| Full name: CD247 molecule | Alias Symbol: CD3H|CD3Q | ||
| Type: protein-coding gene | Cytoband: 1q24.2 | ||
| Entrez ID: 919 | HGNC ID: HGNC:1677 | Ensembl Gene: ENSG00000198821 | OMIM ID: 186780 |
| Drug and gene relationship at DGIdb | |||
CD247 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04650 | Natural killer cell mediated cytotoxicity | |
| hsa04660 | T cell receptor signaling pathway | |
| hsa05142 | Chagas disease (American trypanosomiasis) |
Expression of CD247:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CD247 | 919 | 210031_at | 0.1048 | 0.9381 | |
| GSE20347 | CD247 | 919 | 210031_at | -0.1798 | 0.2488 | |
| GSE23400 | CD247 | 919 | 210031_at | -0.1141 | 0.0362 | |
| GSE26886 | CD247 | 919 | 210031_at | -0.0244 | 0.9323 | |
| GSE29001 | CD247 | 919 | 210031_at | -0.0102 | 0.9532 | |
| GSE38129 | CD247 | 919 | 210031_at | -0.2383 | 0.1257 | |
| GSE45670 | CD247 | 919 | 210031_at | 0.0497 | 0.8530 | |
| GSE53622 | CD247 | 919 | 70234 | -0.2027 | 0.3265 | |
| GSE53624 | CD247 | 919 | 70234 | -0.4070 | 0.0146 | |
| GSE63941 | CD247 | 919 | 210031_at | -0.1112 | 0.4409 | |
| GSE77861 | CD247 | 919 | 210031_at | -0.1151 | 0.1805 | |
| GSE97050 | CD247 | 919 | A_33_P3286873 | -0.2564 | 0.2454 | |
| SRP064894 | CD247 | 919 | RNAseq | -0.0605 | 0.8353 | |
| SRP133303 | CD247 | 919 | RNAseq | -0.1746 | 0.6018 | |
| SRP159526 | CD247 | 919 | RNAseq | -0.6304 | 0.5011 | |
| SRP193095 | CD247 | 919 | RNAseq | -0.3243 | 0.1573 | |
| SRP219564 | CD247 | 919 | RNAseq | 0.6736 | 0.2021 | |
| TCGA | CD247 | 919 | RNAseq | 0.2009 | 0.4684 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CD247 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CD247:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CD247 | 919 | 11 | 1 | 18 | |
| GSE20123 | CD247 | 919 | 11 | 1 | 18 | |
| GSE43470 | CD247 | 919 | 7 | 2 | 34 | |
| GSE46452 | CD247 | 919 | 3 | 1 | 55 | |
| GSE47630 | CD247 | 919 | 14 | 0 | 26 | |
| GSE54993 | CD247 | 919 | 0 | 5 | 65 | |
| GSE54994 | CD247 | 919 | 16 | 0 | 37 | |
| GSE60625 | CD247 | 919 | 0 | 0 | 11 | |
| GSE74703 | CD247 | 919 | 7 | 2 | 27 | |
| GSE74704 | CD247 | 919 | 5 | 0 | 15 | |
| TCGA | CD247 | 919 | 44 | 3 | 49 |
Total number of gains: 118; Total number of losses: 15; Total Number of normals: 355.
Somatic mutations of CD247:
Generating mutation plots.
Highly correlated genes for CD247:
Showing top 20/224 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CD247 | OSM | 0.757917 | 3 | 0 | 3 |
| CD247 | BTBD8 | 0.75732 | 3 | 0 | 3 |
| CD247 | ABCC6 | 0.742776 | 3 | 0 | 3 |
| CD247 | TMIGD2 | 0.742172 | 3 | 0 | 3 |
| CD247 | BTBD19 | 0.739652 | 3 | 0 | 3 |
| CD247 | NLRC3 | 0.738572 | 8 | 0 | 7 |
| CD247 | SIGLEC7 | 0.734253 | 4 | 0 | 3 |
| CD247 | WDR83 | 0.728763 | 3 | 0 | 3 |
| CD247 | CEND1 | 0.711972 | 3 | 0 | 3 |
| CD247 | ITGAL | 0.700851 | 10 | 0 | 10 |
| CD247 | WAS | 0.699669 | 9 | 0 | 9 |
| CD247 | CD48 | 0.697822 | 12 | 0 | 10 |
| CD247 | FAM110B | 0.695966 | 3 | 0 | 3 |
| CD247 | JAKMIP2 | 0.694779 | 3 | 0 | 3 |
| CD247 | TRAT1 | 0.687613 | 8 | 0 | 7 |
| CD247 | DTHD1 | 0.685033 | 4 | 0 | 4 |
| CD247 | HAAO | 0.682662 | 4 | 0 | 4 |
| CD247 | MPP2 | 0.680284 | 3 | 0 | 3 |
| CD247 | CD1D | 0.678619 | 5 | 0 | 5 |
| CD247 | GIMAP2 | 0.67829 | 6 | 0 | 6 |
For details and further investigation, click here
