | 2 | 4 | 64 | |
| GSE54994 | OSBPL7 | 114881 | 11 | 5 | 37 | |
| GSE60625 | OSBPL7 | 114881 | 4 | 0 | 7 | |
| GSE74703 | OSBPL7 | 114881 | 1 | 1 | 34 | |
| GSE74704 | OSBPL7 | 114881 | 4 | 1 | 15 | |
| TCGA | OSBPL7 | 114881 | 28 | 6 | 62 |
Total number of gains: 102; Total number of losses: 23; Total Number of normals: 363.
Somatic mutations of OSBPL7:
Generating mutation plots.
Highly correlated genes for OSBPL7:
Showing top 20/531 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| OSBPL7 | WDR25 | 0.770233 | 3 | 0 | 3 |
| OSBPL7 | KIAA2013 | 0.743692 | 3 | 0 | 3 |
| OSBPL7 | BAG6 | 0.730033 | 3 | 0 | 3 |
| OSBPL7 | RAVER1 | 0.727982 | 3 | 0 | 3 |
| OSBPL7 | BCAN | 0.720833 | 5 | 0 | 5 |
| OSBPL7 | PARP9 | 0.720126 | 3 | 0 | 3 |
| OSBPL7 | ITGB3 | 0.719968 | 4 | 0 | 4 |
| OSBPL7 | CNKSR1 | 0.713111 | 3 | 0 | 3 |
| OSBPL7 | RFNG | 0.703403 | 3 | 0 | 3 |
| OSBPL7 | TFDP3 | 0.685428 | 3 | 0 | 3 |
| OSBPL7 | CCDC87 | 0.683134 | 4 | 0 | 4 |
| OSBPL7 | DCP1B | 0.681925 | 4 | 0 | 3 |
| OSBPL7 | ATG4C | 0.681381 | 3 | 0 | 3 |
| OSBPL7 | LGI2 | 0.678723 | 3 | 0 | 3 |
| OSBPL7 | AURKAIP1 | 0.678194 | 3 | 0 | 3 |
| OSBPL7 | CFHR3 | 0.67717 | 3 | 0 | 3 |
| OSBPL7 | TNFSF8 | 0.676274 | 5 | 0 | 4 |
| OSBPL7 | RAD18 | 0.674449 | 3 | 0 | 3 |
| OSBPL7 | ECE1 | 0.674359 | 3 | 0 | 3 |
| OSBPL7 | F11 | 0.670759 | 4 | 0 | 3 |
For details and further investigation, click here
