| Full name: tubulin folding cofactor D | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 17q25.3 | ||
| Entrez ID: 6904 | HGNC ID: HGNC:11581 | Ensembl Gene: ENSG00000141556 | OMIM ID: 604649 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of TBCD:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TBCD | 6904 | 211052_s_at | 0.4551 | 0.3225 | |
| GSE20347 | TBCD | 6904 | 211052_s_at | -0.0951 | 0.5294 | |
| GSE23400 | TBCD | 6904 | 211052_s_at | 0.0801 | 0.3152 | |
| GSE26886 | TBCD | 6904 | 211052_s_at | 0.1184 | 0.4801 | |
| GSE29001 | TBCD | 6904 | 211052_s_at | -0.0603 | 0.8713 | |
| GSE38129 | TBCD | 6904 | 211052_s_at | -0.0233 | 0.8411 | |
| GSE45670 | TBCD | 6904 | 211052_s_at | -0.0452 | 0.8150 | |
| GSE53622 | TBCD | 6904 | 61762 | -0.1154 | 0.0171 | |
| GSE53624 | TBCD | 6904 | 61762 | 0.0079 | 0.8957 | |
| GSE63941 | TBCD | 6904 | 211052_s_at | -0.7180 | 0.1885 | |
| GSE77861 | TBCD | 6904 | 211052_s_at | 0.0692 | 0.8295 | |
| GSE97050 | TBCD | 6904 | A_24_P275873 | 0.1897 | 0.3275 | |
| SRP007169 | TBCD | 6904 | RNAseq | -0.5735 | 0.1563 | |
| SRP008496 | TBCD | 6904 | RNAseq | -0.7798 | 0.0042 | |
| SRP064894 | TBCD | 6904 | RNAseq | 0.3940 | 0.0315 | |
| SRP133303 | TBCD | 6904 | RNAseq | -0.0078 | 0.9441 | |
| SRP159526 | TBCD | 6904 | RNAseq | 0.2555 | 0.3946 | |
| SRP193095 | TBCD | 6904 | RNAseq | -0.1189 | 0.3959 | |
| SRP219564 | TBCD | 6904 | RNAseq | 0.0177 | 0.9601 | |
| TCGA | TBCD | 6904 | RNAseq | -0.0848 | 0.0817 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TBCD expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TBCD:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TBCD | 6904 | 4 | 5 | 21 | |
| GSE20123 | TBCD | 6904 | 4 | 5 | 21 | |
| GSE43470 | TBCD | 6904 | 3 | 5 | 35 | |
| GSE46452 | TBCD | 6904 | 34 | 0 | 25 | |
| GSE47630 | TBCD | 6904 | 9 | 2 | 29 | |
| GSE54993 | TBCD | 6904 | 2 | 5 | 63 | |
| GSE54994 | TBCD | 6904 | 10 | 6 | 37 | |
| GSE60625 | TBCD | 6904 | 6 | 0 | 5 | |
| GSE74703 | TBCD | 6904 | 3 | 3 | 30 | |
| GSE74704 | TBCD | 6904 | 4 | 4 | 12 | |
| TCGA | TBCD | 6904 | 23 | 16 | 57 |
Total number of gains: 102; Total number of losses: 51; Total Number of normals: 335.
Somatic mutations of TBCD:
Generating mutation plots.
Highly correlated genes for TBCD:
Showing top 20/201 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TBCD | NSD1 | 0.818847 | 3 | 0 | 3 |
| TBCD | SLC39A7 | 0.779881 | 3 | 0 | 3 |
| TBCD | HNRNPUL1 | 0.7779 | 3 | 0 | 3 |
| TBCD | MFSD3 | 0.77616 | 3 | 0 | 3 |
| TBCD | FLYWCH2 | 0.76914 | 3 | 0 | 3 |
| TBCD | STX5 | 0.743125 | 4 | 0 | 3 |
| TBCD | PREB | 0.741497 | 3 | 0 | 3 |
| TBCD | WDR25 | 0.737034 | 3 | 0 | 3 |
| TBCD | UBXN1 | 0.734643 | 3 | 0 | 3 |
| TBCD | NACC1 | 0.733894 | 4 | 0 | 3 |
| TBCD | DCTN1 | 0.72953 | 4 | 0 | 4 |
| TBCD | SRRT | 0.726653 | 3 | 0 | 3 |
| TBCD | INPP5B | 0.723102 | 3 | 0 | 3 |
| TBCD | NLK | 0.721584 | 4 | 0 | 3 |
| TBCD | GPR160 | 0.721195 | 3 | 0 | 3 |
| TBCD | CCDC124 | 0.718967 | 3 | 0 | 3 |
| TBCD | SLC25A39 | 0.715307 | 3 | 0 | 3 |
| TBCD | ANKRD17 | 0.710944 | 3 | 0 | 3 |
| TBCD | POU3F4 | 0.707749 | 3 | 0 | 3 |
| TBCD | GYS1 | 0.703216 | 3 | 0 | 3 |
For details and further investigation, click here
