| Full name: COP9 signalosome subunit 7B | Alias Symbol: CSN7B | ||
| Type: protein-coding gene | Cytoband: 2q37.1 | ||
| Entrez ID: 64708 | HGNC ID: HGNC:16760 | Ensembl Gene: ENSG00000144524 | OMIM ID: 616010 |
| Drug and gene relationship at DGIdb | |||
Expression of COPS7B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | COPS7B | 64708 | 219997_s_at | 0.2841 | 0.4665 | |
| GSE20347 | COPS7B | 64708 | 219997_s_at | 0.1162 | 0.3036 | |
| GSE23400 | COPS7B | 64708 | 219997_s_at | 0.0989 | 0.0082 | |
| GSE26886 | COPS7B | 64708 | 225696_at | -0.2390 | 0.4261 | |
| GSE29001 | COPS7B | 64708 | 219997_s_at | 0.1093 | 0.6276 | |
| GSE38129 | COPS7B | 64708 | 219997_s_at | 0.0912 | 0.4481 | |
| GSE45670 | COPS7B | 64708 | 219997_s_at | 0.0532 | 0.6555 | |
| GSE53622 | COPS7B | 64708 | 38442 | 0.3145 | 0.0000 | |
| GSE53624 | COPS7B | 64708 | 38442 | 0.2808 | 0.0000 | |
| GSE63941 | COPS7B | 64708 | 219997_s_at | 0.1720 | 0.5989 | |
| GSE77861 | COPS7B | 64708 | 219997_s_at | 0.0576 | 0.6151 | |
| GSE97050 | COPS7B | 64708 | A_33_P3292297 | 0.1863 | 0.4725 | |
| SRP007169 | COPS7B | 64708 | RNAseq | 0.2682 | 0.5325 | |
| SRP008496 | COPS7B | 64708 | RNAseq | 0.3450 | 0.1806 | |
| SRP064894 | COPS7B | 64708 | RNAseq | 0.3248 | 0.0207 | |
| SRP133303 | COPS7B | 64708 | RNAseq | 0.1995 | 0.0383 | |
| SRP159526 | COPS7B | 64708 | RNAseq | 0.3294 | 0.2281 | |
| SRP193095 | COPS7B | 64708 | RNAseq | 0.3230 | 0.0072 | |
| SRP219564 | COPS7B | 64708 | RNAseq | 0.2656 | 0.3770 | |
| TCGA | COPS7B | 64708 | RNAseq | 0.0407 | 0.4601 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by COPS7B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of COPS7B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | COPS7B | 64708 | 1 | 12 | 17 | |
| GSE20123 | COPS7B | 64708 | 1 | 12 | 17 | |
| GSE43470 | COPS7B | 64708 | 1 | 8 | 34 | |
| GSE46452 | COPS7B | 64708 | 0 | 5 | 54 | |
| GSE47630 | COPS7B | 64708 | 4 | 5 | 31 | |
| GSE54993 | COPS7B | 64708 | 2 | 2 | 66 | |
| GSE54994 | COPS7B | 64708 | 6 | 10 | 37 | |
| GSE60625 | COPS7B | 64708 | 0 | 3 | 8 | |
| GSE74703 | COPS7B | 64708 | 1 | 6 | 29 | |
| GSE74704 | COPS7B | 64708 | 1 | 5 | 14 | |
| TCGA | COPS7B | 64708 | 12 | 27 | 57 |
Total number of gains: 29; Total number of losses: 95; Total Number of normals: 364.
Somatic mutations of COPS7B:
Generating mutation plots.
Highly correlated genes for COPS7B:
Showing top 20/230 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| COPS7B | WDR83 | 0.787498 | 3 | 0 | 3 |
| COPS7B | SLC18A3 | 0.768542 | 3 | 0 | 3 |
| COPS7B | GPR150 | 0.76286 | 3 | 0 | 3 |
| COPS7B | C2CD4D | 0.750956 | 3 | 0 | 3 |
| COPS7B | TAS2R30 | 0.745063 | 3 | 0 | 3 |
| COPS7B | MIIP | 0.743262 | 5 | 0 | 4 |
| COPS7B | TNNI2 | 0.739779 | 3 | 0 | 3 |
| COPS7B | ZNF646 | 0.728059 | 3 | 0 | 3 |
| COPS7B | PDE6C | 0.727801 | 3 | 0 | 3 |
| COPS7B | NPM2 | 0.718916 | 3 | 0 | 3 |
| COPS7B | IER5L | 0.717564 | 3 | 0 | 3 |
| COPS7B | ITGA2B | 0.714076 | 5 | 0 | 4 |
| COPS7B | NTNG2 | 0.708646 | 4 | 0 | 3 |
| COPS7B | PYGO2 | 0.708309 | 3 | 0 | 3 |
| COPS7B | ZNF446 | 0.708217 | 4 | 0 | 4 |
| COPS7B | FZD9 | 0.707907 | 3 | 0 | 3 |
| COPS7B | RAB40B | 0.707442 | 3 | 0 | 3 |
| COPS7B | KLHL14 | 0.701566 | 4 | 0 | 3 |
| COPS7B | ODF3L2 | 0.697288 | 3 | 0 | 3 |
| COPS7B | TAS2R31 | 0.697283 | 3 | 0 | 3 |
For details and further investigation, click here
